5EZ6
 
 | | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | | 著者 | Yan, Z, Ma, S, Zhang, Y, Ma, L, Wang, F, Li, J, Miao, L. | | 登録日 | 2015-11-26 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA
To Be Published
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5FI4
 | | Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model | | 分子名称: | GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... | | 著者 | Elling, R.A, Knapp, M.S, Han, W, Daniel, L.M, Xy, Y, Burger, M.T, Ni, Z, Smith, A, Lan, J, Williams, T, Verhagen, J, Huh, K, Merritt, H, Chan, J, Kaufman, S, Voliva, C.F, Pecchi, S. | | 登録日 | 2015-12-22 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model.
Bioorg.Med.Chem.Lett., 26, 2016
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7YYH
 | | Structure of the human CCANdeltaT CENP-A alpha-satellite complex | | 分子名称: | Centromere protein C, Centromere protein H, Centromere protein I, ... | | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | | 登録日 | 2022-02-17 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
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1CC0
 | | CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, rho GDP dissociation inhibitor alpha, ... | | 著者 | Longenecker, K.L, Read, P, Derewenda, U, Dauter, Z, Garrard, S, Walker, L, Somlyo, A.V, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S. | | 登録日 | 1999-03-03 | | 公開日 | 2000-01-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | How RhoGDI binds Rho.
Acta Crystallogr.,Sect.D, 55, 1999
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1CXZ
 | | CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1 | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), ... | | 著者 | Maesaki, R, Ihara, K, Shimizu, T, Kuroda, S, Kaibuchi, K, Hakoshima, T. | | 登録日 | 1999-08-31 | | 公開日 | 1999-10-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.
Mol.Cell, 4, 1999
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3HVQ
 | | Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Neurabin | | 分子名称: | GLYCEROL, MANGANESE (II) ION, Neurabin-1, ... | | 著者 | Critton, D.A, Ragusa, M.J, Page, R, Peti, W. | | 登録日 | 2009-06-16 | | 公開日 | 2010-03-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
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5EPZ
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5GYN
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1B1E
 | | CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT K40Q | | 分子名称: | CITRIC ACID, HYDROLASE ANGIOGENIN | | 著者 | Leonidas, D.D, Acharya, K.R. | | 登録日 | 1998-11-20 | | 公開日 | 1999-04-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth.
J.Mol.Biol., 285, 1999
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2G2B
 | | NMR structure of the human allograft inflammatory factor 1 | | 分子名称: | Allograft inflammatory factor 1 | | 著者 | Song, J, Tyler, R.C, Newman, C.L, Vinarov, D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2006-02-15 | | 公開日 | 2006-02-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the human allograft inflammatory factor 1
To be published
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5H04
 | | Crystal structure of an ADP-ribosylating toxin BECa of a novel binary enterotoxin of C. perfringens with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Binary enterotoxin of Clostridium perfringens component a | | 著者 | Kawahara, K, Yonogi, S, Munetomo, R, Oki, H, Yoshida, T, Ohkubo, T, Kumeda, Y, Matsuda, S, Kodama, T, Iida, T, Nakamura, S. | | 登録日 | 2016-10-03 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.825 Å) | | 主引用文献 | Crystal structure of the ADP-ribosylating component of BEC, the binary enterotoxin of Clostridium perfringens.
Biochem.Biophys.Res.Commun., 480, 2016
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1DPF
 | | CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, RHOA | | 著者 | Shimizu, T, Ihara, K, Maesaki, R, Kuroda, S, Kaibuchi, K, Hakoshima, T. | | 登録日 | 1999-12-27 | | 公開日 | 2000-06-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism.
J.Biol.Chem., 275, 2000
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1DS6
 | | CRYSTAL STRUCTURE OF A RAC-RHOGDI COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2, ... | | 著者 | Scheffzek, K, Stephan, I, Jensen, O.N, Illenberger, D, Gierschik, P. | | 登録日 | 2000-01-07 | | 公開日 | 2000-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI.
Nat.Struct.Biol., 7, 2000
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5H03
 | | Crystal structure of an ADP-ribosylating toxin BECa from C. perfringens | | 分子名称: | Binary enterotoxin of Clostridium perfringens component a | | 著者 | Kawahara, K, Yonogi, S, Munetomo, R, Oki, H, Yoshida, T, Ohkubo, T, Kumeda, Y, Matsuda, S, Kodama, T, Iida, T, Nakamura, S. | | 登録日 | 2016-10-03 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Crystal structure of the ADP-ribosylating component of BEC, the binary enterotoxin of Clostridium perfringens.
Biochem.Biophys.Res.Commun., 480, 2016
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5HPY
 | | Crystal Structure of RhoA.GDP.MgF3-in complex with human Myosin 9b RhoGAP domain | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRIFLUOROMAGNESATE, ... | | 著者 | Yi, F.S, Ren, J.Q, Feng, W. | | 登録日 | 2016-01-21 | | 公開日 | 2016-07-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism
J.Mol.Biol., 428, 2016
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5EOP
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5EM0
 | | Crystal structure of mugwort allergen Art v 4 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Pollen allergen Art v 4.01, SODIUM ION | | 著者 | Offermann, L.R, Perdue, M.L, Chruszcz, M. | | 登録日 | 2015-11-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
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5EV0
 | | Crystal structure of ragweed profilin Amb a 8 in complex with poly-Pro14 | | 分子名称: | PRO-PRO-PRO-PRO-PRO-PRO-PRO-PRO-PRO, Profilin | | 著者 | Offermann, L.R, He, J.Z, Perdue, M.L, Chruszcz, M. | | 登録日 | 2015-11-19 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
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1F60
 | | CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA | | 分子名称: | ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA | | 著者 | Andersen, G.R, Pedersen, L, Valente, L, Kinzy, T.G, Nyborg, J. | | 登録日 | 2000-06-19 | | 公開日 | 2000-07-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
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1LKX
 | | MOTOR DOMAIN OF MYOE, A CLASS-I MYOSIN | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN IE HEAVY CHAIN, ... | | 著者 | Kollmar, M, Durrwang, U, Kliche, W, Manstein, D.J, Kull, F.J. | | 登録日 | 2002-04-26 | | 公開日 | 2002-06-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the motor domain of a class-I myosin.
EMBO J., 21, 2002
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7CUN
 | | The structure of human Integrator-PP2A complex | | 分子名称: | Integrator complex subunit 1, Integrator complex subunit 11, Integrator complex subunit 2, ... | | 著者 | Zheng, H, Qi, Y, Liu, W, Li, J, Wang, J, Xu, Y. | | 登録日 | 2020-08-23 | | 公開日 | 2020-11-25 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
Science, 370, 2020
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6DU8
 | | Human Polycsytin 2-l1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein | | 著者 | Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J. | | 登録日 | 2018-06-20 | | 公開日 | 2018-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Cryo-EM structure of the polycystin 2-l1 ion channel.
Elife, 7, 2018
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1PA7
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1I07
 | | EPS8 SH3 DOMAIN INTERTWINED DIMER | | 分子名称: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | | 著者 | Kishan, K.V.R, Newcomer, M.E. | | 登録日 | 2001-01-29 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
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1I0C
 | | EPS8 SH3 CLOSED MONOMER | | 分子名称: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | | 著者 | Kishan, K.V.R, Newcomer, M.E. | | 登録日 | 2001-01-29 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
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