5A5J
Cytochrome 2C9 P450 inhibitor complex
Summary for 5A5J
| Entry DOI | 10.2210/pdb5a5j/pdb |
| Related | 5A5I |
| Descriptor | CYTOCHROME P450 2C9, PROTOPORPHYRIN IX CONTAINING FE, N-[4-(3-chloranyl-4-cyano-phenoxy)-3,5-dimethoxy-phenyl]-1,1,1-tris(fluoranyl)methanesulfonamide (3 entities in total) |
| Functional Keywords | oxidoreductase |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P11712 |
| Total number of polymer chains | 1 |
| Total formula weight | 55376.16 |
| Authors | |
| Primary citation | Skerratt, S.E.,De Groot, M.J.,Phillips, C. Discovery of a Novel Binding Pocket for Cyp 2C9 Inhibitors: Crystallography, Pharmacophore Modelling and Inhibitor Sar. To be Published, |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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