6TZ3
| Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+ | 分子名称: | SULFATE ION, Synaptotagmin-1 | 著者 | Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B. | 登録日 | 2019-08-09 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
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6U41
| 1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G) | 分子名称: | SULFATE ION, Synaptotagmin-1 | 著者 | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | 登録日 | 2019-08-22 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
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3N5A
| Synaptotagmin-7, C2B-domain, calcium bound | 分子名称: | CALCIUM ION, Synaptotagmin-7 | 著者 | Tomchick, D.R, Rizo, J, Craig, T.K. | 登録日 | 2010-05-24 | 公開日 | 2010-09-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.441 Å) | 主引用文献 | Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. Plos One, 5, 2010
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3PYC
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5A52
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5VFE
| Synaptotagmin 1 C2A domain, lead-bound | 分子名称: | LEAD (II) ION, SULFATE ION, Synaptotagmin-1 | 著者 | Taylor, A.B, Hart, P.J, Igumenova, T.I. | 登録日 | 2017-04-07 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | High affinity interactions of Pb2+with synaptotagmin I. Metallomics, 10, 2018
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5A4X
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5A50
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1RH8
| Three-dimensional structure of the calcium-free Piccolo C2A-domain | 分子名称: | Piccolo protein | 著者 | Garcia, J, Gerber, S.H, Sugita, S, Sudhof, T.C, Rizo, J. | 登録日 | 2003-11-14 | 公開日 | 2004-01-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A conformational switch in the Piccolo C2A domain regulated by alternative splicing. Nat.Struct.Mol.Biol., 11, 2004
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1RLW
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4ICX
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4ICW
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1RSY
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6ANJ
| Synaptotagmin-7, C2A domain | 分子名称: | ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | 登録日 | 2017-08-13 | 公開日 | 2017-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6ANK
| Synaptotagmin-7, C2A- and C2B-domains | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7 | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | 登録日 | 2017-08-13 | 公開日 | 2017-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.254 Å) | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2NQ3
| Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase | 分子名称: | CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-10-30 | 公開日 | 2006-11-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase To be Published
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2NCE
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6BTY
| Crystal structure of the PI3KC2alpha C2 domain in space group P41212 | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | 著者 | Chen, K.-E, Collins, B.M. | 登録日 | 2017-12-08 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.678 Å) | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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2NSQ
| Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-06 | 公開日 | 2006-12-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein To be Published
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6BU0
| Crystal structure of the PI3KC2alpha C2 domain in complex with IP6 | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Chen, K.-E, Collins, B.M. | 登録日 | 2017-12-08 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.427 Å) | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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6CXW
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6BTZ
| Crystal structure of the PI3KC2alpha C2 domain in space group C121 | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ... | 著者 | Chen, K.-E, Collins, B.M. | 登録日 | 2017-12-08 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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2Q3X
| The RIM1alpha C2B domain | 分子名称: | CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ... | 著者 | Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J. | 登録日 | 2007-05-30 | 公開日 | 2007-08-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution. Biochemistry, 46, 2007
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4RJ9
| Structure of a plant specific C2 domain protein, OsGAP1 from rice | 分子名称: | C2 domain-containing protein-like, POTASSIUM ION | 著者 | Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M. | 登録日 | 2014-10-08 | 公開日 | 2015-08-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1). J.Biol.Chem., 290, 2015
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1A25
| C2 DOMAIN FROM PROTEIN KINASE C (BETA) | 分子名称: | CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA) | 著者 | Sutton, R.B, Sprang, S.R. | 登録日 | 1998-01-16 | 公開日 | 1998-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+. Structure, 6, 1998
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