PDB: 12060 件ウェブページステータス検索Chemie searchBIRD

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7DYY	Crystal structure of VIM-2 MBL in complex with 1-((2-aminobenzo[d]thiazol-6-yl)methyl)-1H-imidazole-2-carboxylic acid 分子名称: 1-[(2-azanyl-1,3-benzothiazol-6-yl)methyl]imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, DI(HYDROXYETHYL)ETHER, ... 著者 Yan, Y.-H, Li, G.-B. 登録日 2021-01-23 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 228, 2022
7DYZ	Crystal structure of VIM-2 MBL in complex with 1-(but-3-en-1-yl)-4-methyl-1H-imidazole-2-carboxylic acid 分子名称: 1-but-3-enyl-4-methyl-imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, GLYCEROL, ... 著者 Yan, Y.-H, Li, G.-B. 登録日 2021-01-23 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 228, 2022
2KYP	Monomeric Human CKIT-2 proto-oncogene promoter quadruplex DNA NMR, 12 structures 分子名称: 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3' 著者 Kuryavyi, V, Phan, A.T, Patel, D.J. 登録日 2010-06-06 公開日 2010-06-30 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter. Nucleic Acids Res., 38, 2010
4UAR	Crystal structure of apo-CbbY from Rhodobacter sphaeroides 分子名称: GLYCEROL, Protein CbbY 著者 Bracher, A, Sharma, A, Starling-Windhof, A, Hartl, F.U, Hayer-Hartl, M. 登録日 2014-08-11 公開日 2014-12-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Degradation of potent Rubisco inhibitor by selective sugar phosphatase. Nat.Plants, 1, 2015
7DZ1	Crystal structure of VIM-2 MBL in complex with 1-benzyl-5-methyl-1H-imidazole-2-carboxylic acid 分子名称: 5-methyl-1-(phenylmethyl)imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION 著者 Yan, Y.-H, Li, G.-B. 登録日 2021-01-23 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.708 Å) 主引用文献 Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 228, 2022
2KV3	Human Regenerating Gene Type IV (REG IV) PROTEIN, P91S mutant 分子名称: Regenerating islet-derived protein 4 著者 Ho, M, Lou, Y, Chen, C. 登録日 2010-03-04 公開日 2010-08-18 最終更新日 2021-11-10 実験手法 SOLUTION NMR 主引用文献 Human RegIV protein adopts a typical C-type lectin fold but binds mannan with two calcium-independent sites. J.Mol.Biol., 402, 2010
4DO5	Pharmacological chaperones for human alpha-N-acetylgalactosaminidase 分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Clark, N.E, Garman, S.C. 登録日 2012-02-09 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Pharmacological chaperones for human alpha-N-acetylgalactosaminidase Proc.Natl.Acad.Sci.USA, 109, 2012
4UFK	Mouse Galactocerebrosidase complexed with dideoxy-imino-lyxitol DIL 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. 登録日 2015-03-17 公開日 2015-03-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.402 Å) 主引用文献 Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
7DZ0	Crystal structure of VIM-2 MBL in complex with 1-(but-3-en-1-yl)-5-methyl-1H-imidazole-2-carboxylic acid 分子名称: 1-but-3-enyl-5-methyl-imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION 著者 Yan, Y.-H, Li, G.-B. 登録日 2021-01-23 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.227 Å) 主引用文献 Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 228, 2022
4UFH	Mouse Galactocerebrosidase complexed with iso-galacto-fagomine IGF 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. 登録日 2015-03-17 公開日 2015-03-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
4MWX	Shanghai N9-zanamivir 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... 著者 Wu, Y, Qi, J.X, Gao, F, Gao, G.F. 登録日 2013-09-25 公開日 2013-11-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses Cell Res., 23, 2013
7FDM	Crystal structure of transcription factor MYB29 in complex with MYC3 分子名称: Transcription factor MYB29, Transcription factor MYC3 著者 Luo, Q, Wang, B. 登録日 2021-07-17 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into partner selection for MYB and bHLH transcription factor complexes. Nat.Plants, 8, 2021
2ZNN	Human PPAR alpha ligand binding domain in complex with a synthetic agonist TIPP703 分子名称: (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid, Peroxisome proliferator-activated receptor alpha 著者 Oyama, T, Toyota, K, Kasuga, J, Miyachi, H, Morikawa, K. 登録日 2008-04-30 公開日 2009-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures Acta Crystallogr.,Sect.D, 65, 2009
7F61	Crystal structure of human histamine receptor H3R in complex with antagonist PF03654746 分子名称: CHOLESTEROL, Histamine H3 receptor, N-ethyl-3-fluoranyl-3-[3-fluoranyl-4-(pyrrolidin-1-ylmethyl)phenyl]cyclobutane-1-carboxamide, ... 著者 Peng, X, Zhang, H. 登録日 2021-06-23 公開日 2022-10-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for recognition of antihistamine drug by human histamine receptor. Nat Commun, 13, 2022
3KPZ	Crystal structure of a novel vitamin D3 analogue, ZK203278 showing dissociated profile 分子名称: (1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,5S)-5-hydroxy-1-methyl-5-(1,3-thiazol-2-yl)pentyl]-7a-methyloctahydro-4H-inden-4-ylidene}ethylidene]-4-methylidenecyclohexane-1,3-diol, Vitamin D3 receptor 著者 Rochel, N, Moras, D. 登録日 2009-11-17 公開日 2011-10-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a vitamin D3 analog, ZK203278, showing dissociated profile. Anticancer Res., 32, 2012
2A89	Monomeric Sarcosine Oxidase: Structure of a covalently flavinylated amine oxidizing enzyme 分子名称: (N5,C4A)-(ALPHA-HYDROXY-PROPANO)-3,4,4A,5-TETRAHYDRO-FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, Monomeric sarcosine oxidase, ... 著者 Chen, Z.-W, Zhao, G, Martinovic, S, Jorns, M.S, Mathews, F.S. 登録日 2005-07-07 公開日 2006-01-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of the sodium borohydride-reduced N-(cyclopropyl)glycine adduct of the flavoenzyme monomeric sarcosine oxidase. Biochemistry, 44, 2005
2A8H	Crystal structure of catalytic domain of TACE with Thiomorpholine Sulfonamide Hydroxamate inhibitor 分子名称: 4-({4-[(4-AMINOBUT-2-YNYL)OXY]PHENYL}SULFONYL)-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE, ADAM 17, ZINC ION 著者 Levin, J.I, Chen, J.M, Laakso, L.M, Du, M, Schmid, J, Xu, W, Cummons, T, Xu, J, Jin, G, Barone, D, Skotnicki, J.S. 登録日 2005-07-08 公開日 2006-02-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Acetylenic TACE inhibitors. Part 3: Thiomorpholine sulfonamide hydroxamates. Bioorg.Med.Chem.Lett., 16, 2006
7FH0	Crystallographic structure of two neutralizing nanobodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... 著者 Zheng, P, Jin, J. 登録日 2021-07-28 公開日 2022-08-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron. Cell Res., 32, 2022
4MWJ	Anhui N9 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... 著者 Wu, Y, Qi, J.X, Gao, F, Gao, G.F. 登録日 2013-09-25 公開日 2013-11-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses Cell Res., 23, 2013
2A9Z	Crystal structure of T. gondii adenosine kinase complexed with N6-dimethyladenosine and AMP-PCP 分子名称: 6N-DIMETHYLADENOSINE, CHLORIDE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Zhang, Y, el Kouni, M.H, Ealick, S.E. 登録日 2005-07-12 公開日 2006-07-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase Acta Crystallogr.,Sect.D, 63, 2007
7FB9	Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) 分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION 著者 Baek, Y, Ha, N.-C. 登録日 2021-07-08 公開日 2022-10-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation. Commun Biol, 5, 2022
4MWW	Shanghai N9-oseltamivir carboxylate 分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Wu, Y, Qi, J.X, Gao, F, Gao, G.F. 登録日 2013-09-25 公開日 2013-11-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses Cell Res., 23, 2013
4UFL	Mouse Galactocerebrosidase complexed with deoxy-galacto-noeurostegine DGN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. 登録日 2015-03-17 公開日 2015-03-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
7FD2	Cryo-EM structure of an alphavirus, Getah virus 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Liu, Z, Liu, C, Wang, A. 登録日 2021-07-15 公開日 2022-08-10 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Structure of infective Getah virus at 2.8 angstrom resolution determined by cryo-electron microscopy. Cell Discov, 8, 2022
1XV9	crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid, and 5b-pregnane-3,20-dione. 分子名称: (5BETA)-PREGNANE-3,20-DIONE, Orphan nuclear receptor NR1I3, PENTADECANOIC ACID, ... 著者 Xu, R.X, Lambert, M.H, Wisely, B.B, Warren, E.N, Weinert, E.E, Waitt, G.M, Williams, J.D, Moore, L.B, Willson, T.M, Moore, J.T. 登録日 2004-10-27 公開日 2004-12-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer. Mol.Cell, 16, 2004

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