6J4Y
 
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1B) | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
|
|
6PWV
 | | Cryo-EM structure of MLL1 core complex bound to the nucleosome | | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | | 登録日 | 2019-07-23 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
|
|
3G5I
 | | Crystal Structure of the E.coli RihA pyrimidine nucleosidase bound to a iminoribitol-based inhibitor | | 分子名称: | (2S,3S,4R,5R)-2-(3,4-diaminophenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol, BETA-MERCAPTOETHANOL, CALCIUM ION, ... | | 著者 | Garau, G, Muzzolini, L, Tornaghi, P, Degano, M. | | 登録日 | 2009-02-05 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor.
Bmc Struct.Biol., 10, 2010
|
|
6LTJ
 | | Structure of nucleosome-bound human BAF complex | | 分子名称: | AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... | | 著者 | He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. | | 登録日 | 2020-01-22 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of nucleosome-bound human BAF complex.
Science, 367, 2020
|
|
6J4Z
 | | RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome | | 分子名称: | DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... | | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
|
|
6J51
 | | RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome, weak Elf1 (+1 position) | | 分子名称: | DNA (198-MER), DNA (36-MER), DNA-directed RNA polymerase subunit, ... | | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
|
|
6J4X
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1A) | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
|
|
6UXW
 | | SWI/SNF nucleosome complex with ADP-BeFx | | 分子名称: | 601 sequence bottom strand, 601 sequence top strand, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | He, Y, Han, Y. | | 登録日 | 2019-11-08 | | 公開日 | 2020-03-18 | | 最終更新日 | 2025-05-21 | | 実験手法 | ELECTRON MICROSCOPY (8.96 Å) | | 主引用文献 | Cryo-EM structure of SWI/SNF complex bound to a nucleosome.
Nature, 579, 2020
|
|
6K1K
 | | Human nucleosome core particle with H2A.X S139E variant | | 分子名称: | CHLORIDE ION, DNA (145-MER), Histone H2AX, ... | | 著者 | Sharma, D, De Falco, L, Davey, C.A. | | 登録日 | 2019-05-10 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
|
|
6K1J
 | | Human nucleosome core particle with H2A.X variant | | 分子名称: | CHLORIDE ION, DNA (145-MER), Histone H2AX, ... | | 著者 | Sharma, D, De Falco, L, Davey, C.A. | | 登録日 | 2019-05-10 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
|
|
3QO9
 | | Crystal structure of HIV-1 Reverse Transcriptase (RT) in complex with TSAO-T, a non-nucleoside RT inhibitor (NNRTI) | | 分子名称: | 1-[(5R,6R,8R,9R)-4-amino-9-{[tert-butyl(dimethyl)silyl]oxy}-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2,2-dioxido-1,7-dioxa-2-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4(1H,3H)-dione, Reverse transcriptase/ ribonuclease H, p51 RT | | 著者 | Das, K, Arnold, E. | | 登録日 | 2011-02-09 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of tert-Butyldimethylsilyl-spiroaminooxathioledioxide-thymine (TSAO-T) in Complex with HIV-1 Reverse Transcriptase (RT) Redefines the Elastic Limits of the Non-nucleoside Inhibitor-Binding Pocket.
J.Med.Chem., 54, 2011
|
|
6T78
 | | Structure of human Sox11 transcription factor in complex with a short DNA fragment | | 分子名称: | DNA (5'-D(*AP*AP*CP*AP*AP*AP*AP*TP*AP*AP*AP*CP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*GP*TP*TP*TP*AP*TP*TP*TP*TP*GP*TP*T)-3'), Transcription factor SOX-11 | | 著者 | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | | 登録日 | 2019-10-21 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.504 Å) | | 主引用文献 | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
|
|
9JAO
 | | The structure of SMARCAD1 bound to the hexasome in the presence of ADP-BeFx | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (157-MER), ... | | 著者 | Chen, Z.C, Hu, P.J, Sia, Y.Y, Chen, K.J, Xia, X. | | 登録日 | 2024-08-25 | | 公開日 | 2025-04-30 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Subnucleosome preference of human chromatin remodeller SMARCAD1.
Nature, 2025
|
|
6K1I
 | | Human nucleosome core particle with gammaH2A.X variant | | 分子名称: | CHLORIDE ION, DNA (147-MER), Histone H2AX, ... | | 著者 | Sharma, D, De Falco, L, Davey, C.A. | | 登録日 | 2019-05-10 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
|
|
6SEG
 | | Class1: CENP-A nucleosome in complex with CENP-C central region | | 分子名称: | DNA (145-MER), Histone H2A type 2-A, Histone H2B type 1-C/E/F/G/I, ... | | 著者 | Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. | | 登録日 | 2019-07-30 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
|
|
6SE0
 | | Class 1 : CENP-A nucleosome | | 分子名称: | DNA (145-MER), Histone H2A type 2-A, Histone H2B type 1-C/E/F/G/I, ... | | 著者 | Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. | | 登録日 | 2019-07-29 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
|
|
1WKK
 | |
6SEE
 | | Class2A : CENP-A nucleosome in complex with CENP-C central region | | 分子名称: | Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ... | | 著者 | Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. | | 登録日 | 2019-07-29 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
|
|
6JXD
 | |
6KW3
 | | The ClassA RSC-Nucleosome Complex | | 分子名称: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | | 著者 | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | 登録日 | 2019-09-05 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (7.13 Å) | | 主引用文献 | Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
|
|
8OFF
 | | Structure of BARD1 ARD-BRCTs in complex with H2AKc15ub nucleosomes (Map1) | | 分子名称: | BRCA1 associated RING domain 1, DNA (142-MER), Histone H2A type 1, ... | | 著者 | Foglizzo, M, Burdett, H, Wilson, M.D, Zeqiraj, E. | | 登録日 | 2023-03-15 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes.
Nucleic Acids Res., 51, 2023
|
|
6SEF
 | | Class2C : CENP-A nucleosome in complex with CENP-C central region | | 分子名称: | Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ... | | 著者 | Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. | | 登録日 | 2019-07-29 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
|
|
6KW4
 | | The ClassB RSC-Nucleosome Complex | | 分子名称: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | | 著者 | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | 登録日 | 2019-09-06 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (7.55 Å) | | 主引用文献 | Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
|
|
6SE6
 | | Class2 : CENP-A nucleosome in complex with CENP-C central region | | 分子名称: | Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ... | | 著者 | Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. | | 登録日 | 2019-07-29 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
|
|
1YOE
 | |
