6F4K
 
 | | Crystal structure of glutathione transferase Omega 3S from Trametes versicolor in complex with hexyl-glutathione | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Schwartz, M, Favier, F, Didierjean, C. | | 登録日 | 2017-11-29 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor.
Sci Rep, 8, 2018
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6F51
 | | Crystal structure of glutathione transferase Omega 3S from Trametes versicolor in complex with glutathionyl-phenylacetophenone | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, L-gamma-glutamyl-S-(2-biphenyl-4-yl-2-oxoethyl)-L-cysteinylglycine, ... | | 著者 | Schwartz, M, Favier, F, Didierjean, C. | | 登録日 | 2017-11-30 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor.
Sci Rep, 8, 2018
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6X5Z
 | | Bovine Cardiac Myosin in Complex with Chicken Skeletal Actin and Human Cardiac Tropomyosin in the Rigor State | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Doran, M.H, Lehman, W, Rynkiewicz, M.J, Bullitt, E. | | 登録日 | 2020-05-27 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | | 主引用文献 | Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments.
Biophys.J., 119, 2020
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7AEN
 | | Galectin-8 N-terminal carbohydrate recognition domain in complex with methyl 3-O-((7-carboxy)quinolin-2-yl)-methoxy)-beta-D-galactopyranoside | | 分子名称: | CHLORIDE ION, GLYCEROL, Isoform 2 of Galectin-8, ... | | 著者 | Hassan, M, Klavern, V.S, Hakansson, M, Anderluh, M, Tomasic, T, Jakopin, Z, Nilsson, J.U, Kovacic, R, Walse, B, Diehl, C. | | 登録日 | 2020-09-17 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain
Acs Med.Chem.Lett., 12, 2021
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1BW7
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4P44
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5MEL
 | | Structure of an E333Q variant of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with Glc-alpha-1,3-(3R,4R,5R)-5-(hydroxymethyl)cyclohex-1,2-ene-3,4-diol | | 分子名称: | (1~{R},2~{R},6~{R})-6-(hydroxymethyl)cyclohex-3-ene-1,2-diol, ACETATE ION, Glycosyl hydrolase family 71, ... | | 著者 | Petricevic, M, Sobala, L.F, Fernandes, P.Z, Raich, L, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J. | | 登録日 | 2016-11-15 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-alpha-1,2-Mannanase.
J. Am. Chem. Soc., 139, 2017
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6YAJ
 | | Split gene transketolase, inactive beta4 tetramer | | 分子名称: | 1,2-ETHANEDIOL, C-terminal chain of split transketolase from Carboxydothermus hydrogenoformans, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Isupov, M.N, Littlechild, J.A, James, P. | | 登録日 | 2020-03-12 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A 'Split-Gene' Transketolase From the Hyper-Thermophilic Bacterium Carboxydothermus hydrogenoformans : Structure and Biochemical Characterization.
Front Microbiol, 11, 2020
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6FAM
 | | Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with mannose-alpha-1,3-2-aminodeoxymannojirimycin | | 分子名称: | ACETATE ION, Glycosyl hydrolase family 71, alpha-D-mannopyranose, ... | | 著者 | Fernandes, P.Z, Petricevic, M, Sobala, L.F, Davies, G.J, Williams, S.J. | | 登録日 | 2017-12-15 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Exploration of Strategies for Mechanism-Based Inhibitor Design for Family GH99 endo-alpha-1,2-Mannanases.
Chemistry, 24, 2018
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1KE6
 | | CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE | | 分子名称: | Cell division protein kinase 2, N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE | | 著者 | Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.H, Shewchuk, L.M, Kuyper, L.F. | | 登録日 | 2001-11-14 | | 公開日 | 2002-05-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis.
J.Med.Chem., 44, 2001
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6FCM
 | | Crystal structure of human PCNA | | 分子名称: | Proliferating cell nuclear antigen | | 著者 | Housset, D, Frachet, P. | | 登録日 | 2017-12-20 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
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1KDW
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5MHH
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6YMU
 | | Imidazole Glycerol Phosphate Synthase | | 分子名称: | Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH | | 著者 | Sterner, R, Rajendran, C, Andrea, K. | | 登録日 | 2020-04-09 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Significance of the Protein Interface Configuration for Allostery in Imidazole Glycerol Phosphate Synthase.
Biochemistry, 59, 2020
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8PV2
 | | Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1 | | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | 登録日 | 2023-07-17 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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7B0M
 | | Sugar transaminase from a metagenome collected from troll oil field production water | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Sugar aminotransferase, ... | | 著者 | Littlechild, J.A, De Rose, S.A, Isupov, M.N, Sayer, C, Karki, S. | | 登録日 | 2020-11-20 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Sugar transaminases from hot environments
To Be Published
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8PUW
 | | Chaetomium thermophilum Las1-Grc3-complex | | 分子名称: | Las1, Polynucleotide 5'-hydroxyl-kinase GRC3 | | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | 登録日 | 2023-07-17 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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7B0D
 | | Sugar transaminase from Archaeoglobus veneficus | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | James, P, Littlechild, J.A, De Rose, S.A, Isupov, M.N. | | 登録日 | 2020-11-19 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Sugar transaminases from hot environments
To Be Published
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8PV3
 | | Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite structure | | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | 登録日 | 2023-07-17 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PV7
 | | Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite structure | | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | 登録日 | 2023-07-17 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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6MYA
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8PTW
 | | Chaetomium thermophilum Rix1-complex | | 分子名称: | Pre-rRNA-processing protein IPI3, Pre-rRNA-processing protein RIX1 | | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | 登録日 | 2023-07-15 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8R4Q
 | | Salt inducible kinase 3 in complex with inhibitor | | 分子名称: | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, SULFATE ION, Serine/threonine-protein kinase SIK3, ... | | 著者 | Kack, H, Oster, L. | | 登録日 | 2023-11-14 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.838 Å) | | 主引用文献 | The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
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8R4V
 | | Structure of Salt-inducible kinase 3 in complex with inhibitor | | 分子名称: | 1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]urea, Serine/threonine-protein kinase SIK3 | | 著者 | Kack, H, Oster, L. | | 登録日 | 2023-11-14 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
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8R4O
 | | Salt inducible kinase 3 in complex with inhibitor | | 分子名称: | 2-[bis(fluoranyl)methoxy]-4-[6-(2-cyanopropan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]-~{N}-[(1~{R},2~{S})-2-fluoranylcyclopropyl]-6-methoxy-benzamide, SULFATE ION, Serine/threonine-protein kinase SIK3, ... | | 著者 | Kack, H, Oster, L. | | 登録日 | 2023-11-14 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.725 Å) | | 主引用文献 | The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
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