6WT9
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![BU of 6wt9 by Molmil](/molmil-images/mine/6wt9) | Structure of STING-associated CdnE c-di-GMP synthase from Capnocytophaga granulosa | 分子名称: | NTP_transf_2 domain-containing protein | 著者 | Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J. | 登録日 | 2020-05-01 | 公開日 | 2020-09-09 | 最終更新日 | 2020-10-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | STING cyclic dinucleotide sensing originated in bacteria. Nature, 586, 2020
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6D9M
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![BU of 6d9m by Molmil](/molmil-images/mine/6d9m) | T4-Lysozyme fusion to Geobacter GGDEF | 分子名称: | ACETATE ION, Fusion protein of Endolysin,Response receiver sensor diguanylate cyclase, GAF domain-containing, ... | 著者 | Hallberg, Z, Doxzen, K, Kranzusch, P.J, Hammond, M. | 登録日 | 2018-04-30 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration. Elife, 8, 2019
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3S6A
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![BU of 3s6a by Molmil](/molmil-images/mine/3s6a) | |
4U5T
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![BU of 4u5t by Molmil](/molmil-images/mine/4u5t) | |
3D0S
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5MBD
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![BU of 5mbd by Molmil](/molmil-images/mine/5mbd) | Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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5MBJ
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![BU of 5mbj by Molmil](/molmil-images/mine/5mbj) | Structure of a bacterial light-regulated adenylyl cyclase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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5MBG
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![BU of 5mbg by Molmil](/molmil-images/mine/5mbg) | Structure of a bacterial light-regulated adenylyl cyclase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, IODIDE ION | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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5MBC
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![BU of 5mbc by Molmil](/molmil-images/mine/5mbc) | Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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5MBB
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![BU of 5mbb by Molmil](/molmil-images/mine/5mbb) | Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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5MBK
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![BU of 5mbk by Molmil](/molmil-images/mine/5mbk) | Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Beta subunit of photoactivated adenylyl cyclase, MAGNESIUM ION | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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7WN7
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![BU of 7wn7 by Molmil](/molmil-images/mine/7wn7) | Crystal structure of HearNPV P26 | 分子名称: | CHLORIDE ION, SULFATE ION, p26 | 著者 | Kuang, W, Hu, Z, Gong, P. | 登録日 | 2022-01-17 | 公開日 | 2022-11-23 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Dual roles and evolutionary implications of P26/poxin in antagonizing intracellular cGAS-STING and extracellular melanization immunity. Nat Commun, 13, 2022
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7XNE
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![BU of 7xne by Molmil](/molmil-images/mine/7xne) | Crystal structure of CBP bromodomain liganded with Y08284 | 分子名称: | CREB-binding protein, GLYCEROL, N-[3-(1-cyclopropylpyrazol-4-yl)-2-fluoranyl-5-[(1S)-1-oxidanylethyl]phenyl]-3-ethanoyl-7-methoxy-indolizine-1-carboxamide | 著者 | Xiang, Q, Wang, C, Wu, T, Zhang, C, Hu, Q, Luo, G, Hu, J, Zhuang, X, Zou, L, Shen, H, Wu, X, Zhang, Y, Kong, X, Xu, Y. | 登録日 | 2022-04-28 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J.Med.Chem., 65, 2022
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5NBY
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![BU of 5nby by Molmil](/molmil-images/mine/5nby) | Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2017-03-02 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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5MBE
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![BU of 5mbe by Molmil](/molmil-images/mine/5mbe) | Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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5MBH
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![BU of 5mbh by Molmil](/molmil-images/mine/5mbh) | Structure of a bacterial light-regulated adenylyl cyclase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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5M27
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![BU of 5m27 by Molmil](/molmil-images/mine/5m27) | Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CALCIUM ION, CHLORIDE ION, ... | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-10-12 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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1L8C
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![BU of 1l8c by Molmil](/molmil-images/mine/1l8c) | STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE | 分子名称: | CREB-binding protein, Hypoxia-inducible factor 1 alpha, ZINC ION | 著者 | Dames, S.A, Martinez-Yamout, M, De Guzman, R.N, Dyson, H.J, Wright, P.E. | 登録日 | 2002-03-19 | 公開日 | 2002-04-10 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response. Proc.Natl.Acad.Sci.USA, 99, 2002
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5M2A
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![BU of 5m2a by Molmil](/molmil-images/mine/5m2a) | Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-10-12 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
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2KJE
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![BU of 2kje by Molmil](/molmil-images/mine/2kje) | NMR structure of CBP TAZ2 and adenoviral E1A complex | 分子名称: | CREB-binding protein, Early E1A 32 kDa protein, ZINC ION | 著者 | Ferreon, J.C, Martinez-Yamout, M, Dyson, H, Wright, P.E. | 登録日 | 2009-05-27 | 公開日 | 2009-09-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein. Proc.Natl.Acad.Sci.USA, 106, 2009
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6XB6
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2ZCW
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![BU of 2zcw by Molmil](/molmil-images/mine/2zcw) | Crystal Structure of TTHA1359, a Transcriptional Regulator, CRP/FNR family from Thermus thermophilus HB8 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Transcriptional regulator, FNR/CRP family | 著者 | Agari, Y, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-11-13 | 公開日 | 2007-12-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Global gene expression mediated by Thermus thermophilus SdrP, a CRP/FNR family transcriptional regulator Mol.Microbiol., 70, 2008
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2IZX
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![BU of 2izx by Molmil](/molmil-images/mine/2izx) | Molecular Basis of AKAP Specificity for PKA Regulatory Subunits | 分子名称: | AKAP-IS, CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT, DITHIANE DIOL | 著者 | Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D. | 登録日 | 2006-07-27 | 公開日 | 2006-11-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Molecular Basis of Akap Specificity for Pka Regulatory Subunits. Mol.Cell, 24, 2006
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2IZY
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![BU of 2izy by Molmil](/molmil-images/mine/2izy) | Molecular Basis of AKAP Specificity for PKA Regulatory Subunits | 分子名称: | CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT II | 著者 | Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D. | 登録日 | 2006-07-27 | 公開日 | 2006-11-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular Basis of Akap Specificity for Pka Regululatory Subunits Mol.Cell, 24, 2006
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1HCK
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![BU of 1hck by Molmil](/molmil-images/mine/1hck) | HUMAN CYCLIN-DEPENDENT KINASE 2 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, HUMAN CYCLIN-DEPENDENT KINASE 2, MAGNESIUM ION | 著者 | Schulze-Gahmen, U, De Bondt, H.L, Kim, S.-H. | 登録日 | 1996-06-03 | 公開日 | 1996-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J.Med.Chem., 39, 1996
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