PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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6DIL	HIV-1 protease with single mutation L76V in complex with tipranavir 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Wong-Sam, A.E, Wang, Y.-F, Weber, I.T. 登録日 2018-05-23 公開日 2018-10-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.482 Å) 主引用文献 Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap-Core Interface of HIV-1 Protease. ACS Omega, 3, 2018
6B3H	Crystal Structure of HIV Protease complexed with N-(2-(2-((6R,9S)-2,2-dioxido-2-thia-1,7-diazabicyclo[4.3.1]decan-9-yl)ethyl)-3-fluorophenyl)-3,3-bis(4-fluorophenyl)propanamide 分子名称: CHLORIDE ION, HIV-1 Protease, N-(2-{2-[(6R,9S)-2,2-dioxo-2lambda~6~-thia-1,7-diazabicyclo[4.3.1]decan-9-yl]ethyl}-3-fluorophenyl)-3,3-bis(4-fluorophenyl)propanamide 著者 Su, H.P. 登録日 2017-09-21 公開日 2018-01-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors. ACS Med Chem Lett, 8, 2017
4OF9	Structure of K42N variant of sperm whale myoglobin 分子名称: 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Lebioda, L, Wang, C, Lovelace, L.L. 登録日 2014-01-14 公開日 2014-11-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.241 Å) 主引用文献 Structures of K42N and K42Y sperm whale myoglobins point to an inhibitory role of distal water in peroxidase activity. Acta Crystallogr.,Sect.D, 70, 2014
6DJ2	HIV-1 protease with single mutation L76V in complex with Lopinavir 分子名称: CHLORIDE ION, HIV-1 protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE, ... 著者 Wang, Y.-F, Wong-Sam, A.E, Zhang, Y, Weber, I.T. 登録日 2018-05-24 公開日 2018-10-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap-Core Interface of HIV-1 Protease. ACS Omega, 3, 2018
6DJN	Cryo-EM structure of ADP-Pi-actin filaments 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Chou, S.Z, Pollard, T.D. 登録日 2018-05-25 公開日 2019-02-27 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
6KAH	Crosslinked alpha(Ni)-beta(Fe-CO) human hemoglobin A in the T quaternary structure at 95 K: Dark 分子名称: BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin subunit alpha, ... 著者 Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A. 登録日 2019-06-23 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Direct observation of ligand migration within human hemoglobin at work. Proc.Natl.Acad.Sci.USA, 117, 2020
6KAQ	Carbonmonoxy human hemoglobin C in the R quaternary structure at 140 K: Dark 分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A. 登録日 2019-06-24 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Direct observation of ligand migration within human hemoglobin at work. Proc.Natl.Acad.Sci.USA, 117, 2020
7VV8	Crystal Structure of HRasQ61L(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Zheng, Y.Y, Zhou, C. 登録日 2021-11-04 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
6KAU	Carbonmonoxy human hemoglobin A in the R2 quaternary structure at 140 K: Dark 分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A. 登録日 2019-06-24 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Direct observation of ligand migration within human hemoglobin at work. Proc.Natl.Acad.Sci.USA, 117, 2020
7E99	Oxy-deoxy intermediate of 400 kDa giant hemoglobin at 13% oxygen saturation 分子名称: Extracellular giant hemoglobin major globin subunit A1, Extracellular giant hemoglobin major globin subunit A2, Extracellular giant hemoglobin major globin subunit B2, ... 著者 Numoto, N, Kawano, Y, Okumura, H, Baba, S, Fukumori, Y, Miki, K, Ito, N. 登録日 2021-03-03 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Coarse snapshots of oxygen-dissociation intermediates of a giant hemoglobin elucidated by determining the oxygen saturation in individual subunits in the crystalline state. Iucrj, 8, 2021
5X2U	Direct Observation of Conformational Population Shifts in Hemoglobin: Crystal Structure of Half-Liganded Hemoglobin after Adding 80 mM phosphate pH 6.7. 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Ohki, M, Park, S.-Y. 登録日 2017-02-02 公開日 2017-09-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Direct observation of conformational population shifts in crystalline human hemoglobin. J. Biol. Chem., 292, 2017
6B6S	Orthorhombic trypsin cryocooled to 100 K with 50% ethanol as cryoprotectant 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Juers, D.H. 登録日 2017-10-03 公開日 2017-11-01 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.0002284 Å) 主引用文献 The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
7VLD	Oxy-deoxy intermediate of V2 hemoglobin at 69% oxygen saturation 分子名称: CALCIUM ION, Extracellular A1 globin, Extracellular A2 globin, ... 著者 Numoto, N, Onoda, S, Kawano, Y, Okumura, H, Baba, S, Fukumori, Y, Miki, K, Ito, N. 登録日 2021-10-02 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of oxygen dissociation intermediates of 400 kDa V2 hemoglobin provide coarse snapshots of the protein allostery. Biophys Physicobio., 19, 2022
6D40	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma 分子名称: Plasminogen, SULFATE ION, Trypsin inhibitor 1 著者 Law, R.H.P, Wu, G. 登録日 2018-04-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
5X40	Structure of a CbiO dimer bound with AMPPCP 分子名称: Cobalt ABC transporter ATP-binding protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Bao, Z, Qi, X, Wang, J, Zhang, P. 登録日 2017-02-09 公開日 2017-04-05 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure and mechanism of a group-I cobalt energy coupling factor transporter Cell Res., 27, 2017
7VLF	Oxy-deoxy intermediate of V2 hemoglobin at 26% oxygen saturation 分子名称: CALCIUM ION, Extracellular A1 globin, Extracellular A2 globin, ... 著者 Numoto, N, Onoda, S, Kawano, Y, Okumura, H, Baba, S, Fukumori, Y, Miki, K, Ito, N. 登録日 2021-10-02 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of oxygen dissociation intermediates of 400 kDa V2 hemoglobin provide coarse snapshots of the protein allostery. Biophys Physicobio., 19, 2022
6B81	Crystal structure of Myotoxin II from Bothrops moojeni complexed to Caprylic acid 分子名称: Basic phospholipase A2 homolog 2, OCTANOIC ACID (CAPRYLIC ACID), SULFATE ION 著者 Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M. 登録日 2017-10-05 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin. Biochim Biophys Acta Proteins Proteom, 1866, 2018
7VLC	Oxy-deoxy intermediate of V2 hemoglobin at 78% oxygen saturation 分子名称: CALCIUM ION, Extracellular A1 globin, Extracellular A2 globin, ... 著者 Numoto, N, Onoda, S, Kawano, Y, Okumura, H, Baba, S, Fukumori, Y, Miki, K, Ito, N. 登録日 2021-10-02 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of oxygen dissociation intermediates of 400 kDa V2 hemoglobin provide coarse snapshots of the protein allostery. Biophys Physicobio., 19, 2022
7N1R	A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP 分子名称: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP, ... 著者 Yang, J, Musayev, F, Liu, Q. 登録日 2021-05-28 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP). Protein Sci., 31, 2022
7E97	Oxy-deoxy intermediate of 400 kDa giant hemoglobin at 58% oxygen saturation 分子名称: Extracellular giant hemoglobin major globin subunit A1, Extracellular giant hemoglobin major globin subunit A2, Extracellular giant hemoglobin major globin subunit B2, ... 著者 Numoto, N, Kawano, Y, Okumura, H, Baba, S, Fukumori, Y, Miki, K, Ito, N. 登録日 2021-03-03 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Coarse snapshots of oxygen-dissociation intermediates of a giant hemoglobin elucidated by determining the oxygen saturation in individual subunits in the crystalline state. Iucrj, 8, 2021
7E98	Oxy-deoxy intermediate of 400 kDa giant hemoglobin at 21% oxygen saturation 分子名称: Extracellular giant hemoglobin major globin subunit A1, Extracellular giant hemoglobin major globin subunit A2, Extracellular giant hemoglobin major globin subunit B2, ... 著者 Numoto, N, Kawano, Y, Okumura, H, Baba, S, Fukumori, Y, Miki, K, Ito, N. 登録日 2021-03-03 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Coarse snapshots of oxygen-dissociation intermediates of a giant hemoglobin elucidated by determining the oxygen saturation in individual subunits in the crystalline state. Iucrj, 8, 2021
6D3Y	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma 分子名称: GLYCEROL, Plasminogen, SULFATE ION, ... 著者 Law, R.H.P, Wu, G. 登録日 2018-04-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
7E96	Oxy-deoxy intermediate of 400 kDa giant hemoglobin at 69% oxygen saturation 分子名称: CALCIUM ION, Extracellular giant hemoglobin major globin subunit A1, Extracellular giant hemoglobin major globin subunit A2, ... 著者 Numoto, N, Kawano, Y, Okumura, H, Baba, S, Fukumori, Y, Miki, K, Ito, N. 登録日 2021-03-03 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Coarse snapshots of oxygen-dissociation intermediates of a giant hemoglobin elucidated by determining the oxygen saturation in individual subunits in the crystalline state. Iucrj, 8, 2021
4OOT	X-ray structure of the protein-gold adduct formed upon reaction of Aubipic with hen egg white lysozyme 分子名称: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ... 著者 Merlino, A. 登録日 2014-02-04 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Protein Recognition of Gold-Based Drugs: 3D Structure of the Complex Formed When Lysozyme Reacts with Aubipy(c.). ACS Med Chem Lett, 5, 2014
5X94	Crystal structure of SHP2_SH2-CagA EPIYA_D peptide complex 分子名称: Cag pathogenicity island protein, Tyrosine-protein phosphatase non-receptor type 11 著者 Senda, M, Senda, T. 登録日 2017-03-05 公開日 2017-09-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins. Cell Rep, 20, 2017

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