PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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7NCG	Type 2A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2 分子名称: Alpha-synuclein 著者 Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W. 登録日 2021-01-28 公開日 2021-02-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy. Febs Open Bio, 11, 2021
7NCI	Type 2B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1 分子名称: Alpha-synuclein 著者 Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W. 登録日 2021-01-28 公開日 2021-02-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy. Febs Open Bio, 11, 2021
7NCJ	Type 2AB alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1 分子名称: Alpha-synuclein 著者 Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W. 登録日 2021-01-28 公開日 2021-02-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy. Febs Open Bio, 11, 2021
7NCH	Type 1B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1 分子名称: Alpha-synuclein 著者 Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W. 登録日 2021-01-28 公開日 2021-02-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy. Febs Open Bio, 11, 2021
7NCK	Type 3 alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 5 分子名称: Alpha-synuclein 著者 Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W. 登録日 2021-01-28 公開日 2021-02-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy. Febs Open Bio, 11, 2021
7NCA	Type 1A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2 分子名称: Alpha-synuclein 著者 Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W. 登録日 2021-01-28 公開日 2021-02-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy. Febs Open Bio, 11, 2021
5FDS	Crystal structure of the monomeric allergen profilin (Hev b 8) 分子名称: GLYCEROL, Profilin-2, SULFATE ION 著者 Mares-Mejia, I, Rodriguez-Romero, A. 登録日 2015-12-16 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms. Sci Rep, 6, 2016
5FI1	Crystal Structure of the P-Rex1 DH/PH tandem in complex with Cdc42 分子名称: Cell division control protein 42 homolog, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein 著者 Cash, J.N, Tesmer, J.J.G. 登録日 2015-12-22 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.203 Å) 主引用文献 Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. Structure, 24, 2016
6V6V	Crystal structure of oncogenic RhoA mutant G14V complexed with GDP 分子名称: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Lin, Y, Zheng, Y. 登録日 2019-12-06 公開日 2020-12-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of an inactive conformation of GTP-bound RhoA GTPase. Structure, 29, 2021
7A5P	Human C Complex Spliceosome - Medium-resolution PERIPHERY 分子名称: Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ... 著者 Bertram, K, Kastner, B. 登録日 2020-08-21 公開日 2020-10-14 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome. Mol.Cell, 80, 2020
5FEG	Crystal structure of the dimeric allergen profilin (Hev b 8) 分子名称: Profilin-2 著者 Mares-Mejia, I, Rodriguez-Romero, A. 登録日 2015-12-17 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms. Sci Rep, 6, 2016
8QZZ	Crystal structure of human eIF2 alpha-gamma complexed with PPP1R15A_420-452 分子名称: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Yan, Y, Ron, D. 登録日 2023-10-30 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Substrate recruitment via eIF2 gamma enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proc.Natl.Acad.Sci.USA, 121, 2024
7O0B	TRIM3 Filamin domain 分子名称: Tripartite motif-containing protein 3 著者 Williams, F.P, Yikilmazsoy, A, Hennig, J. 登録日 2021-03-26 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 TRIM3 Filamin domain To be published
6V6M	Crystal structure of an inactive state of GMPPNP-bound RhoA 分子名称: 1,4-DIETHYLENE DIOXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Lin, Y, Zheng, Y. 登録日 2019-12-05 公開日 2020-12-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Structure of an inactive conformation of GTP-bound RhoA GTPase. Structure, 29, 2021
6V6U	Crystal structure of RhoA-GDP with novel Switch I conformation 分子名称: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Lin, Y, Zheng, Y. 登録日 2019-12-06 公開日 2020-12-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Structure of an inactive conformation of GTP-bound RhoA GTPase. Structure, 29, 2021
8QJR	BRG1 bromodomain in complex with VBC via compound 17 分子名称: (2S,4R)-1-[(2R)-2-[3-[2-[4-[3-[4-[(1R,5S)-3-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]pyridin-2-yl]oxycyclobutyl]oxypiperidin-1-yl]ethoxy]-1,2-oxazol-5-yl]-3-methyl-butanoyl]-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, CHLORIDE ION, Elongin-B, ... 著者 Kerry, P.S, Hole, A.J, Perez-Dorado, J.I. 登録日 2023-09-13 公開日 2024-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. J.Med.Chem., 67, 2024
8QJT	BRM (SMARCA2) Bromodomain in complex with ligand 10 分子名称: 2-[6-azanyl-5-[(1R,5S)-8-[2-(2-methoxyethoxy)pyridin-4-yl]-3,8-diazabicyclo[3.2.1]octan-3-yl]pyridazin-3-yl]phenol, CHLORIDE ION, Probable global transcription activator SNF2L2, ... 著者 Kerry, P.S, Hole, A.J, Perez-Dorado, J.I. 登録日 2023-09-13 公開日 2024-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.568 Å) 主引用文献 PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. J.Med.Chem., 67, 2024
8Q62	Early closed conformation of the g-tubulin ring complex 分子名称: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... 著者 Llorca, O, Serna, M, Fernandez-Leiro, R. 登録日 2023-08-10 公開日 2024-02-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.72 Å) 主引用文献 Transition of human gamma-tubulin ring complex into a closed conformation during microtubule nucleation. Science, 383, 2024
8SKY	Crystal structure of YisK from Bacillus subtilis in complex with oxalate 分子名称: Fumarylacetoacetate hydrolase family protein, MANGANESE (II) ION, OXALATE ION 著者 Krieger, I.V, Chemelewski, V, Guo, T, Sperber, A, Herman, J, Sacchettini, J.C. 登録日 2023-04-20 公開日 2023-11-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization. J.Bacteriol., 206, 2024
8SCB	Terminating ribosome with SRI-41315 分子名称: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... 著者 Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. 登録日 2023-04-05 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structure and consequences of eRF1 glued to the ribosomal decoding center To Be Published
5KE1	Structure of a C-terminal fragment of the IcsA/VirG passenger-domain 分子名称: NICKEL (II) ION, Outer membrane protein IcsA autotransporter 著者 Leupold, S, Scrima, A. 登録日 2016-06-09 公開日 2017-03-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the architecture of the Shigella flexneri virulence factor IcsA/VirG and motifs involved in polar distribution and secretion. J. Struct. Biol., 198, 2017
5KY6	Human muscle fructose-1,6-bisphosphate aldolase 分子名称: Fructose-bisphosphate aldolase A 著者 Wisniewski, J, Barciszewski, J, Jaskolski, M, Rakus, D. 登録日 2016-07-21 公開日 2017-06-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.941 Å) 主引用文献 Crystal structure of human muscle aldolase To Be Published
5M70	Crystal Structure of human RhoGAP mutated in its arginin finger (R85A) in complex with RhoA.GDP.AlF4- human 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 1, ... 著者 Pellegrini, E, Bowler, M.W. 登録日 2016-10-26 公開日 2017-05-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Assessing the Influence of Mutation on GTPase Transition States by Using X-ray Crystallography, (19) F NMR, and DFT Approaches. Angew. Chem. Int. Ed. Engl., 56, 2017
5M9Q	Human angiogenin PD variant R95Q 分子名称: Angiogenin, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... 著者 Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R. 登録日 2016-11-02 公開日 2017-02-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Sci Rep, 7, 2017
5M9T	Human angiogenin ALS variant H114R 分子名称: Angiogenin, BORATE ION, GLYCEROL 著者 Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R. 登録日 2016-11-02 公開日 2017-02-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Sci Rep, 7, 2017

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