1G4H
 
 | LINB COMPLEXED WITH BUTAN-1-OL | 分子名称: | 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE, 1-BUTANOL, CALCIUM ION, ... | 著者 | Oakley, A.J, Prokop, Z, Bohac, M, Kmunicek, J, Jedlicka, T, Monincova, M, Kuta-Smatanova, I, Nagata, Y, Damborsky, J, Wilce, M.C.J. | 登録日 | 2000-10-27 | 公開日 | 2001-10-27 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition. Biochemistry, 41, 2002
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3N9K
 
 | F229A/E292S Double Mutant of Exo-beta-1,3-glucanase from Candida albicans in Complex with Laminaritriose at 1.7 A | 分子名称: | CALCIUM ION, Glucan 1,3-beta-glucosidase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, ... | 著者 | Nakatani, Y, Cutfield, S.M, Cutfield, J.F. | 登録日 | 2010-05-30 | 公開日 | 2010-09-15 | 最終更新日 | 2024-11-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Carbohydrate binding sites in Candida albicans exo-beta-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance Febs J., 277, 2010
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1GBG
 
 | BACILLUS LICHENIFORMIS BETA-GLUCANASE | 分子名称: | (1,3-1,4)-BETA-D-GLUCAN 4 GLUCANOHYDROLASE, CALCIUM ION | 著者 | Hahn, M, Heinemann, U. | 登録日 | 1995-08-25 | 公開日 | 1995-12-07 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Bacillus licheniformis 1,3-1,4-beta-D-glucan 4-glucanohydrolase at 1.8 A resolution. FEBS Lett., 374, 1995
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5Q03
 
 | Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(2-methylpropyl)thiophen-2-yl]sulfonylurea | 分子名称: | Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-(2-methylpropyl)thiophene-2-sulfonamide | 著者 | Ruf, A, Joseph, C, Alker, A, Banner, D, Tetaz, T, Benz, J, Kuhn, B, Rudolph, M.G, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-04-18 | 公開日 | 2019-01-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the
allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(2-methylpropyl)thiophen-2-yl]sulfonylurea To be published
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5Q01
 
 | Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(4,5-dichloro-2-methylpyrazol-3-yl)oxyphenyl]sulfonylurea | 分子名称: | Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-4-[(3,4-dichloro-1-methyl-1H-pyrazol-5-yl)oxy]benzene-1-sulfonamide | 著者 | Ruf, A, Joseph, C, Alker, A, Banner, D, Tetaz, T, Benz, J, Kuhn, B, Rudolph, M.G, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-04-18 | 公開日 | 2019-01-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | 主引用文献 | Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the
allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(4,5-dichloro-2-methylpyrazol-3-yl)oxyphenyl]sulfonylurea To be published
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2B4J
 
 | Structural basis for the recognition between HIV-1 integrase and LEDGF/p75 | 分子名称: | GLYCEROL, Integrase (IN), PC4 and SFRS1 interacting protein, ... | 著者 | Cherepanov, P, Ambrosio, A.L, Rahman, S, Ellenberger, T, Engelman, A. | 登録日 | 2005-09-24 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 Proc.Natl.Acad.Sci.Usa, 102, 2005
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3SKU
 
 | Herpes simplex virus glycoprotein D bound to the human receptor nectin-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein D, ... | 著者 | Di Giovine, P, Settembre, E.C, Bhargava, A.K, Luftig, M.A, Lou, H, Cohen, G.H, Eisenberg, R.J, Krummenacher, C, Carfi, A. | 登録日 | 2011-06-23 | 公開日 | 2011-10-12 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structure of herpes simplex virus glycoprotein d bound to the human receptor nectin-1. Plos Pathog., 7, 2011
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3H54
 
 | Crystal Structure of human alpha-N-acetylgalactosaminidase,complex with GalNAc | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Clark, N.E, Garman, S.C. | 登録日 | 2009-04-21 | 公開日 | 2009-10-20 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler and Kanzaki diseases J.Mol.Biol., 393, 2009
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3H53
 
 | Crystal Structure of human alpha-N-acetylgalactosaminidase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylgalactosaminidase, ... | 著者 | Clark, N.E, Garman, S.C. | 登録日 | 2009-04-21 | 公開日 | 2009-10-20 | 最終更新日 | 2024-11-27 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler and Kanzaki diseases J.Mol.Biol., 393, 2009
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2B4C
 
 | Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, T-cell surface glycoprotein CD4, ... | 著者 | Huang, C, Tang, M, Zhang, M.Y, Majeed, S, Montabana, E, Stanfield, R.L, Dimitrov, D.S, Korber, B, Sodroski, J, Wilson, I.A, Wyatt, R, Kwong, P.D. | 登録日 | 2005-09-23 | 公開日 | 2005-11-15 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of a V3-containing HIV-1 gp120 core. Science, 310, 2005
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2ASH
 
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2OD5
 
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1ZDT
 
 | The Crystal Structure of Human Steroidogenic Factor-1 | 分子名称: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Nuclear receptor coactivator 2, Steroidogenic factor 1 | 著者 | Wang, W, Zhang, C, Marimuthu, A, Krupka, H.I, Tabrizizad, M, Shelloe, R, Mehra, U, Eng, K, Nguyen, H, Settachatgul, C, Powell, B, Milburn, M.V, West, B.L. | 登録日 | 2005-04-14 | 公開日 | 2005-05-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1 Proc.Natl.Acad.Sci.USA, 102, 2005
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4JY4
 
 | Crystal structure of human Fab PGT121, a broadly reactive and potent HIV-1 neutralizing antibody | 分子名称: | GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PGT121 heavy chain, ... | 著者 | Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A. | 登録日 | 2013-03-29 | 公開日 | 2013-05-15 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Plos Pathog., 9, 2013
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2OJ9
 
 | Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor | 分子名称: | 3-[5-(1H-IMIDAZOL-1-YL)-7-METHYL-1H-BENZIMIDAZOL-2-YL]-4-[(PYRIDIN-2-YLMETHYL)AMINO]PYRIDIN-2(1H)-ONE, Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) | 著者 | Sack, J.S, Jacobson, B.L. | 登録日 | 2007-01-12 | 公開日 | 2007-05-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R). Bioorg.Med.Chem.Lett., 17, 2007
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7K54
 
 | Mid-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure II-FS) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | 登録日 | 2020-09-16 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun, 12, 2021
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2GVY
 
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7K53
 
 | Pre-translocation +1-frameshifting(CCC-A) complex (Structure I-FS) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | 登録日 | 2020-09-16 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun, 12, 2021
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7K55
 
 | Near post-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure III-FS) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | 登録日 | 2020-09-16 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun, 12, 2021
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2CMR
 
 | Crystal structure of the HIV-1 neutralizing antibody D5 Fab bound to the gp41 inner-core mimetic 5-helix | 分子名称: | D5, GLYCEROL, TRANSMEMBRANE GLYCOPROTEIN | 著者 | Luftig, M.A, Mattu, M, Di Giovine, P, Geleziunas, R, Hrin, R, Barbato, G, Bianchi, E, Miller, M.D, Pessi, A, Carfi, A. | 登録日 | 2006-05-11 | 公開日 | 2006-10-16 | 最終更新日 | 2024-11-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for HIV-1 Neutralization by a Gp41 Fusion Intermediate-Directed Antibody Nat.Struct.Mol.Biol., 13, 2006
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1U0A
 
 | Crystal structure of the engineered beta-1,3-1,4-endoglucanase H(A16-M) in complex with beta-glucan tetrasaccharide | 分子名称: | Beta-glucanase, CALCIUM ION, ZINC ION, ... | 著者 | Gaiser, O.J, Piotukh, K, Ponnuswamy, M.N, Planas, A, Borriss, R, Heinemann, U. | 登録日 | 2004-07-13 | 公開日 | 2005-09-06 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structural Basis for the Substrate Specificity of a Bacillus 1,3-1,4-beta-Glucanase J.Mol.Biol., 357, 2006
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2E9O
 
 | Structure of h-CHK1 complexed with AA582939 | 分子名称: | 4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID, Serine/threonine-protein kinase Chk1 | 著者 | Park, C. | 登録日 | 2007-01-26 | 公開日 | 2008-01-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors. Bioorg.Med.Chem., 15, 2007
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3OHF
 
 | Crystal structure of beta-site app-cleaving enzyme 1 (BACE-WT) complex with bms-655295 aka n~3~-((1s,2r)-1- benzyl-2-hydroxy-3-((3-methoxybenzyl)amino)propyl)-n~1~, n~1~-dibutyl-1h-indole-1,3-dicarboxamide | 分子名称: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | 著者 | Muckelbauer, J.K. | 登録日 | 2010-08-17 | 公開日 | 2011-04-06 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1. Bioorg.Med.Chem.Lett., 21, 2011
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3UR8
 
 | Lower-density crystal structure of potato endo-1,3-beta-glucanase | 分子名称: | Glucan endo-1,3-beta-D-glucosidase | 著者 | Wojtkowiak, A, Witek, K, Hennig, J, Jaskolski, M. | 登録日 | 2011-11-21 | 公開日 | 2012-05-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Two high-resolution structures of potato endo-1,3-beta-glucanase reveal subdomain flexibility with implications for substrate binding Acta Crystallogr.,Sect.D, 68, 2012
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2ONF
 
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