4O22
 
 | | Binary complex of metal-free PKAc with SP20. | | 分子名称: | Phosphorylated peptide pSP20., cAMP-dependent protein kinase catalytic subunit alpha. | | 著者 | Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S.S. | | 登録日 | 2013-12-16 | | 公開日 | 2014-05-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
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2L8K
 | | NMR Structure of the Arterivirus nonstructural protein 7 alpha (nsp7 alpha) | | 分子名称: | Non-structural protein 7 | | 著者 | Conte, M.R, Gaudin, C, Manolaridis, I, Tucker, P.W, Kelly, G. | | 登録日 | 2011-01-19 | | 公開日 | 2011-07-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Genetic Analysis of the Arterivirus Nonstructural Protein 7{alpha}.
J.Virol., 85, 2011
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5XSQ
 | | Crystal Structure of the Marburg Virus Nucleoprotein Core Domain Chaperoned by a VP35 Peptide | | 分子名称: | Nucleoprotein, Peptide from Polymerase cofactor VP35 | | 著者 | Zhu, T, Song, H, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2017-06-15 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the Marburg Virus Nucleoprotein Core Domain Chaperoned by a VP35 Peptide Reveals a Conserved Drug Target for Filovirus
J. Virol., 91, 2017
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1EV1
 | | ECHOVIRUS 1 | | 分子名称: | ECHOVIRUS 1, MYRISTIC ACID, PALMITIC ACID | | 著者 | Wien, M.W, Filman, D.J, Hogle, J.M. | | 登録日 | 1997-12-02 | | 公開日 | 1999-01-27 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | Structure determination of echovirus 1.
Acta Crystallogr.,Sect.D, 54, 1998
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4HKC
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2H9H
 | | An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors | | 分子名称: | Hepatitis A virus protease 3C, N-[(BENZYLOXY)CARBONYL]-L-ALANINE, Three residue peptide | | 著者 | Yin, J, Cherney, M.M, Bergmann, E.M, James, M.N. | | 登録日 | 2006-06-09 | | 公開日 | 2006-08-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | An Episulfide Cation (Thiiranium Ring) Trapped in the Active Site of HAV 3C Proteinase Inactivated by Peptide-based Ketone Inhibitors.
J.Mol.Biol., 361, 2006
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7O3D
 | | Cooperation between the intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly | | 分子名称: | Transcription elongation factor SPT6 | | 著者 | Kasiliauskaite, A, Kubicek, K, Klumpler, T, Zanova, M, Zapletal, D, Novacek, J, Stefl, R. | | 登録日 | 2021-04-01 | | 公開日 | 2022-04-13 | | 最終更新日 | 2022-06-15 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Cooperation between intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly.
Nucleic Acids Res., 50, 2022
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7O6B
 | | Cooperation between the intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly | | 分子名称: | Transcription elongation factor SPT6 | | 著者 | Kasiliauskaite, A, Kubicek, K, Klumpler, T, Zanova, M, Zapletal, D, Novacek, J, Stefl, R. | | 登録日 | 2021-04-09 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | Cooperation between intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly.
Nucleic Acids Res., 50, 2022
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6VKQ
 | | Crystal Structure of human PARP-1 CAT domain bound to inhibitor EB-47 | | 分子名称: | 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Poly [ADP-ribose] polymerase 1, SULFATE ION | | 著者 | Steffen, J.D, Pascal, J.M. | | 登録日 | 2020-01-21 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
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6VKK
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2MPL
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6VKO
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4PUR
 | | Crystal structure of MglA from Francisella tularensis | | 分子名称: | D-MALATE, Macrophage growth locus, subunit A | | 著者 | Cuthbert, B.J, Schumacher, M.A, Brennan, R.G. | | 登録日 | 2014-03-13 | | 公開日 | 2015-06-24 | | 最終更新日 | 2021-01-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural and Biochemical Characterization of the Francisella tularensis Pathogenicity Regulator, Macrophage Locus Protein A (MglA).
Plos One, 10, 2015
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4MG3
 | | Crystal Structural Analysis of 2A Protease from Coxsackievirus A16 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PENTAETHYLENE GLYCOL, Protease 2A, ... | | 著者 | Sun, Y, Wang, X, Dang, M, Yuan, S. | | 登録日 | 2013-08-28 | | 公開日 | 2014-03-26 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | An open conformation determined by a structural switch for 2A protease from coxsackievirus A16.
Protein Cell, 4, 2013
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3W95
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1H8T
 | | Echovirus 11 | | 分子名称: | 12-AMINO-DODECANOIC ACID, ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ... | | 著者 | Stuart, A, McKee, T, Williams, P.A, Harley, C, Stuart, D.I, Brown, T.D.K, Lea, S.M. | | 登録日 | 2001-02-15 | | 公開日 | 2002-07-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection
J.Virol., 76, 2002
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5FM7
 | | Double-heterohexameric rings of full-length Rvb1(ADP)Rvb2(ADP) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RVB1, RVB2 | | 著者 | Silva-Martin, N, Dauden, M.I, Glatt, S, Hoffmann, N.A, Mueller, C.W. | | 登録日 | 2015-11-02 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | | 主引用文献 | The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight Into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex.
Plos One, 11, 2016
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1YRN
 | | CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA | | 分子名称: | DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*TP*AP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*TP*AP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT A1 HOMEODOMAIN), ... | | 著者 | Li, T, Stark, M.R, Johnson, A.D, Wolberger, C. | | 登録日 | 1995-11-02 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA.
Science, 270, 1995
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5H2W
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8G94
 | | Structure of CD69-bound S1PR1 coupled to heterotrimeric Gi | | 分子名称: | Early activation antigen CD69, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Chen, H, Li, X. | | 登録日 | 2023-02-21 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Transmembrane protein CD69 acts as an S1PR1 agonist.
Elife, 12, 2023
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5FM6
 | | Double-heterohexameric rings of full-length Rvb1(ADP)Rvb2(apo) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, RVB1, ... | | 著者 | Silva-Martin, N, Dauden, M.I, Glatt, S, Hoffmann, N.A, Mueller, C.W. | | 登録日 | 2015-11-02 | | 公開日 | 2016-01-20 | | 実験手法 | X-RAY DIFFRACTION (2.997 Å) | | 主引用文献 | The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight Into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex.
Plos One, 11, 2016
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1KXA
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7M7Q
 | | Human DNA Pol eta S113A with dT-ended primer and dAMPNPP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M81
 | | Human DNA Pol eta with dA-ended primer and dATP: in crystallo reaction for 100 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M82
 | | Human DNA Pol eta with dA-ended primer and dATP: in crystallo reaction for 300 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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