8H40
| Cryo-EM structure of the transcription activation complex NtcA-TAC | 分子名称: | DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. | 登録日 | 2022-10-09 | 公開日 | 2023-10-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
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8H3V
| Cryo-EM structure of the full transcription activation complex NtcA-NtcB-TAC | 分子名称: | DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. | 登録日 | 2022-10-09 | 公開日 | 2023-10-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
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8EVC
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8EVB
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8EVA
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8EV9
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8EV8
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8EUC
| Cryo-EM structure of cGMP bound human CNGA3/CNGB3 channel in GDN, transition state 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... | 著者 | Hu, Z, Zheng, X, Yang, J. | 登録日 | 2022-10-18 | 公開日 | 2023-08-09 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
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8EU3
| Cryo-EM structure of cGMP bound human CNGA3/CNGB3 channel in GDN, transition state 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... | 著者 | Hu, Z, Zheng, X, Yang, J. | 登録日 | 2022-10-18 | 公開日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
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8ETP
| Cryo-EM structure of cGMP bound closed state of human CNGA3/CNGB3 channel in GDN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ... | 著者 | Hu, Z, Zheng, X, Yang, J. | 登録日 | 2022-10-17 | 公開日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Commun, 14, 2023
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8EP1
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8EP0
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8EOW
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8EM8
| Co-crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium falciparum in complex with RY-1-165 | 分子名称: | UNKNOWN ATOM OR ION, [(3R)-3-{[(4M)-4-(4-cyclopropyl-2-phenyl-1H-imidazol-1-yl)pyrimidin-2-yl]amino}pyrrolidin-1-yl](1,3-thiazol-2-yl)methanone, cGMP-dependent protein kinase, ... | 著者 | Hutchinson, A, Dong, A, Seitova, A, Bhanot, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2022-09-27 | 公開日 | 2022-11-02 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials. J.Med.Chem., 67, 2024
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8BX7
| Structure of the rod CNG channel bound to calmodulin | 分子名称: | Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1, calmodulin-1 | 著者 | Marino, J. | 登録日 | 2022-12-08 | 公開日 | 2023-04-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel. Proc.Natl.Acad.Sci.USA, 120, 2023
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7YIJ
| Human KCNH5 pore dilation but the non-conducting state | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | 著者 | Zhang, M.F. | 登録日 | 2022-07-16 | 公開日 | 2023-04-05 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
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7YIH
| Human KCNH5 open state | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | 著者 | Zhang, M.F. | 登録日 | 2022-07-16 | 公開日 | 2023-04-05 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
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7YIG
| Human KCNH5 pre-open state 2 | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | 著者 | Zhang, M.F. | 登録日 | 2022-07-16 | 公開日 | 2023-04-05 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
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7YIF
| Human KCNH5 pre-open state 1 | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | 著者 | Zhang, M.F. | 登録日 | 2022-07-16 | 公開日 | 2023-04-05 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
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7YIE
| Human KCNH5-closed state 2 | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | 著者 | Zhang, M.F. | 登録日 | 2022-07-16 | 公開日 | 2023-04-05 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
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7YID
| Human KCNH5 closed state 1 | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 | 著者 | Zhang, M.F. | 登録日 | 2022-07-16 | 公開日 | 2023-04-05 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
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7XUF
| Cryo-EM structure of the AKT1-AtKC1 complex from Arabidopsis thaliana | 分子名称: | POTASSIUM ION, Potassium channel AKT1, Potassium channel KAT3 | 著者 | Yang, G.H, Lu, Y.M, Jia, Y.T, Yang, F, Zhang, Y.M, Xu, X, Li, X.M, Lei, J.L. | 登録日 | 2022-05-18 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis. Nat Commun, 13, 2022
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7WSW
| Cryo-EM structure of the Potassium channel AKT1 from Arabidopsis thaliana | 分子名称: | PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1 | 著者 | Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L. | 登録日 | 2022-02-02 | 公開日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis. Nat Commun, 13, 2022
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7WM2
| Cryo-EM structure of AKT1 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium channel AKT1 | 著者 | Dongliang, L, Zijie, Z, Yannan, Q, Yuyue, T, Huaizong, S. | 登録日 | 2022-01-14 | 公開日 | 2023-01-25 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | 主引用文献 | Structural basis for the regulation mechanism of a hyperpolarization-activated K+ channel AKT1 by AtKC1 To Be Published
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7WM1
| Cryo-EM structure of AKT1-AtKC1 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium channel AKT1, ... | 著者 | Dongliang, L, Zijie, Z, Yannan, Q, Yuyue, T, Huaizong, S. | 登録日 | 2022-01-14 | 公開日 | 2023-01-25 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for the regulation mechanism of a hyper polarization-activated K+ channel AKT1 by AtKC1 To Be Published
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