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6TZ3
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Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+
分子名称: SULFATE ION, Synaptotagmin-1
著者Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B.
登録日2019-08-09
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
6U41
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BU of 6u41 by Molmil
1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G)
分子名称: SULFATE ION, Synaptotagmin-1
著者Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B.
登録日2019-08-22
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
3N5A
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Synaptotagmin-7, C2B-domain, calcium bound
分子名称: CALCIUM ION, Synaptotagmin-7
著者Tomchick, D.R, Rizo, J, Craig, T.K.
登録日2010-05-24
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.441 Å)
主引用文献Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.
Plos One, 5, 2010
3PYC
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BU of 3pyc by Molmil
Crystal structure of human SMURF1 C2 domain
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase SMURF1, SULFATE ION
著者Li, X, Li, P.
登録日2010-12-13
公開日2011-04-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of human SMURF1 C2 domain
To be Published
5A52
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BU of 5a52 by Molmil
The crystal structure of Arabidopsis thaliana CAR1 in complex with one calcium ion
分子名称: CALCIUM ION, CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN, GLYCEROL, ...
著者Fernandez, D, Marquez, J.A.
登録日2015-06-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling.
Proc.Natl.Acad.Sci.USA, 113, 2016
5VFE
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Synaptotagmin 1 C2A domain, lead-bound
分子名称: LEAD (II) ION, SULFATE ION, Synaptotagmin-1
著者Taylor, A.B, Hart, P.J, Igumenova, T.I.
登録日2017-04-07
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献High affinity interactions of Pb2+with synaptotagmin I.
Metallomics, 10, 2018
5A4X
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The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions and Zn
分子名称: AT3G17980, CALCIUM ION, ZINC ION
著者Diaz, M, Albert, A.
登録日2015-06-15
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling.
Proc.Natl.Acad.Sci.USA, 113, 2016
5A50
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The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions, Zn and Phopho Choline
分子名称: AT3G17980, CALCIUM ION, PHOSPHOCHOLINE, ...
著者Diaz, M, Albert, A.
登録日2015-06-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling.
Proc.Natl.Acad.Sci.USA, 113, 2016
1RH8
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BU of 1rh8 by Molmil
Three-dimensional structure of the calcium-free Piccolo C2A-domain
分子名称: Piccolo protein
著者Garcia, J, Gerber, S.H, Sugita, S, Sudhof, T.C, Rizo, J.
登録日2003-11-14
公開日2004-01-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A conformational switch in the Piccolo C2A domain regulated by alternative splicing.
Nat.Struct.Mol.Biol., 11, 2004
1RLW
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BU of 1rlw by Molmil
CALCIUM-PHOSPHOLIPID BINDING DOMAIN FROM CYTOSOLIC PHOSPHOLIPASE A2
分子名称: CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE A2
著者Perisic, O, Williams, R.L.
登録日1997-10-28
公開日1998-02-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2.
J.Biol.Chem., 273, 1998
4ICX
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BU of 4icx by Molmil
N-terminal C2 domain of human CEP120
分子名称: Centrosomal protein of 120 kDa
著者Janowski, R, Guarin, N, Coll, M.
登録日2012-12-11
公開日2014-06-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献N-terminal C2 domain tandem of human CEP120 shows lipid binding properties
To be Published
4ICW
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N-terminal C2 domain of human CEP120
分子名称: Centrosomal protein of 120 kDa
著者Janowski, R, Guarin, N, Coll, M.
登録日2012-12-11
公開日2014-06-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献N-terminal C2 domain tandem of human CEP120 shows lipid binding properties
To be Published
1RSY
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BU of 1rsy by Molmil
STRUCTURE OF THE FIRST C2-DOMAIN OF SYNAPTOTAGMIN I: A NOVEL CA2+(SLASH)PHOSPHOLIPID BINDING FOLD
分子名称: SULFATE ION, SYNAPTOTAGMIN I
著者Sutton, R.B, Sprang, S.R.
登録日1995-02-01
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold.
Cell(Cambridge,Mass.), 80, 1995
6ANJ
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BU of 6anj by Molmil
Synaptotagmin-7, C2A domain
分子名称: ACETATE ION, CALCIUM ION, Synaptotagmin-7, ...
著者Tomchick, D.R, Rizo, J, Voleti, R.
登録日2017-08-13
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ANK
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BU of 6ank by Molmil
Synaptotagmin-7, C2A- and C2B-domains
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7
著者Tomchick, D.R, Rizo, J, Voleti, R.
登録日2017-08-13
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.254 Å)
主引用文献Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2NQ3
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BU of 2nq3 by Molmil
Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
分子名称: CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase
著者Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-10-30
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
To be Published
2NCE
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BU of 2nce by Molmil
Solution Structure of Ca2+-bound C2 domain from Protein Kinase C alpha in the form of complex with V5-pHM peptide
分子名称: CALCIUM ION, Protein kinase C alpha type
著者Yang, Y, Igumenova, T.I.
登録日2016-03-28
公開日2017-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ca2+-sensing domain contributes to auto-inhibition of protein kinase Calpha through interactions with C-terminal tail
To be Published
6BTY
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BU of 6bty by Molmil
Crystal structure of the PI3KC2alpha C2 domain in space group P41212
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.678 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
2NSQ
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BU of 2nsq by Molmil
Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL
著者Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-11-06
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
To be Published
6BU0
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BU of 6bu0 by Molmil
Crystal structure of the PI3KC2alpha C2 domain in complex with IP6
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ...
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.427 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6CXW
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Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function
分子名称: Synaptotagmin 1 C2A beta4 chimera
著者Sutton, R.B.
登録日2018-04-04
公開日2019-04-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.832 Å)
主引用文献Engineering a C2-domain to bind PIP2
To Be Published
6BTZ
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BU of 6btz by Molmil
Crystal structure of the PI3KC2alpha C2 domain in space group C121
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ...
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
2Q3X
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The RIM1alpha C2B domain
分子名称: CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ...
著者Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J.
登録日2007-05-30
公開日2007-08-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution.
Biochemistry, 46, 2007
4RJ9
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BU of 4rj9 by Molmil
Structure of a plant specific C2 domain protein, OsGAP1 from rice
分子名称: C2 domain-containing protein-like, POTASSIUM ION
著者Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M.
登録日2014-10-08
公開日2015-08-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1).
J.Biol.Chem., 290, 2015
1A25
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C2 DOMAIN FROM PROTEIN KINASE C (BETA)
分子名称: CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA)
著者Sutton, R.B, Sprang, S.R.
登録日1998-01-16
公開日1998-05-06
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.
Structure, 6, 1998

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