1KDW
X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 4-carboxyphenylboronic acid
Summary for 1KDW
| Entry DOI | 10.2210/pdb1kdw/pdb |
| Related | 1C3B 1GA9 1KDS 1KE0 1KE3 1KE4 3BLS |
| Descriptor | beta-lactamase, PHOSPHATE ION, 4-CARBOXYPHENYLBORONIC ACID, ... (4 entities in total) |
| Functional Keywords | cephalosporinase, beta-lactamase, serine hydrolase, phenylboronic acid inhibitor, hydrolase |
| Biological source | Escherichia coli |
| Cellular location | Periplasm: P00811 |
| Total number of polymer chains | 2 |
| Total formula weight | 79602.69 |
| Authors | Powers, R.A.,Shoichet, B.K. (deposition date: 2001-11-13, release date: 2002-07-17, Last modification date: 2023-08-16) |
| Primary citation | Powers, R.A.,Shoichet, B.K. Structure-based approach for binding site identification on AmpC beta-lactamase. J.Med.Chem., 45:3222-3234, 2002 Cited by PubMed: 12109906DOI: 10.1021/jm020002p PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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