PDB: 98225 件ウェブページステータス検索Chemie searchBIRD

---

6O81	Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to translation initiation factor 2 from Homo sapiens 分子名称: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ... 著者 Nguyen, H, Kenner, L, Frost, A. 登録日 2019-03-08 公開日 2019-05-15 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Science, 364, 2019
6AK8	Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Ca-8oxodGTP 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Chang, Y.K, Wu, W.J, Tsai, M.D. 登録日 2018-08-30 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6AK9	Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Cytosine and Incoming Ca-8oxodGTP 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Chang, Y.K, Wu, W.J, Tsai, M.D. 登録日 2018-08-30 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6AKH	Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Mn-dUMPNPP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Chang, Y.K, Wu, W.J, Tsai, M.D. 登録日 2018-08-31 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
5LZU	Structure of the mammalian ribosomal termination complex with accommodated eRF1 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
6W2T	Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the closed state (Class 2) 分子名称: 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ... 著者 Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S. 登録日 2020-03-08 公開日 2020-04-22 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate. Elife, 9, 2020
1CD2	LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COMPLEXES WITH FOLATE AND NADP+ 分子名称: DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A. 登録日 1999-03-05 公開日 2000-03-06 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+. Biochemistry, 38, 1999
4L8A	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in ternary complex with N-Phenylacetyl-Gly-AcLys and CoA 分子名称: 1,2-ETHANEDIOL, COENZYME A, N-(phenylacetyl)glycyl-N~6~-acetyl-L-lysine, ... 著者 Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2013-06-16 公開日 2013-07-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa. J.Biol.Chem., 288, 2013
6YAN	Mammalian 48S late-stage translation initiation complex with histone 4 mRNA 分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... 著者 Bochler, A, Simonetti, A, Guca, E, Hashem, Y. 登録日 2020-03-12 公開日 2020-04-08 最終更新日 2020-04-22 実験手法 ELECTRON MICROSCOPY (3.48 Å) 主引用文献 Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
6YAL	Mammalian 48S late-stage initiation complex with beta-globin mRNA 分子名称: 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ... 著者 Bochler, A, Simonetti, A, Guca, E, Hashem, Y. 登録日 2020-03-12 公開日 2020-04-08 最終更新日 2020-04-22 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
1DXY	STRUCTURE OF D-2-HYDROXYISOCAPROATE DEHYDROGENASE 分子名称: 2-OXO-4-METHYLPENTANOIC ACID, D-2-HYDROXYISOCAPROATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Dengler, U, Niefind, K, Kiess, M, Schomburg, D. 登録日 1996-08-13 公開日 1997-06-16 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution. J.Mol.Biol., 267, 1997
3FWQ	Inactive conformation of human protein kinase CK2 catalytic subunit 分子名称: CHLORIDE ION, Casein kinase II subunit alpha, GLYCEROL, ... 著者 Niefind, K, Raaf, J, Issinger, O.G. 登録日 2009-01-19 公開日 2009-02-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 First inactive conformation of CK2 alpha, the catalytic subunit of protein kinase CK2 J.Mol.Biol., 386, 2009
7ASE	43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase 分子名称: 18S, 40S ribosomal protein S10, putative, ... 著者 Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. 登録日 2020-10-27 公開日 2021-04-14 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
8RG0	Structure of human eIF3 core from closed 48S translation initiation complex 分子名称: 18S rRNA, 40S ribosomal protein S13, 40S ribosomal protein S14, ... 著者 Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. 登録日 2023-12-13 公開日 2024-08-14 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for translational control by the human 48S initiation complex. Nat.Struct.Mol.Biol., 2024
7RLO	Structure of the human eukaryotic translation initiation factor 2B (eIF2B) in complex with a viral protein NSs 分子名称: Non-structural protein NS-S, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... 著者 Wang, L, Schoof, M, Cogan, J, Lawrence, R, Boone, M, Wuerth, J, Frost, M, Walter, P. 登録日 2021-07-26 公開日 2021-12-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B. Nat Commun, 12, 2021
5AC0	ovis aries Aldehyde Dehydrogenase 1A1 in complex with a duocarmycin analog 分子名称: 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Koch, M.F, Harteis, S, Blank, I.D, Pestel, G, Tietze, L.F, Ochsenfeld, C, Schneider, S, Sieber, S.A. 登録日 2015-08-10 公開日 2015-08-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues. Angew.Chem.Int.Ed.Engl., 54, 2015
5HWP	MvaS with acetylated Cys115 in complex with coenzyme A 分子名称: COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... 著者 Bock, T, Kasten, J, Blankenfeldt, W. 登録日 2016-01-29 公開日 2016-05-11 最終更新日 2016-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
6AS7	CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN DNA-PRIMED DNA TEMPLATE AND DCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*AP*GP*GP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), ... 著者 Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. 登録日 2017-08-23 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Activity and fidelity of human DNA polymerase alpha depend on primer structure. J. Biol. Chem., 293, 2018
4WL0	Ligand-free structure of human platelet phosphofructokinase in an R-state, crystal form I 分子名称: ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION 著者 Kloos, M, Strater, N. 登録日 2014-10-05 公開日 2015-06-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem.J., 469, 2015
3D89	Crystal Structure of a Soluble Rieske Ferredoxin from Mus musculus 分子名称: 1,2-ETHANEDIOL, FE2/S2 (INORGANIC) CLUSTER, Rieske domain-containing protein 著者 Levin, E.J, McCoy, J.G, Elsen, N.L, Seder, K.D, Bingman, C.A, Wesenberg, G.E, Fox, B.G, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2008-05-22 公開日 2008-07-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.071 Å) 主引用文献 X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus. Acta Crystallogr.,Sect.D, 64, 2008
5HWR	MvaS in complex with coenzyme A 分子名称: COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... 著者 Bock, T, Kasten, J, Blankenfeldt, W. 登録日 2016-01-29 公開日 2016-05-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
5HWQ	MvaS in complex with acetoacetyl coenzyme A 分子名称: ACETOACETYL-COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... 著者 Bock, T, Kasten, J, Blankenfeldt, W. 登録日 2016-01-29 公開日 2016-05-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
8S8E	Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-3.1) 分子名称: 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... 著者 Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. 登録日 2024-03-06 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.85 Å) 主引用文献 Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
5ABU	Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog 分子名称: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, CHLORIDE ION, ... 著者 Peter, D, Weichenrieder, O. 登録日 2015-08-09 公開日 2015-09-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation Genes Dev., 29, 2015
5A8L	Human eRF1 and the hCMV nascent peptide in the translation termination complex 分子名称: 28S RIBOSOMAL RNA, 60S RIBOSOMAL PROTEIN L12, 60S RIBOSOMAL PROTEIN L17, ... 著者 Matheisl, S, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2015-07-16 公開日 2015-12-02 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of a Human Translation Termination Complex. Nucleic Acids Res., 43, 2015

<287288289290291292293294295296297298299300301302>