PDB: 974 件ウェブページステータス検索Chemie searchBIRD

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2R9X	AmpC beta-lactamase with bound Phthalamide inhibitor 分子名称: 2-[(1R)-2-carboxy-1-(naphthalen-1-ylmethyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid, Beta-lactamase, DIMETHYL SULFOXIDE, ... 著者 Babaoglu, K, Shoichet, B.K. 登録日 2007-09-13 公開日 2008-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase. J.Med.Chem., 51, 2008
2R9W	AmpC beta-lactamase with bound Phthalamide inhibitor 分子名称: 2-[(1R)-1-carboxy-2-naphthalen-1-ylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Babaoglu, K, Shoichet, B.K. 登録日 2007-09-13 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase. J.Med.Chem., 51, 2008
2RCX	AmpC Beta-lactamase in complex with (1R)-1-(2-Thiophen-2-yl-acetylamino)-1-(3-(2-carboxyvinyl)-phenyl) methylboronic acid 分子名称: (1R)-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-1-(3-(2-CARBOXYVINYL)-PHENYL) METHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION 著者 Morandi, F, Morandi, S, Prati, F, Shoichet, B.K. 登録日 2007-09-20 公開日 2007-11-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based optimization of cephalothin-analogue boronic acids as beta-lactamase inhibitors Bioorg.Med.Chem., 16, 2008
5K1D	Crystal structure of a class C beta lactamase/compound1 complex 分子名称: Beta-lactamase, CADMIUM ION, GUANOSINE-5'-MONOPHOSPHATE 著者 AN, Y.J, Na, J.H, Cha, S.S. 登録日 2016-05-18 公開日 2017-05-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 GMP and IMP Are Competitive Inhibitors of CMY-10, an Extended-Spectrum Class C beta-Lactamase. Antimicrob. Agents Chemother., 61, 2017
5JOC	Crystal structure of the S61A mutant of AmpC BER 分子名称: Beta-lactamase, CITRIC ACID 著者 Na, J.H, An, Y.J, Cha, S.S. 登録日 2016-05-02 公開日 2017-05-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for the extended substrate spectrum of AmpC BER and structure-guided discovery of the inhibition activity of citrate against the class C beta-lactamases AmpC BER and CMY-10. Acta Crystallogr D Struct Biol, 72, 2016
5K1F	Crystal structure of a class C beta lactamase/compound2 complex 分子名称: Beta-lactamase, CADMIUM ION, INOSINIC ACID 著者 An, Y.J, Na, J.H, Cha, S.S. 登録日 2016-05-18 公開日 2017-05-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 GMP and IMP Are Competitive Inhibitors of CMY-10, an Extended-Spectrum Class C beta-Lactamase. Antimicrob. Agents Chemother., 61, 2017
7CIN	Crystal structure of the extended-spectrum class C beta-lactamase AmpC BER with the ordered R2 loop 分子名称: Beta-lactamase, SULFATE ION 著者 Jeong, B.G, Cha, S.S. 登録日 2020-07-07 公開日 2021-05-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.79006362 Å) 主引用文献 Crystal structure of AmpC BER and molecular docking lead to the discovery of broad inhibition activities of halisulfates against beta-lactamases. Comput Struct Biotechnol J, 19, 2021
2WZZ	AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA)IN COMPLEX WITH compound M-03 分子名称: (3R)-1-[(4R)-AZEPAN-4-YLCARBAMOYL]-3-(SULFOAMINO)-L-PROLINE, BETA-LACTAMASE, CHLORIDE ION 著者 Fitzgerald, P.M.D, Sharma, N, Lu, J. 登録日 2009-12-03 公開日 2010-01-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Side Chain Sar of Bicyclic Beta-Lactamase Inhibitors (Blis). 1. Discovery of a Class C Bli for Combination with Imipinem. Bioorg.Med.Chem.Lett., 20, 2010
7MQN	Crystal structure of class C beta lactamase from Rhodobacter sphaeroides 分子名称: Beta-lactamase, PHOSPHATE ION 著者 Chang, C, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-05-05 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of class C beta lactamase from Rhodobacter sphaeroides To Be Published
7MDE	Full-length S95A ClbP 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... 著者 Velilla, J.A, Volpe, M.R, Gaudet, R. 登録日 2021-04-04 公開日 2022-09-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of colibactin activation by the ClbP peptidase. Nat.Chem.Biol., 19, 2023
7MDF	Full-length S95A ClbP bound to N-acyl-D-asparagine analog 分子名称: (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... 著者 Velilla, J.A, Volpe, M.R, Gaudet, R. 登録日 2021-04-04 公開日 2022-09-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of colibactin activation by the ClbP peptidase. Nat.Chem.Biol., 19, 2023
7MDC	Full-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acid 分子名称: (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... 著者 Velilla, J.A, Volpe, M.R, Gaudet, R. 登録日 2021-04-03 公開日 2022-09-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A small molecule inhibitor prevents gut bacterial genotoxin production. Nat.Chem.Biol., 19, 2023
2WZX	AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA)IN COMPLEX WITH compound M-02 分子名称: (3R)-1-[(4S)-azepan-4-ylcarbamoyl]-3-(sulfoamino)-L-proline, BETA-LACTAMASE, CHLORIDE ION 著者 Fitzgerald, P.M.D, Sharma, N, Lu, J. 登録日 2009-12-03 公開日 2010-01-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Side Chain Sar of Bicyclic Beta-Lactamase Inhibitors (Blis). 1. Discovery of a Class C Bli for Combination with Imipinem. Bioorg.Med.Chem.Lett., 20, 2010
2WK0	Crystal structure of the class A beta-lactamase BS3 inhibited by 6- beta-iodopenicillanate. 分子名称: (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, BETA-LACTAMASE, CHLORIDE ION, ... 著者 Sauvage, E, Zervosen, A, Dive, G, Herman, R, Kerff, F, Amoroso, A, Fonze, E, Pratt, R.F, Luxen, A, Charlier, P. 登録日 2009-06-03 公開日 2009-12-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate. J.Am.Chem.Soc., 131, 2009
4Y7P	Structure of alkaline D-peptidase from Bacillus cereus 分子名称: Alkaline D-peptidase, THIOCYANATE ION 著者 Nakano, S, Okazaki, S, Ishitsubo, E, Kawahara, N, Komeda, H, Tokiwa, H, Asano, Y. 登録日 2015-02-15 公開日 2015-10-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and computational analysis of peptide recognition mechanism of class-C type penicillin binding protein, alkaline D-peptidase from Bacillus cereus DF4-B Sci Rep, 5, 2015
2BLS	AMPC BETA-LACTAMASE FROM ESCHERICHIA COLI 分子名称: AMPC BETA-LACTAMASE 著者 Usher, K.C, Wery, J.-P, Blaszczak, L.C, Remington, S.J. 登録日 1998-06-03 公開日 1998-08-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Three-dimensional structure of AmpC beta-lactamase from Escherichia coli bound to a transition-state analogue: possible implications for the oxyanion hypothesis and for inhibitor design. Biochemistry, 37, 1998
2DCF	Crystal structure of 6-aminohexanoate-dimer hydrolase S112A/G181D/H266N mutant with substrate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-AMINOHEXANOIC ACID, 6-aminohexanoate-dimer hydrolase, ... 著者 Ohki, T, Shibata, N, Higuchi, Y, Takeo, M, Negoro, S. 登録日 2006-01-06 公開日 2007-01-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Nylon-oligomer degrading enzyme/substrate complex: catalytic mechanism of 6-aminohexanoate-dimer hydrolase J.Mol.Biol., 370, 2007
2E8I	Structure of 6-aminohexanoate-dimer hydrolase, D1 mutant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-aminohexanoate-dimer hydrolase, GLYCEROL, ... 著者 Shibata, N, Higuchi, Y, Negoro, S. 登録日 2007-01-20 公開日 2008-01-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a beta-lactamase fold. Febs J., 276, 2009
2BLM	BETA-LACTAMASE OF BACILLUS LICHENIFORMIS 749(SLASH)C AT 2 ANGSTROMS RESOLUTION 分子名称: BETA-LACTAMASE 著者 Moews, P.C, Knox, J.R, Dideberg, O. 登録日 1990-02-02 公開日 1990-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution. Proteins, 7, 1990
2EFU	The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with L-phenylalanine 分子名称: BARIUM ION, D-Amino acid amidase, PHENYLALANINE 著者 Okazaki, S, Suzuki, A, Mizushima, T, Komeda, H, Asano, Y, Yamane, T. 登録日 2007-02-26 公開日 2007-03-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3. Acta Crystallogr.,Sect.D, 64, 2008
2DRW	The crystal structutre of D-amino acid amidase from Ochrobactrum anthropi SV3 分子名称: BARIUM ION, D-Amino acid amidase 著者 Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. 登録日 2006-06-15 公開日 2006-07-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins J.Mol.Biol., 368, 2007
2DNS	The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with D-Phenylalanine 分子名称: BARIUM ION, D-PHENYLALANINE, D-amino acid amidase 著者 Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. 登録日 2006-04-26 公開日 2006-05-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins J.Mol.Biol., 368, 2007
2EFX	The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with L-phenylalanine amide 分子名称: BARIUM ION, D-amino acid amidase, PHENYLALANINE AMIDE 著者 Okazaki, S, Suzuki, A, Mizushima, T, Komeda, H, Asano, Y, Yamane, T. 登録日 2007-02-26 公開日 2007-03-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3. Acta Crystallogr.,Sect.D, 64, 2008
2FFY	AmpC beta-lactamase N289A mutant in complex with a boronic acid deacylation transition state analog compound SM3 分子名称: (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION, ... 著者 Chen, Y, Minasov, G, Roth, T.A, Prati, F, Shoichet, B.K. 登録日 2005-12-20 公開日 2006-03-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution J.Am.Chem.Soc., 128, 2006
7PP8	STRUCTURE OF ESTER-HYDROLASE EH7 FROM METAGENOME OF MARINE SEDIMENTS AT MILAZZO HARBOR (SICILY, ITALY) COMPLEXED WITH A DERIVATIVE OF METHYL 4-NITROPHENYL HEXYLPHOSPHONATE 分子名称: DI(HYDROXYETHYL)ETHER, Esterase, GLYCEROL, ... 著者 Cea-Rama, I, Sanz-Aparicio, J. 登録日 2021-09-13 公開日 2022-07-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of a family VIII beta-lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope. Febs J., 289, 2022

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