1I07
 
 | | EPS8 SH3 DOMAIN INTERTWINED DIMER | | 分子名称: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | | 著者 | Kishan, K.V.R, Newcomer, M.E. | | 登録日 | 2001-01-29 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
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1I0C
 | | EPS8 SH3 CLOSED MONOMER | | 分子名称: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | | 著者 | Kishan, K.V.R, Newcomer, M.E. | | 登録日 | 2001-01-29 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
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1IJE
 | | Nucleotide Exchange Intermediates in the eEF1A-eEF1Ba Complex | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, elongation factor 1-alpha, elongation factor 1-beta | | 著者 | Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J. | | 登録日 | 2001-04-26 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
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1IJF
 | | Nucleotide exchange mechanisms in the eEF1A-eEF1Ba complex | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, elongation factor 1-alpha, ... | | 著者 | Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J. | | 登録日 | 2001-04-26 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
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4DTD
 | | Structure and functional characterization of a Vibrio cholerae toxin from the MARTX/VgrG family. | | 分子名称: | GLYCEROL, VgrG protein | | 著者 | Durand, E, Audoly, G, Derrez, E, Spinelli, S, Ortiz-Lombardia, M, Cascales, E, Raoult, D, Cambillau, C. | | 登録日 | 2012-02-21 | | 公開日 | 2012-08-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and functional characterization of a Vibrio cholerae toxin
from the MARTX/VgrG family.
J.Biol.Chem., 2012
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1K58
 | | Crystal Structure of Human Angiogenin Variant D116H | | 分子名称: | Angiogenin | | 著者 | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | 登録日 | 2001-10-10 | | 公開日 | 2002-03-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1K59
 | | Crystal Structure of Human Angiogenin Variant Q117G | | 分子名称: | CITRIC ACID, angiogenin | | 著者 | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | 登録日 | 2001-10-10 | | 公開日 | 2002-03-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1K5B
 | | Crystal Structure of Human Angiogenin Variant des(121-123) | | 分子名称: | Angiogenin, CITRIC ACID | | 著者 | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | 登録日 | 2001-10-10 | | 公開日 | 2002-03-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1K5A
 | | Crystal structure of human angiogenin double variant I119A/F120A | | 分子名称: | Angiogenin | | 著者 | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | 登録日 | 2001-10-10 | | 公開日 | 2002-03-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1KMQ
 | | Crystal Structure of a Constitutively Activated RhoA Mutant (Q63L) | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Longenecker, K, Read, P, Lin, S.-K, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S. | | 登録日 | 2001-12-17 | | 公開日 | 2003-05-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
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4DTH
 | | Structure of a VgrG Vibrio cholerae toxin ACD domain in complex with ATP and Mg++ | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Durand, E, Audoly, G, Derrez, E, Spinelli, S, Ortiz-Lombardia, M, Cascales, E, Raoult, D, Cambillau, C. | | 登録日 | 2012-02-21 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure of a VgrG Vibrio cholerae toxin ACD domain in complex with ATP and Mg++
J.Biol.Chem., 2012
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1LB1
 | | Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA | | 分子名称: | Guanine nucleotide exchange factor DBS, Transforming protein RhoA | | 著者 | Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J. | | 登録日 | 2002-04-01 | | 公開日 | 2002-05-29 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
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3L50
 | | The crystal structure of human Glia Maturation Factor, Gamma (GMFG) | | 分子名称: | CHLORIDE ION, Glia maturation factor gamma | | 著者 | Ugochukwu, E, Pilka, E, Krysztofinska, E, Hapka, E, Krojer, T, Muniz, J, Vollmar, M, Pike, A.C.W, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K.L, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2009-12-21 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of human Glia Maturation Factor, Gamma (GMFG)
To be Published
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1LKJ
 | | NMR Structure of Apo Calmodulin from Yeast Saccharomyces cerevisiae | | 分子名称: | Calmodulin | | 著者 | Ishida, H, Nakashima, K, Kumaki, Y, Nakata, M, Hikichi, K, Yazawa, M. | | 登録日 | 2002-04-25 | | 公開日 | 2003-04-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of apocalmodulin from Saccharomyces cerevisiae implies a mechanism for its unique Ca2+ binding property.
Biochemistry, 41, 2002
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1J2J
 | | Crystal structure of GGA1 GAT N-terminal region in complex with ARF1 GTP form | | 分子名称: | ADP-ribosylation factor 1, ADP-ribosylation factor binding protein GGA1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Shiba, T, Kawasaki, M, Takatsu, H, Nogi, T, Matsugaki, N, Igarashi, N, Suzuki, M, Kato, R, Nakayama, K, Wakatsuki, S. | | 登録日 | 2003-01-05 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport
NAT.STRUCT.BIOL., 10, 2003
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7DHW
 | | Crystal structure of myosin-XI motor domain in complex with ADP-ALF4 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Suzuki, K, Haraguchi, T, Tamanaha, M, Yoshimura, K, Imi, T, Tominaga, M, Sakayama, H, Nishiyama, T, Ito, K, Murata, T. | | 登録日 | 2020-11-17 | | 公開日 | 2021-05-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Discovery of ultrafast myosin, its amino acid sequence, and structural features.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6AGP
 | | Structure of Rac1 in the low-affinity state for Mg2+ | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Toyama, Y, Kontani, K, Katada, T, Shimada, I. | | 登録日 | 2018-08-13 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR.
Sci Adv, 5, 2019
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5LPU
 | | Crystal structure of Annexin A2 complexed with S100A4 | | 分子名称: | Annexin A2, CALCIUM ION, GLYCEROL, ... | | 著者 | Ecsedi, P, Gogl, G, Kiss, B, Nyitray, L. | | 登録日 | 2016-08-15 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
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6BC1
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5CJP
 | | The Structural Basis for Cdc42-Induced Dimerization of IQGAPs | | 分子名称: | Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a, ... | | 著者 | Worthylake, D.K, Boyapati, V.K, LeCour Jr, L. | | 登録日 | 2015-07-14 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.
Structure, 24, 2016
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6ZS2
 | | Crystal Structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in complex with 2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol | | 分子名称: | 1,2-ETHANEDIOL, 2-(6-azanyl-5-piperazin-4-ium-1-yl-pyridazin-3-yl)phenol, Transcription activator BRG1 | | 著者 | Preuss, F, Joerger, A.C, Kraemer, A, Wanior, M, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2020-07-15 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
J.Med.Chem., 63, 2020
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4HBD
 | | Crystal structure of KANK2 ankyrin repeats | | 分子名称: | KN motif and ankyrin repeat domain-containing protein 2, UNKNOWN ATOM OR ION | | 著者 | Xu, C, Tempel, W, Cerovina, T, El Bakkouri, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2012-09-27 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Crystal structure of KANK2 ankyrin repeats
To be Published
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5H64
 | | Cryo-EM structure of mTORC1 | | 分子名称: | Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 | | 著者 | Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H. | | 登録日 | 2016-11-10 | | 公開日 | 2017-01-25 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | 4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1
Protein Cell, 7, 2016
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5C2J
 | | Complex structure of the GAP domain of MgcRacGAP and Cdc42 | | 分子名称: | ALUMINUM FLUORIDE, Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Murayama, K, Kato-Murayama, M, Hosaka, T, Kitamura, T, Yokoyama, S, Shirouzu, M. | | 登録日 | 2015-06-16 | | 公開日 | 2016-06-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of G-protein target alternation of MgcRacGAP by phospholylation
To Be Published
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3EGG
 | | Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Spinophilin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Ragusa, M.J, Page, R, Peti, W. | | 登録日 | 2008-09-10 | | 公開日 | 2010-03-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
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