8UFB
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8EM7
| Cryo-EM structure of LRP2 at pH 5.2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Beenken, A, Cerutti, G, Fitzpatrick, A.W, Barasch, J, Shapiro, L. | 登録日 | 2022-09-27 | 公開日 | 2023-02-08 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structures of LRP2 reveal a molecular machine for endocytosis. Cell, 186, 2023
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8EM4
| Cryo-EM structure of LRP2 at pH 7.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Beenken, A, Cerutti, G, Brasch, J, Fitzpatrick, A.W, Barasch, J, Shapiro, L. | 登録日 | 2022-09-26 | 公開日 | 2023-02-08 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structures of LRP2 reveal a molecular machine for endocytosis. Cell, 186, 2023
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6CXO
| Complement component-9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ... | 著者 | Law, R.H.P, Spicer, B.A, Caradoc-Davies, T.T. | 登録日 | 2018-04-03 | 公開日 | 2018-09-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018
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6DLW
| Complement component polyC9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose | 著者 | Dunstone, M.A, Spicer, B.A, Law, R.H.P. | 登録日 | 2018-06-03 | 公開日 | 2018-09-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018
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3OJY
| Crystal Structure of Human Complement Component C8 | 分子名称: | CALCIUM ION, Complement component C8 alpha chain, Complement component C8 beta chain, ... | 著者 | Lovelace, L.L, Cooper, C.L, Sodetz, J.M, Lebioda, L. | 登録日 | 2010-08-23 | 公開日 | 2011-04-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement. J.Biol.Chem., 286, 2011
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3P5C
| The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation | 分子名称: | CALCIUM ION, Low density lipoprotein receptor variant, Proprotein convertase subtilisin/kexin type 9 | 著者 | Lo Surdo, P, Bottomley, M.J, Calzetta, A, Settembre, E.C, Cirillo, A, Pandit, S, Ni, Y, Hubbard, B, Sitlani, A, Carfi, A. | 登録日 | 2010-10-08 | 公開日 | 2011-10-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH. Embo Rep., 12, 2011
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7QBG
| TC:CD320 in complex with nanobody TC-Nb4 | 分子名称: | Anti-TC:CD320 nanobody TC-Nb4, CALCIUM ION, CD320 antigen, ... | 著者 | Bloch, J.S, Locher, K.P. | 登録日 | 2021-11-19 | 公開日 | 2022-03-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Generation of nanobodies targeting the human, transcobalamin-mediated vitamin B 12 uptake route. Faseb J., 36, 2022
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4ZRQ
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7QBE
| TC:CD320 in complex with nanobody TC-Nb11 | 分子名称: | Anti-transcobalamin-2 nanobody TC-Nb11, CALCIUM ION, CD320 antigen, ... | 著者 | Bloch, J.S, Locher, K.P. | 登録日 | 2021-11-19 | 公開日 | 2022-03-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Generation of nanobodies targeting the human, transcobalamin-mediated vitamin B 12 uptake route. Faseb J., 36, 2022
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7QBD
| TC:CD320 in complex with nanobody TC-Nb26 | 分子名称: | Antitranscobalamin-nanobody TC-Nb26, CALCIUM ION, CD320 antigen, ... | 著者 | Bloch, J.S, Locher, K.P. | 登録日 | 2021-11-19 | 公開日 | 2022-03-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (4.18 Å) | 主引用文献 | Generation of nanobodies targeting the human, transcobalamin-mediated vitamin B 12 uptake route. Faseb J., 36, 2022
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7QBF
| TC:CD320 in complex with nanobody TC-Nb34 | 分子名称: | 1,2-ETHANEDIOL, Anti-transcobalamin-2 nanobody TC-Nb34, CALCIUM ION, ... | 著者 | Bloch, J.S, Locher, K.P. | 登録日 | 2021-11-19 | 公開日 | 2022-03-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Generation of nanobodies targeting the human, transcobalamin-mediated vitamin B 12 uptake route. Faseb J., 36, 2022
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4ZRP
| TC:CD320 | 分子名称: | CALCIUM ION, CD320 antigen, CYANOCOBALAMIN, ... | 著者 | Alam, A, Locher, K.P. | 登録日 | 2015-05-12 | 公開日 | 2016-07-20 | 最終更新日 | 2021-08-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of transcobalamin recognition by human CD320 receptor. Nat Commun, 7, 2016
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7WQX
| Structure of Inactive-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WQW
| Structure of Active-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WR7
| Structure of Inhibited-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, Enteropeptidase catalytic light chain, ... | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WQZ
| Structure of Active-mutEP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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5B4X
| Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low density lipoprotein receptor-related protein 8, ... | 著者 | Yasui, N, Hirai, H, Yamashita, K, Takagi, J, Nogi, T. | 登録日 | 2016-04-20 | 公開日 | 2017-04-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand. To Be Published
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2KRI
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7F57
| Kainate-bound GluK2-1xNeto2 complex, at the desensitized state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, kainate 2, ... | 著者 | He, L.L, Gao, Y.W, Li, B, Zhao, Y. | 登録日 | 2021-06-21 | 公開日 | 2021-09-29 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Kainate receptor modulation by NETO2. Nature, 599, 2021
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7F56
| DNQX-bound GluK2-1xNeto2 complex, with asymmetric LBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, kainate 2, ... | 著者 | He, L.L, Gao, Y.W, Li, B, Zhao, Y. | 登録日 | 2021-06-21 | 公開日 | 2021-09-29 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Kainate receptor modulation by NETO2. Nature, 599, 2021
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7F5A
| DNQX-bound GluK2-2xNeto2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, kainate 2, ... | 著者 | He, L.L, Gao, Y.W, Li, B, Zhao, Y. | 登録日 | 2021-06-21 | 公開日 | 2021-09-29 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Kainate receptor modulation by NETO2. Nature, 599, 2021
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7F59
| DNQX-bound GluK2-1xNeto2 complex | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | He, L.L, Gao, Y.W, Li, B, Zhao, Y. | 登録日 | 2021-06-21 | 公開日 | 2021-09-29 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Kainate receptor modulation by NETO2. Nature, 599, 2021
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7F5B
| LBD-TMD focused reconstruction of DNQX-bound GluK2-1xNeto2 complex | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | He, L.L, Gao, Y.W, Li, B, Zhao, Y. | 登録日 | 2021-06-21 | 公開日 | 2021-09-29 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Kainate receptor modulation by NETO2. Nature, 599, 2021
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7FFL
| Cryo-EM structure of VEEV VLP-LDLRAD3-D1 complex at the 2-fold axes | 分子名称: | CALCIUM ION, Capsid protein, Low-density lipoprotein receptor class A domain-containing protein 3, ... | 著者 | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | 登録日 | 2021-07-23 | 公開日 | 2021-10-20 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
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