3OJP
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![BU of 3ojp by Molmil](/molmil-images/mine/3ojp) | D52N Mutant of Hen Egg White Lysozyme (HEWL) | 分子名称: | ACETATE ION, CHLORIDE ION, Lysozyme C, ... | 著者 | O'Meara, F, Bradley, J, O'Rourke, P.E, Webb, H, Tynan-Connolly, B.M, Nielsen, J.E. | 登録日 | 2010-08-23 | 公開日 | 2011-03-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | D52N Mutant of Hen Egg White Lysozyme (HEWL) TO BE PUBLISHED
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3B9X
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7XAF
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![BU of 7xaf by Molmil](/molmil-images/mine/7xaf) | The crystal structure of TrkA kinase in complex with 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo- tetradecaphan-2-yne-45-carboxamide | 分子名称: | 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo-tetradecaphan-2-yne-45-carboxamide, High affinity nerve growth factor receptor | 著者 | Zhang, Z.M, Wang, Y.J. | 登録日 | 2022-03-17 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.001182 Å) | 主引用文献 | Discovery of the First Highly Selective and Broadly Effective Macrocycle-Based Type II TRK Inhibitors that Overcome Clinically Acquired Resistance. J.Med.Chem., 65, 2022
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3B2K
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![BU of 3b2k by Molmil](/molmil-images/mine/3b2k) | Iodide derivative of human LFABP | 分子名称: | Fatty acid-binding protein, liver, IODIDE ION, ... | 著者 | Sharma, A, Yogavel, M, Sharma, A. | 登録日 | 2011-08-03 | 公開日 | 2012-06-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
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3B4Y
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![BU of 3b4y by Molmil](/molmil-images/mine/3b4y) | FGD1 (Rv0407) from Mycobacterium tuberculosis | 分子名称: | CITRATE ANION, COENZYME F420, PROBABLE F420-DEPENDENT GLUCOSE-6-PHOSPHATE DEHYDROGENASE FGD1 | 著者 | Bashiri, G, Squire, C.J, Moreland, N.M, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2007-10-25 | 公開日 | 2008-04-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding J.Biol.Chem., 283, 2008
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3B8I
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3P0X
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3B2H
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![BU of 3b2h by Molmil](/molmil-images/mine/3b2h) | Iodide derivative of human LFABP at high resolution | 分子名称: | Fatty acid-binding protein, liver, IODIDE ION, ... | 著者 | Sharma, A, Yogavel, M, Sharma, A. | 登録日 | 2011-08-03 | 公開日 | 2012-06-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
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3P67
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3P7X
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![BU of 3p7x by Molmil](/molmil-images/mine/3p7x) | Crystal structure of an atypical two-cysteine peroxiredoxin (SAOUHSC_01822) from Staphylococcus aureus NCTC8325 | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Probable thiol peroxidase, ... | 著者 | Bhattacharyya, S, Dutta, D, Ghosh, A.K, Das, A.K. | 登録日 | 2010-10-13 | 公開日 | 2011-10-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal structure of an atypical two-cysteine peroxiredoxin (SAOUHSC_01822) from Staphylococcus aureus NCTC8325 To be Published
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4N1R
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3OYX
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![BU of 3oyx by Molmil](/molmil-images/mine/3oyx) | Haloferax volcanii Malate Synthase Magnesium/Glyoxylate Complex | 分子名称: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | 著者 | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | 登録日 | 2010-09-24 | 公開日 | 2011-06-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
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4MSN
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![BU of 4msn by Molmil](/molmil-images/mine/4msn) | Crystal structure of PDE10A2 with fragment ZT0451 (8-nitroquinoline) | 分子名称: | 8-nitroquinoline, NICKEL (II) ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 著者 | Sridhar, V, Badger, J, Logan, C, Chie-Leon, B, Nienaber, V. | 登録日 | 2013-09-18 | 公開日 | 2014-05-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography. J Biomol Screen, 19, 2014
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3BQB
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![BU of 3bqb by Molmil](/molmil-images/mine/3bqb) | Hexagonal kristal form of 2-keto-3-deoxyarabinonate dehydratase | 分子名称: | MAGNESIUM ION, Putative uncharacterized protein | 著者 | Barends, T.M, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L. | 登録日 | 2007-12-20 | 公開日 | 2008-04-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily J.Mol.Biol., 379, 2008
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4N9A
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![BU of 4n9a by Molmil](/molmil-images/mine/4n9a) | E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid | 分子名称: | (1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-10-19 | 公開日 | 2013-11-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
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3P4U
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![BU of 3p4u by Molmil](/molmil-images/mine/3p4u) | Crystal structure of active caspase-6 in complex with Ac-VEID-CHO inhibitor | 分子名称: | Ac-VEID-CHO inhibitor, Caspase-6 | 著者 | Mueller, I, Lamers, M.B.A.C, Ritchie, A.J, Dominguez, C, Munoz, I, Maillard, M, Kiselyov, A. | 登録日 | 2010-10-07 | 公開日 | 2011-09-28 | 最終更新日 | 2015-12-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of active and inhibitor-bound human Casp6 To be Published
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4N1E
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![BU of 4n1e by Molmil](/molmil-images/mine/4n1e) | Structural evidence for antigen receptor evolution | 分子名称: | Lysozyme C, immunoglobulin variable light chain domain | 著者 | Langley, D.B, Rouet, R, Stock, D, Christ, D. | 登録日 | 2013-10-04 | 公開日 | 2014-10-29 | 最終更新日 | 2018-04-18 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Structural reconstruction of protein ancestry. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3ONK
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![BU of 3onk by Molmil](/molmil-images/mine/3onk) | yeast Ent3_ENTH domain | 分子名称: | Epsin-3 | 著者 | Wang, J, Fang, P, Niu, L, Teng, M. | 登録日 | 2010-08-29 | 公開日 | 2011-07-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Epsin N-terminal homology domains bind on opposite sides of two SNAREs Proc.Natl.Acad.Sci.USA, 108, 2011
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4N30
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6T38
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![BU of 6t38 by Molmil](/molmil-images/mine/6t38) | Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, CHLORIDE ION, ... | 著者 | Alphey, M.S, Xiao, G, Westwood, J.N. | 登録日 | 2019-10-10 | 公開日 | 2020-08-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Next generation Glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: An extended SAR study to direct future design. Bioorg.Med.Chem., 50, 2021
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3ATI
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![BU of 3ati by Molmil](/molmil-images/mine/3ati) | Crystal structure of trypsin complexed with (3-methoxyphenyl)methanamine | 分子名称: | 1-(3-methoxyphenyl)methanamine, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Tanaka, I. | 登録日 | 2011-01-05 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
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3ATM
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![BU of 3atm by Molmil](/molmil-images/mine/3atm) | Crystal structure of trypsin complexed with 2-(1H-indol-3-yl)ethanamine | 分子名称: | 2-(1H-INDOL-3-YL)ETHANAMINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Tanaka, I. | 登録日 | 2011-01-05 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
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3OYZ
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![BU of 3oyz by Molmil](/molmil-images/mine/3oyz) | Haloferax volcanii Malate Synthase Pyruvate/Acetyl-CoA Ternary Complex | 分子名称: | ACETYL COENZYME *A, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | 登録日 | 2010-09-24 | 公開日 | 2011-06-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
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3P45
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![BU of 3p45 by Molmil](/molmil-images/mine/3p45) | Crystal structure of apo-caspase-6 at physiological pH | 分子名称: | caspase-6 | 著者 | Mueller, I, Lamers, M.B.A.C, Ritchie, A.J, Dominguez, C, Munoz, I, Maillard, M, Kiselyov, A. | 登録日 | 2010-10-06 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Crystal structures of active and inhibitor-bound human Casp6 To be Published
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4M4N
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