PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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5CWE	Structure of CYP107L2 from Streptomyces avermitilis with lauric acid 分子名称: Cytochrome P450 hydroxylase, GLYCEROL, LAURIC ACID, ... 著者 Pham, T.-V, Han, S.-H, Kim, J.-H, Kim, D.-H, Kang, L.-W. 登録日 2015-07-28 公開日 2016-08-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structure of CYP107L2 from Streptomyces avermitilis with lauric acid To Be Published
5HIW	Sorangium cellulosum So Ce56 cytochrome P450 260B1 分子名称: Cytochrome P450 CYP260B1, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Salamanca-Pinzon, S.G, Carius, Y, Khatri, Y, Bernhardt, R, Lancaster, C.R.D. 登録日 2016-01-12 公開日 2016-08-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-function analysis for the hydroxylation of Delta 4 C21-steroids by the myxobacterial CYP260B1. Febs Lett., 590, 2016
5A5J	Cytochrome 2C9 P450 inhibitor complex 分子名称: CYTOCHROME P450 2C9, N-[4-(3-chloranyl-4-cyano-phenoxy)-3,5-dimethoxy-phenyl]-1,1,1-tris(fluoranyl)methanesulfonamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Skerratt, S.E, de Groot, M.J, Phillips, C. 登録日 2015-06-18 公開日 2016-08-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery of a Novel Binding Pocket for Cyp 2C9 Inhibitors: Crystallography, Pharmacophore Modelling and Inhibitor Sar. To be Published
5EX6	Structure of P450 StaH from glycopeptide antibiotic A47934 biosynthesis 分子名称: 1,2-ETHANEDIOL, Cytochrome P450, GLYCEROL, ... 著者 Cryle, M.J, Ulrich, V. 登録日 2015-11-23 公開日 2016-08-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH. Mol Biosyst, 12, 2016
5A5I	Cytochrome 2C9 P450 inhibitor complex 分子名称: CYTOCHROME P450 2C9, N-[4-(3-chloranyl-4-cyano-phenoxy)cyclohexyl]-1,1,1-tris(fluoranyl)methanesulfonamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Skerratt, S.E, de Groot, M.J, Phillips, C. 登録日 2015-06-18 公開日 2016-08-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of a Novel Binding Pocket for Cyp 2C9 Inhibitors: Crystallography, Pharmacophore Modelling and Inhibitor Sar. Med.Chem.Comm., 7, 2016
5L1P	X-ray Structure of Cytochrome P450 PntM with Pentalenolactone 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L1O	X-ray Structure of Cytochrome P450 PntM with Pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L1Q	X-ray Structure of Cytochrome P450 PntM with Dihydropentalenolactone F 分子名称: Dihydropentalenolactone F, PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L1S	X-ray Structure of F232L mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L1W	X-ray Structure of 2-Mercaptoethanol modified M81C mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L1V	X-ray Structure of M81C mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L1R	X-ray Structure of the Substrate-free Cytochrome P450 PntM 分子名称: BICINE, PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L1U	X-ray Structure of M81A mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.074 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L1T	X-ray Structure of M77S mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.082 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5E78	Crystal structure of P450 BM3 heme domain variant complexed with Co(III)Sep 分子名称: 1,3,6,8,10,13,16,19-octaazabicyclo[6.6.6]icosane, Bifunctional P-450/NADPH-P450 reductase, CHLORIDE ION, ... 著者 Panneerselvm, S, Shehzad, A, Bocola, M, Mueller-Dieckmann, J, Schwaneberg, U. 登録日 2015-10-12 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic insights into a cobalt (III) sepulchrate based alternative cofactor system of P450 BM3 monooxygenase. Biochim. Biophys. Acta, 1866, 2018
5JQV	Crystal structure of Cytochrome P450 BM3 heme domain T269V/L272W/L322I/A406S (WIVS) variant with iron(III) deuteroporphyrin IX bound 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, FE(III) DEUTEROPORPHYRIN IX 著者 Reynolds, E.W, McHenry, M.W, Cannac, F, Gober, J.G, Snow, C.D, Brustad, E.M. 登録日 2016-05-05 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 An Evolved Orthogonal Enzyme/Cofactor Pair. J.Am.Chem.Soc., 138, 2016
5JQU	Crystal structure of Cytochrome P450 BM3 heme domain G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) variant with iron(III) deuteroporphyrin IX bound 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, FE(III) DEUTEROPORPHYRIN IX 著者 Reynolds, E.W, McHenry, M.W, Cannac, F, Gober, J.G, Snow, C.D, Brustad, E.M. 登録日 2016-05-05 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.162 Å) 主引用文献 An Evolved Orthogonal Enzyme/Cofactor Pair. J.Am.Chem.Soc., 138, 2016
5L94	The 2.25 A crystal structure of CYP109E1 from Bacillus megaterium in complex with testosterone 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
5L92	The 2.1 A crystal structure of CYP109E1 from Bacillus megaterium in complex with corticosterone 分子名称: CORTICOSTERONE, Cytochrome P450, MALONIC ACID, ... 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
5L91	The 2.2 A crystal structure of CYP109E1 from Bacillus megaterium bound with four corticosterone molecules 分子名称: CORTICOSTERONE, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
5L90	The crystal structure of substrate-free CYP109E1 from Bacillus megaterium at 2.55 Angstrom resolution 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
5JQ2	Crystal structure of the Ru(bpy)2PhenA functionalized P450 BM3 L407C heme domain mutant in complex with N-palmitoylglycine 分子名称: N-PALMITOYLGLYCINE, P450 BM3 L407C heme domain mutant, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Kloos, M. 登録日 2016-05-04 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insights into an efficient light-driven hybrid P450 BM3 enzyme from crystallographic, spectroscopic and biochemical studies. Biochim.Biophys.Acta, 1864, 2016
5JTD	Crystal structure of the Ru(bpy)2PhenA functionalized P450 BM3 L407C heme domain mutant in complex with DMSO. 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Kloos, M. 登録日 2016-05-09 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Insights into an efficient light-driven hybrid P450 BM3 enzyme from crystallographic, spectroscopic and biochemical studies. Biochim.Biophys.Acta, 1864, 2016
5ESE	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73R mutant complexed with fluconazole 分子名称: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. 登録日 2015-11-16 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase. Antimicrob.Agents Chemother., 62, 2018
5ESF	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73E mutant complexed with fluconazole 分子名称: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. 登録日 2015-11-16 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase. Antimicrob.Agents Chemother., 62, 2018

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