PDB: 98 件ウェブページステータス検索Chemie searchBIRD

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6MDF	Mevalonate kinase from Methanosarcina mazei with 5-phosphomevalonate bound 分子名称: (3R)-3-HYDROXY-3-METHYL-5-(PHOSPHONOOXY)PENTANOIC ACID, GLYCEROL, Mevalonate kinase 著者 Miller, B.R, Kung, Y. 登録日 2018-09-04 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Structural insight into substrate and product binding in an archaeal mevalonate kinase. PLoS ONE, 13, 2018
5WAT	Corynebacterium glutamicum Full length Homoserine kinase 分子名称: HEXAETHYLENE GLYCOL, Homoserine kinase, MAGNESIUM ION, ... 著者 Petit, C, Ronning, D.R. 登録日 2017-06-27 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.141 Å) 主引用文献 Reduction of Feedback Inhibition in Homoserine Kinase (ThrB) ofCorynebacterium glutamicumEnhances l-Threonine Biosynthesis. ACS Omega, 3, 2018
1VIS	Crystal structure of mevalonate kinase 分子名称: 1,4-DIETHYLENE DIOXIDE, Mevalonate kinase 著者 Structural GenomiX 登録日 2003-12-01 公開日 2003-12-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
4EMD	Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to CMP and SO4 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CYTIDINE-5'-MONOPHOSPHATE, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-04-11 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2A2C	x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate 分子名称: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
2OI2	Streptococcus pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, MAGNESIUM ION, Mevalonate kinase 著者 Andreassi, J.L, Bilder, P.W, Vetting, M.W, Roderick, S.L, Leyh, T.S. 登録日 2007-01-10 公開日 2007-05-01 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate. Protein Sci., 16, 2007
2CZ9	Crystal Structure of galactokinase from Pyrococcus horikoshi 分子名称: CHLORIDE ION, GLYCEROL, Probable galactokinase 著者 Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-12 公開日 2006-09-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of galactokinase from Pyrococcus horikoshi To be Published
6N10	Crystal structure of Arabidopsis thaliana mevalonate 5-diphosphate decarboxylase 1 complexed with (R)-MVAPP 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase MVD1, peroxisomal, ... 著者 Noel, J.P, Thomas, S.T, Louie, G.V. 登録日 2018-11-07 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
2A2D	X-ray structure of human n-acetyl galactosamine kinase complexed with Mn-AMPPNP and n-acetyl glactosamine 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, MANGANESE (II) ION, N-acetylgalactosamine kinase, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-05 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
3HUL	Structure of putative homoserine kinase thrB from Listeria monocytogenes 分子名称: Homoserine kinase, SULFATE ION 著者 Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-06-15 公開日 2009-07-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structure of putative homoserine kinase thrB from Listeria monocytogenes To be published
5WAS	Corynebacterium glutamicum Hydrolyzed Homoserine kinase 分子名称: Homoserine kinase, PHOSPHATE ION 著者 Petit, C, Ronning, D.R. 登録日 2017-06-27 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Reduction of Feedback Inhibition in Homoserine Kinase (ThrB) ofCorynebacterium glutamicumEnhances l-Threonine Biosynthesis. ACS Omega, 3, 2018
5YYS	Cryo-EM structure of L-fucokinase, GDP-fucose pyrophosphorylase (FKP)in Bacteroides fragilis 分子名称: L-fucokinase, L-fucose-1-P guanylyltransferase 著者 Wang, J, Hu, H, Liu, Y, Zhou, Q, Wu, P, Yan, N, Wang, H.W, Wu, J.W, Sun, L. 登録日 2017-12-11 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM structure of L-fucokinase/GDP-fucose pyrophosphorylase (FKP) in Bacteroides fragilis. Protein Cell, 10, 2019
2AJ4	Crystal structure of Saccharomyces cerevisiae Galactokinase in complex with galactose and Mg:AMPPNP 分子名称: CHLORIDE ION, Galactokinase, MAGNESIUM ION, ... 著者 Thoden, J.B, Sellick, C.A, Timson, D.J, Reece, R.J, Holden, H.M. 登録日 2005-08-01 公開日 2005-08-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer J.Biol.Chem., 280, 2005
1WUU	crystal structure of human galactokinase complexed with MgAMPPNP and galactose 分子名称: Galactokinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Thoden, J.B, Timson, D.J, Reece, R.J, Holden, H.M. 登録日 2004-12-08 公開日 2004-12-28 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular Structure of Human Galactokinase: IMPLICATIONS FOR TYPE II GALACTOSEMIA J.Biol.Chem., 280, 2005
4ED4	Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to ATP 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-03-26 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2R42	The Biochemical and Structural Basis for feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism 分子名称: MAGNESIUM ION, Mevalonate kinase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE 著者 Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P. 登録日 2007-08-30 公開日 2008-06-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism. Biochemistry, 47, 2008
2R3V	The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism 分子名称: Mevalonate kinase 著者 Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P. 登録日 2007-08-30 公開日 2008-06-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism. Biochemistry, 47, 2008
7RCL	Crystal Structure of ADP-bound Galactokinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ... 著者 Whitby, F.G, Hall, M.D. 登録日 2021-07-07 公開日 2021-09-29 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
7RCM	Crystal Structure of ADP-bound Galactokinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Galactokinase, ... 著者 Whitby, F.G. 登録日 2021-07-07 公開日 2021-09-29 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
7S49	Crystal Structure of Inhibitor-bound Galactokinase 分子名称: (4R)-2-[(1,3-benzoxazol-2-yl)amino]-4-(4-chloro-1H-pyrazol-5-yl)-4,6,7,8-tetrahydroquinazolin-5(1H)-one, Galactokinase, PHOSPHATE ION, ... 著者 Whitby, F.G. 登録日 2021-09-08 公開日 2021-09-29 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
7S4C	Crystal Structure of Inhibitor-bound Galactokinase 分子名称: 2-({(4R)-4-(2-chlorophenyl)-2-[(6-fluoro-1,3-benzoxazol-2-yl)amino]-6-methyl-1,4-dihydropyrimidine-5-carbonyl}amino)pyridine-4-carboxylic acid, Galactokinase, PHOSPHATE ION, ... 著者 Whitby, F.G. 登録日 2021-09-08 公開日 2021-09-29 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
8QC7	New monoclinic EcIspE 分子名称: 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hamid, R. 登録日 2023-08-25 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 New monoclinic EcIspE To Be Published
8QCC	E.coli IspE in complex with a ligand (1) 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Hamid, R. 登録日 2023-08-25 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 E.coli IspE in complex with a ligand (1) To Be Published
8QCN	E.coli IspE in complex with a ligand (2) 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE, ~{N}-[3-(4-azanyl-2-oxidanylidene-1~{H}-pyrimidin-5-yl)prop-2-ynyl]cyclopropanesulfonamide 著者 Hamid, R. 登録日 2023-08-27 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 E.coli IspE in complex with a ligand (2) To Be Published
8QCO	E.coli IspE in complex with a ligand (3) 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE, ~{N}-[3-(4-azanyl-2-oxidanylidene-1~{H}-pyrimidin-5-yl)prop-2-ynyl]cyclopentanesulfonamide 著者 Hamid, R. 登録日 2023-08-28 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 E.coli IspE in complex with a ligand (3) To Be Published

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