PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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2HH0	Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope. 分子名称: Heavy Chain, P-Clone Fab, Chimera, ... 著者 Kanyo, Z.K. 登録日 2006-06-27 公開日 2006-12-26 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation J.Mol.Biol., 363, 2006
5JQ7	Crystal structure of Ebola glycoprotein in complex with toremifene 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Envelope glycoprotein 1,Envelope glycoprotein 1,Envelope glycoprotein 1, ... 著者 Zhao, Y, Ren, J, Stuart, D.I. 登録日 2016-05-04 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature, 535, 2016
7AJ6	LN02 Fab 分子名称: LN02, LN02 heavy chain 著者 Caillat, C, Fenwick, G, Pantaleo, G, Weissenhorn, W. 登録日 2020-09-28 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 LN02 Fab To Be Published
5KAR	Murine acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3b, ... 著者 Gorelik, A, Illes, K, Heinz, L.X, Superti-Furga, G, Nagar, B. 登録日 2016-06-02 公開日 2016-10-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.142 Å) 主引用文献 Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. J.Biol.Chem., 291, 2016
5KTZ	expanded poliovirus in complex with VHH 12B 分子名称: Genome polyprotein, VHH 12B, VP1, ... 著者 Strauss, M, Schotte, L, Filman, D.J, Hogle, J.M. 登録日 2016-07-12 公開日 2016-11-02 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State. J. Virol., 91, 2017
3SQO	PCSK9 J16 Fab complex 分子名称: J16 Heavy chain, J16 Light chain, PCSK9 prodomain, ... 著者 Strop, P. 登録日 2011-07-05 公開日 2012-05-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates. J.Pharmacol.Exp.Ther., 340, 2012
5N2D	Structure of PD-L1/small-molecule inhibitor complex 分子名称: Programmed cell death 1 ligand 1, ~{N}-[2-[[2,6-dimethoxy-4-[(2-methyl-3-phenyl-phenyl)methoxy]phenyl]methylamino]ethyl]ethanamide 著者 Guzik, K, Zak, K.M, Grudnik, P, Dubin, G, Holak, T.A. 登録日 2017-02-07 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1. J. Med. Chem., 60, 2017
7Q1Z	Structure of formaldehyde cross-linked SARS-CoV-2 S glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Sulbaran, G, Effantin, G, Schoehn, G, Weissenhorn, W. 登録日 2021-10-22 公開日 2022-03-09 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Immunization with synthetic SARS-CoV-2 S glycoprotein virus-like particles protects macaques from infection. Cell Rep Med, 3, 2022
7PGF	Calcium-selective Sp1 channel pore domain only 分子名称: Ion transporter 著者 Lolicato, M, Arrigoni, C. 登録日 2021-08-13 公開日 2022-06-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
7PGG	NaVAb1p detergent (DM) 分子名称: 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein 著者 Lolicato, M, Arrigoni, C. 登録日 2021-08-13 公開日 2022-06-15 最終更新日 2022-06-29 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
4ERS	A Molecular Basis for Negative Regulation of the Glucagon Receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... 著者 Murray, J.M, Koth, C.M, Mukund, S. 登録日 2012-04-20 公開日 2012-08-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.637 Å) 主引用文献 Molecular basis for negative regulation of the glucagon receptor. Proc.Natl.Acad.Sci.USA, 109, 2012
5N2F	Structure of PD-L1/small-molecule inhibitor complex 分子名称: 4-[[4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-phenyl]methoxy]-2,5-bis(fluoranyl)phenyl]methylamino]-3-oxidanylidene-butanoic acid, Programmed cell death 1 ligand 1 著者 Guzik, K, Zak, K.M, Grudnik, P, Dubin, G, Holak, T.A. 登録日 2017-02-07 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1. J. Med. Chem., 60, 2017
6VRP	Reverse Transcriptase Diabody with R83T Mutation 分子名称: 1,2-ETHANEDIOL, SULFATE ION, Single-chain Fv 著者 Chesterman, C, Arnold, E. 登録日 2020-02-08 公開日 2021-02-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Co-crystallization with diabodies: A case study for the introduction of synthetic symmetry. Structure, 29, 2021
6VUG	Diabody bound to a Reverse Transcriptase Aptamer Complex 分子名称: DNA (38-MER), GLYCEROL, Heavy chain variable fragment, ... 著者 Chesterman, C, Arnold, E. 登録日 2020-02-15 公開日 2021-02-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Co-crystallization with diabodies: A case study for the introduction of synthetic symmetry. Structure, 29, 2021
6P3S	Crystal structure of human Fab H5.28 in complex with influenza A H5N1 Vietnam hemagglutinin head domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Human Fab H5.28 heavy chain, ... 著者 Dong, J, Crowe, J.E. 登録日 2019-05-24 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 crystal structure of human Fab H5.28 in complex with influenza A H5N1 Vietnam hemagglutinin head domain To Be Published
6P3R	crystal structure of human Fab H5.31 in complex with influenza A H5N1 Vietnam hemagglutinin head domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Dong, J, Crowe, J.E. 登録日 2019-05-24 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of human Fab H5.31 in complex with influenza A H5N1 Vietnam hemagglutinin head domain To Be Published
7SSC	TRL345 lineage ancestor I8 Fab bound to an HCMV gB-derived peptide 分子名称: Envelope glycoprotein B peptide, GLYCEROL, TRL345-I8 Fab heavy chain, ... 著者 Sponholtz, M.R, McLellan, J.S. 登録日 2021-11-10 公開日 2022-10-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus. Plos Pathog., 19, 2023
3WYQ	Crystal structure of the low-immunogenic core streptavidin mutant LISA-314 (Y22S/Y83S/R84K/E101D/R103K/E116N) at 1.0 A resolution 分子名称: BIOTIN, GLYCEROL, SULFATE ION, ... 著者 Kawato, T, Mizohata, E, Meshizuka, T, Doi, H, Kawamura, T, Matsumura, H, Yumura, K, Tsumoto, K, Kodama, T, Inoue, T, Sugiyama, A. 登録日 2014-09-05 公開日 2014-12-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Crystal structure of streptavidin mutant with low immunogenicity. J.Biosci.Bioeng., 119, 2015
3WYP	Crystal structure of wild-type core streptavidin in complex with D-biotin/biotin-D-sulfoxide at 1.3 A resolution 分子名称: BIOTIN, BIOTIN-D-SULFOXIDE, GLYCEROL, ... 著者 Kawato, T, Mizohata, E, Meshizuka, T, Doi, H, Kawamura, T, Matsumura, H, Yumura, K, Tsumoto, K, Kodama, T, Inoue, T, Sugiyama, A. 登録日 2014-09-05 公開日 2014-12-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of streptavidin mutant with low immunogenicity. J.Biosci.Bioeng., 119, 2015
3X0F	Crystal structure of the ectodomain of mouse CD81 large extracellular loop (mCD81-LEL) 分子名称: CD81 antigen, ISOPROPYL ALCOHOL 著者 Zhang, M, Cui, S. 登録日 2014-10-14 公開日 2015-07-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.471 Å) 主引用文献 An intramolecular bond at cluster of differentiation 81 ectodomain is important for hepatitis C virus entry. Faseb J., 29, 2015
3X0E	Crystal structure of the ectodomain of human CD81 large extracellular loop (hCD81-LEL) 分子名称: CD81 antigen, MAGNESIUM ION 著者 Zhang, M, Cui, S. 登録日 2014-10-14 公開日 2015-07-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.844 Å) 主引用文献 An intramolecular bond at cluster of differentiation 81 ectodomain is important for hepatitis C virus entry. Faseb J., 29, 2015
3ZLQ	BACE2 XAPERONE COMPLEX 分子名称: 5-Ethoxy-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide, BETA-SECRETASE 2, XA4813 著者 Kuglstatter, A, Stihle, M. 登録日 2013-02-04 公開日 2013-05-01 最終更新日 2013-06-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Beta-Secretase (Bace1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer'S Disease. J.Med.Chem., 56, 2013
3ZHG	Crystallographic structure of the native mouse SIGN-R1 CRD domain 分子名称: CALCIUM ION, CD209 ANTIGEN-LIKE PROTEIN B, SULFATE ION 著者 Silva-Martin, N, Bartual, S.G, Hermoso, J.A. 登録日 2012-12-21 公開日 2014-01-15 最終更新日 2020-03-11 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor Sign-R1. Structure, 22, 2014
3ZQK	Von Willebrand Factor A2 domain with calcium 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... 著者 Jakobi, A.J, Huizinga, E.G. 登録日 2011-06-09 公開日 2011-07-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Calcium Modulates Force Sensing by the Von Willebrand Factor A2 Domain. Nat.Commun., 2, 2011
5VYH	Crystal Structure of MERS-CoV S1 N-terminal Domain 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ... 著者 Wang, N, Wrapp, D, Pallesen, J, Ward, A.B, McLellan, J.S. 登録日 2017-05-25 公開日 2017-08-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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