PDB: 271 件ウェブページステータス検索Chemie searchBIRD

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8G9N	Partial DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8HG1	The structure of MPXV polymerase holoenzyme in replicating state 分子名称: DNA (25-MER), DNA (38-MER), DNA polymerase, ... 著者 Peng, Q, Xie, Y.F, Kuai, L, Wang, H, Qi, J.X, Gao, F, Shi, Y. 登録日 2022-11-13 公開日 2022-12-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure of monkeypox virus DNA polymerase holoenzyme. Science, 379, 2023
7TQW	Kod RSGA incorporating PMT, n+2 分子名称: DNA polymerase, Primer, Template 著者 Hajjar, M, Chim, N, Chaput, J.C. 登録日 2022-01-27 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
7RSS	Kod-RI incorporating DNA, n+2 分子名称: DNA polymerase, Primer, Template 著者 Hajjar, M, Chim, N, Chaput, J.C. 登録日 2021-08-11 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
7RSR	Kod-RI incorporating PMT, n+2 分子名称: DNA polymerase, Primer, Template 著者 Hajjar, M, Chim, N, Chaput, J.C. 登録日 2021-08-11 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
7UY7	Tetrahymena CST with Polymerase alpha-Primase 分子名称: DNA polymerase, Telomerase associated protein p50, Telomerase-associated protein of 19 kDa, ... 著者 He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. 登録日 2022-05-06 公開日 2022-07-13 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
7UY8	Tetrahymena Polymerase alpha-Primase 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. 登録日 2022-05-06 公開日 2022-07-13 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
8D0K	Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC 分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... 著者 He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. 登録日 2022-05-26 公開日 2022-06-22 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4.27 Å) 主引用文献 Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Nature, 608, 2022
8D0B	Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template 分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... 著者 He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. 登録日 2022-05-26 公開日 2022-06-22 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Nature, 608, 2022
7U5C	Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state 分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... 著者 Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T. 登録日 2022-03-02 公開日 2022-05-18 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state. Nat.Struct.Mol.Biol., 29, 2022
7N2M	Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*T*AP*GP*TP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), DNA polymerase alpha catalytic subunit, ... 著者 Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. 登録日 2021-05-29 公開日 2022-04-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and functional insight into mismatch extension by human DNA polymerase alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
7S0T	Structure of DNA polymerase zeta with mismatched DNA 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... 著者 Malik, R, Ubarretxena, I.B, Aggarwal, A.K. 登録日 2021-08-31 公開日 2022-03-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Cryo-EM structure of translesion DNA synthesis polymerase zeta with a base pair mismatch. Nat Commun, 13, 2022
7OPL	CryoEM structure of DNA Polymerase alpha - primase bound to SARS CoV nsp1 分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... 著者 Kilkenny, M.L, Pellegrini, L. 登録日 2021-06-01 公開日 2021-11-10 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.12 Å) 主引用文献 Structural basis for the interaction of SARS-CoV-2 virulence factor nsp1 with DNA polymerase alpha-primase. Protein Sci., 31, 2022
7RSU	TNA polymerase, n+2 product 分子名称: DNA polymerase, Primer, Template 著者 Maola, V, Chaput, J, Chim, N. 登録日 2021-08-11 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities. J.Am.Chem.Soc., 143, 2021
7OMB	Crystal structure of KOD DNA Polymerase in a ternary complex with a p/t duplex containing an extended 5' single stranded template overhang 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, ... 著者 Betz, K, Kropp, H.M, Diederichs, K, Marx, A. 登録日 2021-05-21 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem, 22, 2021
7OMG	Crystal structure of KOD DNA Polymerase in a ternary complex with an Uracil containing template 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, ... 著者 Betz, K, Kropp, H.M, Diederichs, K, Marx, A. 登録日 2021-05-22 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem, 22, 2021
7OM3	Crystal structure of KOD DNA Polymerase in a binary complex with Hypoxanthine containing template 分子名称: 1,2-ETHANEDIOL, 21nt Template, BROMIDE ION, ... 著者 Betz, K, Kropp, H.M, Diederichs, K, Marx, A. 登録日 2021-05-21 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem, 22, 2021
7F4Y	Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*AP*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), ... 著者 Youn, H.-S, Park, J, An, J.Y, Lee, Y, Eom, S.H, Wang, J. 登録日 2021-06-21 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of New Binary and Ternary DNA Polymerase Complexes From Bacteriophage RB69. Front Mol Biosci, 8, 2021
7LXD	Structure of yeast DNA Polymerase Zeta (apo) 分子名称: DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... 著者 Truong, C.D, Craig, T.A, Cui, G, Botuyan, M.V, Serkasevich, R.A, Chan, K.-Y, Mer, G, Chiu, P.-L, Kumar, R. 登録日 2021-03-03 公開日 2021-06-30 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.11 Å) 主引用文献 Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta. J.Biol.Chem., 297, 2021
7LUF	HSV1 polymerase ternary complex with dsDNA and PNU-183792 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... 著者 Hayes, R.P, Klein, D. 登録日 2021-02-22 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase. Nat Commun, 12, 2021
7B0H	TgoT_6G12 Ternary complex 分子名称: DNA (5'-D(P*AP*AP*CP*GP*GP*CP*AP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ... 著者 Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. 登録日 2020-11-19 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
7B08	TgoT apo 分子名称: DNA polymerase, THYMIDINE-5'-TRIPHOSPHATE, TRIETHYLENE GLYCOL 著者 Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. 登録日 2020-11-18 公開日 2020-12-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.394 Å) 主引用文献 Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
7B07	TgoT_6G12 apo 分子名称: CALCIUM ION, DNA polymerase 著者 Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. 登録日 2020-11-18 公開日 2020-12-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.099 Å) 主引用文献 Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
7B0G	TgoT_6G12 binary with 2 hCTPs 分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(P*AP*TP*TP*GP*GP*CP*TP*GP*CP*CP*CP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*GP*GP*GP*CP*AP*GP*()P*())-3'), ... 著者 Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. 登録日 2020-11-19 公開日 2020-12-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
7B0F	TgoT_6G12 Binary complex 分子名称: DNA (5'-D(P*AP*AP*CP*GP*GP*CP*TP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ... 著者 Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. 登録日 2020-11-19 公開日 2020-12-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.797 Å) 主引用文献 Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020

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