PDB: 731 件ウェブページステータス検索Chemie searchBIRD

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6WT9	Structure of STING-associated CdnE c-di-GMP synthase from Capnocytophaga granulosa 分子名称: NTP_transf_2 domain-containing protein 著者 Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J. 登録日 2020-05-01 公開日 2020-09-09 最終更新日 2020-10-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 STING cyclic dinucleotide sensing originated in bacteria. Nature, 586, 2020
6D9M	T4-Lysozyme fusion to Geobacter GGDEF 分子名称: ACETATE ION, Fusion protein of Endolysin,Response receiver sensor diguanylate cyclase, GAF domain-containing, ... 著者 Hallberg, Z, Doxzen, K, Kranzusch, P.J, Hammond, M. 登録日 2018-04-30 公開日 2019-04-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration. Elife, 8, 2019
3S6A	Fic protein from NEISSERIA MENINGITIDIS in complex with AMPPNP 分子名称: Cell filamentation protein Fic-related protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Stanger, F, Goepfert, A, Schirmer, T. 登録日 2011-05-25 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482, 2012
4U5T	Crystal Structure of VBP Leucine Zipper with Bound Arylstibonic Acid 分子名称: (2Z)-3-{3-[dihydroxy(oxido)-lambda~5~-stibanyl]phenyl}prop-2-enoic acid, VBP leucine zipper 著者 Stagno, J.R, Ji, X. 登録日 2014-07-25 公開日 2014-08-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 P6981, an arylstibonic acid, is a novel low nanomolar inhibitor of cAMP response element-binding protein binding to DNA. Mol.Pharmacol., 82, 2012
3D0S	cAMP receptor protein from m.tuberculosis, cAMP-free form 分子名称: CHLORIDE ION, TRANSCRIPTIONAL REGULATORY PROTEIN 著者 Gallagher, D.T, Robinson, H, Reddy, P.T. 登録日 2008-05-02 公開日 2009-02-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of cAMP receptor protein from M. tuberculosis in the unliganded form To be Published
5MBD	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
5MBJ	Structure of a bacterial light-regulated adenylyl cyclase 分子名称: Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
5MBG	Structure of a bacterial light-regulated adenylyl cyclase 分子名称: Beta subunit of photoactivated adenylyl cyclase, IODIDE ION 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
5MBC	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
5MBB	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
5MBK	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Beta subunit of photoactivated adenylyl cyclase, MAGNESIUM ION 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
7WN7	Crystal structure of HearNPV P26 分子名称: CHLORIDE ION, SULFATE ION, p26 著者 Kuang, W, Hu, Z, Gong, P. 登録日 2022-01-17 公開日 2022-11-23 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Dual roles and evolutionary implications of P26/poxin in antagonizing intracellular cGAS-STING and extracellular melanization immunity. Nat Commun, 13, 2022
7XNE	Crystal structure of CBP bromodomain liganded with Y08284 分子名称: CREB-binding protein, GLYCEROL, N-[3-(1-cyclopropylpyrazol-4-yl)-2-fluoranyl-5-[(1S)-1-oxidanylethyl]phenyl]-3-ethanoyl-7-methoxy-indolizine-1-carboxamide 著者 Xiang, Q, Wang, C, Wu, T, Zhang, C, Hu, Q, Luo, G, Hu, J, Zhuang, X, Zou, L, Shen, H, Wu, X, Zhang, Y, Kong, X, Xu, Y. 登録日 2022-04-28 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J.Med.Chem., 65, 2022
5NBY	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2017-03-02 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
5MBE	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
5MBH	Structure of a bacterial light-regulated adenylyl cyclase 分子名称: Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
5M27	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: Beta subunit of photoactivated adenylyl cyclase, CALCIUM ION, CHLORIDE ION, ... 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-10-12 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
1L8C	STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE 分子名称: CREB-binding protein, Hypoxia-inducible factor 1 alpha, ZINC ION 著者 Dames, S.A, Martinez-Yamout, M, De Guzman, R.N, Dyson, H.J, Wright, P.E. 登録日 2002-03-19 公開日 2002-04-10 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response. Proc.Natl.Acad.Sci.USA, 99, 2002
5M2A	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-10-12 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
2KJE	NMR structure of CBP TAZ2 and adenoviral E1A complex 分子名称: CREB-binding protein, Early E1A 32 kDa protein, ZINC ION 著者 Ferreon, J.C, Martinez-Yamout, M, Dyson, H, Wright, P.E. 登録日 2009-05-27 公開日 2009-09-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein. Proc.Natl.Acad.Sci.USA, 106, 2009
6XB6	Structure of Danaus plexippus poxin cGAMP nuclease 分子名称: Poxin 著者 Eaglesham, J.B, McCarty, K.L, Kranzusch, P.J. 登録日 2020-06-05 公開日 2020-11-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife, 9, 2020
2ZCW	Crystal Structure of TTHA1359, a Transcriptional Regulator, CRP/FNR family from Thermus thermophilus HB8 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Transcriptional regulator, FNR/CRP family 著者 Agari, Y, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-11-13 公開日 2007-12-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Global gene expression mediated by Thermus thermophilus SdrP, a CRP/FNR family transcriptional regulator Mol.Microbiol., 70, 2008
2IZX	Molecular Basis of AKAP Specificity for PKA Regulatory Subunits 分子名称: AKAP-IS, CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT, DITHIANE DIOL 著者 Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D. 登録日 2006-07-27 公開日 2006-11-08 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Molecular Basis of Akap Specificity for Pka Regulatory Subunits. Mol.Cell, 24, 2006
2IZY	Molecular Basis of AKAP Specificity for PKA Regulatory Subunits 分子名称: CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT II 著者 Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D. 登録日 2006-07-27 公開日 2006-11-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular Basis of Akap Specificity for Pka Regululatory Subunits Mol.Cell, 24, 2006
1HCK	HUMAN CYCLIN-DEPENDENT KINASE 2 分子名称: ADENOSINE-5'-TRIPHOSPHATE, HUMAN CYCLIN-DEPENDENT KINASE 2, MAGNESIUM ION 著者 Schulze-Gahmen, U, De Bondt, H.L, Kim, S.-H. 登録日 1996-06-03 公開日 1996-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J.Med.Chem., 39, 1996

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