PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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4R56	Crystal structure of Sulfolobus Cren7-dsDNA(GTGATCAC) complex 分子名称: Chromatin protein Cren7, DNA (5'-D(*GP*TP*GP*AP*TP*CP*AP*C)-3') 著者 Zhang, Z.F, Gong, Y, Chen, Y.Y, Li, H.B, Huang, L. 登録日 2014-08-20 公開日 2015-08-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insights into the interaction between Cren7 and DNA: the role of loop beta 3-beta 4 Extremophiles, 19, 2015
4Q2N	INADL PDZ3 in Complex with a Phage-Derived Peptide 分子名称: 1,2-ETHANEDIOL, InaD-like protein 著者 Appleton, B.A, Wiesmann, C. 登録日 2014-04-09 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A structural portrait of the PDZ domain family. J.Mol.Biol., 426, 2014
4QH3	X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II) 分子名称: Ribonuclease pancreatic, bis(chloranyl)-(dimethylamino)-(methylamino)platinum 著者 Russo Krauss, I, Merlino, A. 登録日 2014-05-26 公開日 2014-07-30 最終更新日 2014-08-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Interactions between Anticancer trans-Platinum Compounds and Proteins: Crystal Structures and ESI-MS Spectra of Two Protein Adducts of trans-(Dimethylamino)(methylamino)dichloridoplatinum(II). Inorg.Chem., 53, 2014
6OPB	Structure of Aedes aegypti OBP22 in the complex with arachidic acid 分子名称: AAEL005772-PA, DIMETHYL SULFOXIDE, icosanoic acid 著者 Jones, D.N, Wang, J. 登録日 2019-04-24 公開日 2019-05-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. Sci Rep, 10, 2020
6PTP	Joint X-ray/neutron structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with tetrahedral intermediate mimic KVS-1 分子名称: HIV-1 Protease, N~2~-[(2R,5S)-5-({(2S,3S)-2-[(N-acetyl-L-threonyl)amino]-3-methylpent-4-enoyl}amino)-2-butyl-4,4-dihydroxynonanoyl]-L-glutaminyl-L-argininamide 著者 Kovalevsky, A, Das, A. 登録日 2019-07-16 公開日 2020-06-10 最終更新日 2023-10-25 実験手法 NEUTRON DIFFRACTION (1.85 Å), X-RAY DIFFRACTION 主引用文献 Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design. Acs Omega, 5, 2020
4RFM	ITK kinase domain in complex with compound 1 N-{1-[(1,1-dioxo-1-thian-2-yl)(phenyl)methyl]-1H- pyrazol-4-yl}-5,5-difluoro-5a-methyl-1H,4H,4aH,5H,5aH,6H-cyclopropa[f]indazole-3-carboxamide 分子名称: (4aS,5aR)-N-{1-[(R)-[(2R)-1,1-dioxidotetrahydro-2H-thiopyran-2-yl](phenyl)methyl]-1H-pyrazol-4-yl}-5,5-difluoro-5a-methyl-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK 著者 McEwan, P.A, Barker, J.J, Eigenbrot, C. 登録日 2014-09-26 公開日 2015-04-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo. J.Med.Chem., 58, 2015
4QQ8	Crystal structure of the formolase FLS in space group P 43 21 2 分子名称: 1,2-ETHANEDIOL, Formolase, MAGNESIUM ION, ... 著者 Shen, B.W, Siegel, J.B, Stoddard, B.L. 登録日 2014-06-26 公開日 2015-03-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Computational protein design enables a novel one-carbon assimilation pathway. Proc.Natl.Acad.Sci.USA, 112, 2015
4REE	Crystal Structure of TR3 LBD in complex with Molecule 6 分子名称: 1-(2,3,4-trihydroxyphenyl)nonan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1 著者 Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W. 登録日 2014-09-22 公開日 2015-09-09 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity Chem.Biol., 22, 2015
4P9N	Crystal structure of sshesti PE mutant 分子名称: Carboxylesterase 著者 Unno, H. 登録日 2014-04-04 公開日 2014-07-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Insights into the Low pH Adaptation of a Unique Carboxylesterase from Ferroplasma: ALTERING THE pH OPTIMA OF TWO CARBOXYLESTERASES. J.Biol.Chem., 289, 2014
4REF	Crystal Structure of TR3 LBD_L449W in complex with Molecule 2 分子名称: 1-(3,4,5-trihydroxyphenyl)hexan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1 著者 Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W. 登録日 2014-09-22 公開日 2015-09-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity Chem.Biol., 22, 2015
4R6F	Crystal structure of computational designed protein DLRR_I 分子名称: Leucine rich repeat DLRR_I 著者 Shen, B.W, Stoddard, B.L. 登録日 2014-08-25 公開日 2015-01-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Control of repeat-protein curvature by computational protein design. Nat.Struct.Mol.Biol., 22, 2015
6VZK	Crystal structure of human CaMKII-alpha (CAMK2A)kinase domain 分子名称: 4'-HYDROXYCINNAMIC ACID, Calcium/calmodulin-dependent protein kinase type II subunit alpha 著者 Ozden, C, Stratton, M.M, Garman, S.C. 登録日 2020-02-28 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Characterization of CaMKII alpha holoenzyme stability. Protein Sci., 29, 2020
6O9X	Structure of human PARG complexed with JA2-4 分子名称: 1,3-dimethyl-8-{[2-(pyrrolidin-1-yl)ethyl]sulfanyl}-6-sulfanylidene-1,3,6,9-tetrahydro-2H-purin-2-one, Poly(ADP-ribose) glycohydrolase 著者 Stegeman, R.A, Jones, D.E, Ellenberger, T, Kim, I.K, Tainer, J.A. 登録日 2019-03-15 公開日 2019-12-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nat Commun, 10, 2019
6OA1	Structure of human PARG complexed with JA2120 分子名称: 1,3-dimethyl-8-{[2-(morpholin-4-yl)ethyl]sulfanyl}-3,7-dihydro-1H-purine-2,6-dione, Poly(ADP-ribose) glycohydrolase 著者 Stegeman, R.A, Jones, D.E, Ellenberger, T, Kim, I.K, Tainer, J.A. 登録日 2019-03-15 公開日 2019-12-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nat Commun, 10, 2019
4PO3	Crystal structure of a C4-C4 SN3 tributyrin phosphonate inhibited by ESTERASE B from LACTOBACILLUS RHAMNOSIS 分子名称: (2R)-2,3-dibutoxypropyl hydrogen (S)-propylphosphonate, Esterase B 著者 Bennett, M.D, Anderson, B.F, Norris, G.E, Colbert, D.A. 登録日 2014-02-24 公開日 2014-06-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal structure of a C4-C4 SN3 tributyrin phodphonate inhibited ESTERASE B from LACTOBACILLUS RHAMNOSIS TO BE PUBLISHED
6OKE	Crystal structure of an apo Transferrin-Receptor-Binding cystine-dense peptide 分子名称: Transferrin-Receptor Binding Peptide 著者 Rupert, P.B, Strong, R.K. 登録日 2019-04-12 公開日 2020-04-15 最終更新日 2020-07-08 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules. J.Mol.Biol., 432, 2020
4P77	Structure of ribB complexed with substrate Ru5P 分子名称: 3,4-dihydroxy-2-butanone 4-phosphate synthase, GLYCEROL, RIBULOSE-5-PHOSPHATE 著者 Islam, Z, Kumar, A, Singh, S, Salmon, L, Karthikeyan, S. 登録日 2014-03-26 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae. J.Biol.Chem., 290, 2015
4PNW	E. coli sliding clamp in complex with (R)-6-bromo-9-(2-((S)-1-carboxy-2-phenylethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid 分子名称: (2R)-6-bromo-9-(2-{[(1S)-1-carboxy-2-phenylethyl]amino}-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2014-02-21 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
6OA0	Structure of human PARG complexed with JA2-9 分子名称: 4-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)butanoic acid, Poly(ADP-ribose) glycohydrolase 著者 Stegeman, R.A, Jones, D.E, Ellenberger, T, Kim, I.K, Tainer, J.A. 登録日 2019-03-15 公開日 2019-12-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nat Commun, 10, 2019
4OTT	Crystal structure of the gamma-glutamyltranspeptidase from Bacillus licheniformis. 分子名称: Gamma glutamyl transpeptidase, Gamma-glutamyltranspeptidase, MAGNESIUM ION 著者 Merlino, A. 登録日 2014-02-14 公開日 2014-07-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Low resolution X-ray structure of gamma-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion. Biochim.Biophys.Acta, 1844, 2014
4OVG	E. coli sliding clamp in complex with (R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid 分子名称: (2R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2014-02-21 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
4OX2	I45T cytosolic phosphoenolpyruvate carboxykinase in complex with beta-sulfopyruvate and GTP 分子名称: 2-ETHOXYETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Holyoak, T. 登録日 2014-02-04 公開日 2014-06-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity. Mol.Genet.Metab., 113, 2014
6OMW	Structure of Aedes aegypti OBP22 in the complex with palmitoleic acid 分子名称: AAEL005772-PA, MALONIC ACID, PALMITOLEIC ACID 著者 Jones, D.N, Wang, J. 登録日 2019-04-19 公開日 2019-05-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. Sci Rep, 10, 2020
6PT6	Crystal structure of PsS1_NC C84S in complex with i-neocarratetraose 分子名称: 3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, exo-2S-iota carrageenan S1 sulfatase 著者 Hettle, A.G, Boraston, A.B. 登録日 2019-07-15 公開日 2019-09-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
4RR6	N-terminal editing domain of threonyl-tRNA synthetase from Aeropyrum pernix with L-Ser3AA (snapshot 1) 分子名称: Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE 著者 Ahmad, S, Muthukumar, S, Yerabham, A.S.K, Kamarthapu, V, Sankaranarayanan, R. 登録日 2014-11-06 公開日 2015-07-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme. Nat Commun, 6, 2015

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