4ORA
| Crystal structure of a human calcineurin mutant | 分子名称: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | 著者 | Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | 登録日 | 2014-02-11 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.747 Å) | 主引用文献 | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
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4YOL
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5QSD
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z54571979 | 分子名称: | N-{4-[(pyrimidin-2-yl)oxy]phenyl}acetamide, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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5QS9
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z48847594 | 分子名称: | N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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5QSC
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z300245038 | 分子名称: | N-[(3-fluorophenyl)methyl]-N-methylsulfuric diamide, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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7CTG
| Human Origin Recognition Complex, ORC1-5 State I | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | 著者 | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | 登録日 | 2020-08-18 | 公開日 | 2021-01-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
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4YOZ
| p107 pocket domain in complex with HPV E7 peptide | 分子名称: | HPV E7 peptide, Retinoblastoma-like protein 1,Retinoblastoma-like protein 1, SULFATE ION | 著者 | Liban, T.J, Guiley, K.Z, Felthousen, J.G, Ramanan, P, Litovchick, L, Rubin, S.M. | 登録日 | 2015-03-12 | 公開日 | 2015-06-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Structural mechanisms of DREAM complex assembly and regulation. Genes Dev., 29, 2015
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5QSE
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2017168803 | 分子名称: | (2S)-2-[(3-fluoropyridin-2-yl)(methyl)amino]propan-1-ol, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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4YOS
| p107 pocket domain complexed with LIN52 peptide | 分子名称: | 1,2-ETHANEDIOL, Protein lin-52 homolog, Retinoblastoma-like protein 1,Retinoblastoma-like protein 1, ... | 著者 | Guiley, K.Z, Liban, T.J, Felthousen, J.G, Ramanan, P, Tripathi, S, Litovchick, L, Rubin, S.M. | 登録日 | 2015-03-12 | 公開日 | 2015-05-27 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural mechanisms of DREAM complex assembly and regulation. Genes Dev., 29, 2015
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5QSF
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434814 | 分子名称: | 3-(diethylamino)phenol, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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5QSI
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z933326822 | 分子名称: | 3-(benzyloxy)aniline, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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4P2P
| AN INDEPENDENT CRYSTALLOGRAPHIC REFINEMENT OF PORCINE PHOSPHOLIPASE A2 AT 2.4 ANGSTROMS RESOLUTION | 分子名称: | CALCIUM ION, PHOSPHOLIPASE A2 | 著者 | Finzel, B.C, Ohlendorf, D.H, Weber, P.C, Salemme, F.R. | 登録日 | 1991-10-22 | 公開日 | 1992-01-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | An independent crystallographic refinement of porcine phospholipase A2 at 2.4 A resolution Acta Crystallogr.,Sect.B, 47, 1991
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5QSB
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434874 | 分子名称: | 1-{[4-(propan-2-yl)phenyl]methyl}piperidin-4-ol, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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4A1X
| Co-Complex structure of NS3-4A protease with the inhibitory peptide CP5-46-A (Synchrotron data) | 分子名称: | CHLORIDE ION, CP5-46-A PEPTIDE, NONSTRUCTURAL PROTEIN 4A, ... | 著者 | Schmelz, S, Kuegler, J, Collins, J, Heinz, D. | 登録日 | 2011-09-20 | 公開日 | 2012-09-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants. J.Biol.Chem., 287, 2012
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5QSH
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434868 | 分子名称: | 1-ethyl-N-(2-fluorophenyl)piperidin-4-amine, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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5QT0
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z321318226 | 分子名称: | N-(4-methoxyphenyl)-N'-pyridin-4-ylurea, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-26 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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6ZFD
| 14-3-3 zeta bound to the phosphorylated 18E6 C-terminus | 分子名称: | 14-3-3 protein zeta/delta,Protein E6, GLYCEROL | 著者 | Gogl, G, Tugaeva, K.V, Sluchanko, N.N, Trave, G. | 登録日 | 2020-06-17 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms. Nat Commun, 12, 2021
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5QSA
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434778 | 分子名称: | 2-(trifluoromethoxy)benzoic acid, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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6UHC
| CryoEM structure of human Arp2/3 complex with bound NPFs | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | 著者 | Zimmet, A, van Eeuwen, T, Dominguez, R. | 登録日 | 2019-09-27 | 公開日 | 2020-07-01 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism. Sci Adv, 6, 2020
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4A1V
| Co-Complex structure of NS3-4A protease with the optimized inhibitory peptide CP5-46A-4D5E | 分子名称: | CHLORIDE ION, CP5-46A-4D5E, NON-STRUCTURAL PROTEIN 4A, ... | 著者 | Schmelz, S, Kuegler, J, Collins, J, Heinz, D.W. | 登録日 | 2011-09-20 | 公開日 | 2012-09-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants. J.Biol.Chem., 287, 2012
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6ZFG
| 14-3-3 zeta chimera with 18E6 and fusicoccin | 分子名称: | 14-3-3 protein zeta/delta,Protein E6, FUSICOCCIN, GLYCEROL | 著者 | Gogl, G, Tugaeva, K, Sluchanko, N.N, Trave, G. | 登録日 | 2020-06-17 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms. Nat Commun, 12, 2021
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5QSG
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434903 | 分子名称: | N-[4-(4-methylpiperazin-1-yl)phenyl]acetamide, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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6QHL
| 14-3-3 sigma with RelA/p65 binding site pS45 | 分子名称: | 14-3-3 protein sigma, GLYCEROL, Transcription factor p65 | 著者 | Wolter, M, Ottmann, C. | 登録日 | 2019-01-16 | 公開日 | 2020-05-13 | 最終更新日 | 2020-12-30 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products. J.Am.Chem.Soc., 142, 2020
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5QS8
| PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z1432018343 | 分子名称: | (2S)-2-[(5-chloro-3-fluoropyridin-2-yl)amino]propan-1-ol, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-05-25 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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4ZLT
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