3S0P
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6FLH
| Monomeric Human Cu,Zn Superoxide dismutase, SOD1 7+7, apo form | 分子名称: | GLYCEROL, SULFATE ION, Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Yang, F, Logan, D, Oliveberg, M. | 登録日 | 2018-01-25 | 公開日 | 2018-11-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | The Cost of Long Catalytic Loops in Folding and Stability of the ALS-Associated Protein SOD1. J.Am.Chem.Soc., 140, 2018
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6FFK
| Human apo-SOD1 bound to PtCl2(1R,2R-1,4-DACH | 分子名称: | PtCl2(1(R),2(R)-DACH), Superoxide dismutase [Cu-Zn] | 著者 | Calderone, V, Nativi, C, Cantini, F, Di Cesare Mannelli, L. | 登録日 | 2018-01-08 | 公開日 | 2018-11-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Interaction of Half Oxa-/Halfcis-Platin Complex with Human Superoxide Dismutase and Induced Reduction of Neurotoxicity. ACS Med Chem Lett, 9, 2018
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5YTU
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6FOI
| Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Wright, G.S.A, Sala, F.A, Antonyuk, S.V, Garratt, R.C, Hasnain, S.S. | 登録日 | 2018-02-07 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS. Plos Biol., 17, 2019
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6FN8
| Domain II of the HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE at 1.55 A resolution | 分子名称: | Copper chaperone for superoxide dismutase, ZINC ION | 著者 | Sala, F.A, Wright, G.S.A, Antonyuk, S.V, Garratt, R.C, Hasnain, S.S. | 登録日 | 2018-02-02 | 公開日 | 2019-01-30 | 最終更新日 | 2019-06-19 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS. Plos Biol., 17, 2019
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5YTO
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5YUL
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6A9O
| Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis | 分子名称: | 2'-[(6-oxo-5,6-dihydrophenanthridin-3-yl)carbamoyl][1,1'-biphenyl]-2-carboxylic acid, DIMETHYL SULFOXIDE, Dihydrogen tetrasulfide, ... | 著者 | Manjula, R, Padmanabhan, B. | 登録日 | 2018-07-14 | 公開日 | 2019-07-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis. J.Biomol.Struct.Dyn., 37, 2019
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2GBV
| C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase | 分子名称: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Hornberg, A, Logan, D.T, Marklund, S.L, Oliveberg, M. | 登録日 | 2006-03-11 | 公開日 | 2007-01-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase J.Mol.Biol., 365, 2007
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2JCW
| REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE | 分子名称: | COPPER (I) ION, CU/ZN SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D. | 登録日 | 1998-12-21 | 公開日 | 1999-06-08 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A structure-based mechanism for copper-zinc superoxide dismutase. Biochemistry, 38, 1999
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2GBT
| C6A/C111A CuZn Superoxide dismutase | 分子名称: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Hornberg, A, Logan, D.T, Marklund, S.L, Oliveberg, M. | 登録日 | 2006-03-11 | 公開日 | 2007-01-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase J.Mol.Biol., 365, 2007
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2GBU
| C6A/C111A/C57A/C146A apo CuZn Superoxide dismutase | 分子名称: | Superoxide dismutase [Cu-Zn] | 著者 | Hornberg, A, Logan, D.T, Marklund, S.L, Oliveberg, M. | 登録日 | 2006-03-11 | 公開日 | 2007-01-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase J.Mol.Biol., 365, 2007
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2JLP
| Crystal structure of human extracellular copper-zinc superoxide dismutase. | 分子名称: | COPPER (II) ION, EXTRACELLULAR SUPEROXIDE DISMUTASE (CU-ZN), THIOCYANATE ION, ... | 著者 | Antonyuk, S.V, Strange, R.W, Marklund, S.L, Hasnain, S.S. | 登録日 | 2008-09-14 | 公開日 | 2009-03-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Structure of Human Extracellular Copper-Zinc Superoxide Dismutase at 1.7 A Resolution: Insights Into Heparin and Collagen Binding. J.Mol.Biol., 388, 2009
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7VZF
| Cryo-EM structure of amyloid fibril formed by full-length human SOD1 | 分子名称: | Superoxide dismutase [Cu-Zn] | 著者 | Wang, L.Q, Ma, Y.Y, Yuan, H.Y, Zhao, K, Zhang, M.Y, Wang, Q, Huang, X, Xu, W.C, Chen, J, Li, D, Zhang, D.L, Zou, L.Y, Yin, P, Liu, C, Liang, Y. | 登録日 | 2021-11-16 | 公開日 | 2022-06-29 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion. Nat Commun, 13, 2022
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6SPH
| A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 WITH EBSELEN BOND IN C2 SPACE GROUP | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, N-phenyl-2-selanylbenzamide, ... | 著者 | Shahid, M, Chantadul, V, Amporndanai, K, Wright, G, Antonyuk, S, Hasnain, S. | 登録日 | 2019-09-01 | 公開日 | 2020-03-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy. Commun Biol, 3, 2020
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8IQ1
| Crystal structure of hydrogen sulfide-bound superoxide dismutase in reduced state | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ... | 著者 | Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C. | 登録日 | 2023-03-15 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme. Cell Rep, 42, 2023
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3CE1
| Crystal Structure of the Cu/Zn Superoxide Dismutase from Cryptococcus liquefaciens Strain N6 | 分子名称: | ACETATE ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Teh, A.H, Kanamasa, S, Kajiwara, S, Kumasaka, T. | 登録日 | 2008-02-27 | 公開日 | 2008-08-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure of Cu/Zn superoxide dismutase from the heavy-metal-tolerant yeast Cryptococcus liquefaciens strain N6. Biochem.Biophys.Res.Commun., 374, 2008
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3CQQ
| Human SOD1 G85R Variant, Structure II | 分子名称: | ACETYL GROUP, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Cao, X, Antonyuk, S, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J. | 登録日 | 2008-04-03 | 公開日 | 2008-04-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis. J.Biol.Chem., 283, 2008
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8JD8
| Crystal structure of Citrus limon Cu-Zn superoxide dismutase | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Utami, R.A, Yoshida, H, Retnoningrum, D.S, Ismaya, W.T. | 登録日 | 2023-05-12 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon. Acta Crystallogr.,Sect.F, 79, 2023
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3CQP
| Human SOD1 G85R Variant, Structure I | 分子名称: | COPPER (II) ION, MALONATE ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Cao, X, Antonyuk, S, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J. | 登録日 | 2008-04-03 | 公開日 | 2008-04-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis. J.Biol.Chem., 283, 2008
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7WWY
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7WWT
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7WX0
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7WX1
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