PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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3KGF	The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan 分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Parker, E.J, Jameson, G.B, Jiao, W, Webby, C.J, Baker, E.N, Baker, H.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) 登録日 2009-10-29 公開日 2010-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis J.Biol.Chem., 285, 2010
3KMO	Crystal Structure of the Human GST Pi C47S/Y108V Double Mutant in Complex with the Ethacrynic Acid-Glutathione Conjugate (Grown in the Absence of the Reducing Agent DTT) 分子名称: CALCIUM ION, ETHACRYNIC ACID, GLUTATHIONE, ... 著者 Parker, L.J. 登録日 2009-11-11 公開日 2010-03-23 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Diuretic drug binding to human glutathione transferase P1-1: potential role of CYS101 revealed in the double mutant C47S/Y108V To be Published
3KO6	Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate 分子名称: METHIONINE SULFOXIDE, UPF0067 GAF domain-containing protein YKL069W 著者 Ma, X.-X, Guo, P.-C, Chen, Y, Zhou, C.-Z. 登録日 2009-11-13 公開日 2010-11-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate To be Published
3KO7	DTD from Plasmodium falciparum in complex with D-Lysine 分子名称: D-LYSINE, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3KOD	DTD from Plasmodium falciparum in complex with D-Serine 分子名称: D-SERINE, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3K9Q	Crystal structure of C151G mutant of Glyceraldehyde 3-phosphate dehydrogenase 1 from Methicillin resistant Staphylococcus aureus (MRSA252) at 2.5 angstrom resolution 分子名称: CHLORIDE ION, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase 1, ... 著者 Mukherjee, S, Dutta, D, Saha, B, Das, A.K. 登録日 2009-10-16 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010
3FY3	Crystal structure of truncated hemolysin A from P. mirabilis 分子名称: Hemolysin 著者 Weaver, T.M, Thompson, J.R, Bailey, L.J, Wawrzyn, G.T, Hocking, J.M, Howard, D.R. 登録日 2009-01-21 公開日 2009-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and functional studies of truncated hemolysin A from Proteus mirabilis. J.Biol.Chem., 284, 2009
2CBJ	Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc 分子名称: CHLORIDE ION, HYALURONIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE 著者 Rao, F.V, Dorfmueller, H.C, Villa, F, Allwood, M, Eggleston, I.M, van Aalten, D.M.F. 登録日 2006-01-05 公開日 2006-02-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis. EMBO J., 25, 2006
3JQE	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-6-(4-methoxyphenyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (DX8) 分子名称: 2-amino-6-(4-methoxyphenyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Tulloch, L.B, Hunter, W.N. 登録日 2009-09-06 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
3FRS	Structure of human IST1(NTD) (residues 1-189)(p43212) 分子名称: GLYCEROL, Uncharacterized protein KIAA0174 著者 Schubert, H.L, Hill, C.P, Bajorek, M, Sundquist, W.I. 登録日 2009-01-08 公開日 2009-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural basis for ESCRT-III protein autoinhibition. Nat.Struct.Mol.Biol., 16, 2009
3G28	Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH 分子名称: GLYCEROL, Gag polyprotein, NITRATE ION 著者 Kingston, R.L. 登録日 2009-01-30 公開日 2009-06-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Proton-linked dimerization of a retroviral capsid protein initiates capsid assembly Structure, 17, 2009
2CDP	Structure of a CBM6 in complex with neoagarohexaose 分子名称: 1,2-ETHANEDIOL, 3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose, BETA-AGARASE 1, ... 著者 Henshaw, J, Horne, A, Van Bueren, A.L, Money, V.A, Bolam, D.N, Czjzek, M, Weiner, R.M, Hutcheson, S.W, Davies, G.J, Boraston, A.B, Gilbert, H.J. 登録日 2006-01-26 公開日 2006-02-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Family 6 Carbohydrate Binding Modules in Beta-Agarases Display Exquisite Selectivity for the Non- Reducing Termini of Agarose Chains. J.Biol.Chem., 281, 2006
2C7V	Structure of Trypanosoma brucei pteridine reductase (PTR1) in ternary complex with cofactor and the antifolate methotrexate 分子名称: ACETATE ION, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Dawson, A, Gibellini, F, Sienkiewicz, N, Fyfe, P.K, McLuskey, K, Fairlamb, A.H, Hunter, W.N. 登録日 2005-11-29 公開日 2006-09-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Reactivity of Trypanosoma Brucei Pteridine Reductase: Inhibition by the Archetypal Antifolate Methotrexate Mol.Microbiol., 61, 2006
8WTQ	HUMAN SQUALENE SYNTHASE IN COMPLEX WITH {1-[2-Chloro-5-(2,2-dimethyl-propyl)-13-(2-methoxy-phenyl)-6-oxo-6,7,10,11-tetrahydro-5H,9H,13H-12-oxa-5,8-diaza-benzocycloundecene-8-carbonyl]-piperidin-4-yl}-acetic acid 分子名称: 2-[1-[[(10~{S})-13-chloranyl-2-(2,2-dimethylpropyl)-10-(2-methoxyphenyl)-3-oxidanylidene-9-oxa-2,5-diazabicyclo[9.4.0]pentadeca-1(15),11,13-trien-5-yl]carbonyl]piperidin-4-yl]ethanoic acid, PHOSPHATE ION, Squalene synthase 著者 Suzuki, M, Haginoya, N, Suzuki, M, Ishigai, Y, Terayama, K, Kanda, A, Sugita, K. 登録日 2023-10-19 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Novel 11-Membered Templates as Squalene Synthase Inhibitors. J.Med.Chem., 67, 2024
8WTR	HUMAN SQUALENE SYNTHASE IN COMPLEX WITH (1S,3R)-3-[2-Chloro-5-(2,2-dimethyl-propyl)-13-(2-methoxy-phenyl)-6,8-dioxo-5,6,7,8,10,11-hexahydro-13H-12-oxa-5,9-diaza-benzocycloundecen-9-yl]-cyclohexanecarboxylic acid 分子名称: (1~{S},3~{R})-3-[(10~{S})-13-chloranyl-2-(2,2-dimethylpropyl)-10-(2-methoxyphenyl)-3,5-bis(oxidanylidene)-9-oxa-2,6-diazabicyclo[9.4.0]pentadeca-1(15),11,13-trien-6-yl]cyclohexane-1-carboxylic acid, PHOSPHATE ION, Squalene synthase 著者 Suzuki, M, Haginoya, N, Suzuki, M, Ishigai, Y, Terayama, K, Kanda, A, Sugita, K. 登録日 2023-10-19 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Novel 11-Membered Templates as Squalene Synthase Inhibitors. J.Med.Chem., 67, 2024
3KM3	Crystal structure of eoxycytidine triphosphate deaminase from anaplasma phagocytophilum at 2.1A resolution 分子名称: Deoxycytidine triphosphate deaminase, IODIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-11-09 公開日 2009-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 SAD phasing using iodide ions in a high-throughput structural genomics environment. J.Struct.Funct.Genom., 12, 2011
3KM8	Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine 分子名称: 9-DEAZAINOSINE, Adenosine deaminase, ZINC ION 著者 Fan, X, Gao, Y. 登録日 2009-11-10 公開日 2010-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Catalytic Mechanism of Adenosine Deaminase from Mouse: An Experimental and Theoretical Study To be Published
3KWC	Oxidized, active structure of the beta-carboxysomal gamma-Carbonic Anhydrase, CcmM 分子名称: CHLORIDE ION, Carbon dioxide concentrating mechanism protein, ISOPROPYL ALCOHOL, ... 著者 Kimber, M.S, Castel, S.E, Pena, K.L. 登録日 2009-12-01 公開日 2010-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of the oxidative activation of the carboxysomal {gamma}-carbonic anhydrase, CcmM. Proc.Natl.Acad.Sci.USA, 107, 2010
3HMN	Crystal structure of human Mps1 catalytic domain in complex with ATP 分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity protein kinase TTK 著者 Chu, M.L.H, Chavas, L.M.G, Williams, D.H, Tabernero, L, Eyers, P.A. 登録日 2009-05-29 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes. Biochemistry, 49, 2010
5ODJ	Single-stranded DNA-binding protein from bacteriophage Enc34 分子名称: CHLORIDE ION, MAGNESIUM ION, Single-stranded DNA-binding protein 著者 Cernooka, E, Rumnieks, J, Kazaks, A, Tars, K. 登録日 2017-07-05 公開日 2017-10-25 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34. Sci Rep, 7, 2017
5ODK	Single-stranded DNA-binding protein from bacteriophage Enc34, C-terminal truncation 分子名称: GLYCEROL, PHOSPHATE ION, single-stranded DNA-binding protein 著者 Cernooka, E, Rumnieks, J, Kazaks, A, Tars, K. 登録日 2017-07-05 公開日 2017-10-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34. Sci Rep, 7, 2017
3HZO	Rv0554 from Mycobacterium tuberculosis - the structure solved from the tetragonal crystal form 分子名称: 1,2-ETHANEDIOL, MALONIC ACID, SODIUM ION, ... 著者 Johnston, J.M, Baker, E.N. 登録日 2009-06-23 公開日 2010-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The structure of Rv0554 from Mycobacterium tuberculosis To be Published
3I0C	Crystal structure of GTB C80S/C196S unliganded 分子名称: ABO glycosyltransferase 著者 Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. 登録日 2009-06-25 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402, 2010
3I0H	Crystal structure of GTB C80S/C196S/C209S unliganded 分子名称: ABO glycosyltransferase 著者 Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. 登録日 2009-06-25 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402, 2010
3K73	Crystal Structure of Phosphate bound Holo Glyceraldehyde-3-phosphate dehydrogenase 1 from MRSA252 at 2.5 Angstrom resolution 分子名称: Glyceraldehyde-3-phosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION 著者 Mukherjee, S, Dutta, D, Saha, B, Das, A.K. 登録日 2009-10-12 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010

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