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4ORA
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BU of 4ora by Molmil
Crystal structure of a human calcineurin mutant
分子名称: CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ...
著者Li, S.J, Wang, J, Wu, J.W, Wang, Z.X.
登録日2014-02-11
公開日2015-05-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.747 Å)
主引用文献Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published
4YOL
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BU of 4yol by Molmil
Human fibroblast growth factor-1 C16S/A66C/C117A/P134A
分子名称: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE
著者Xia, X, Blaber, M.
登録日2015-03-11
公開日2016-03-16
最終更新日2019-02-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application.
J.Pharm.Sci., 105, 2016
5QSD
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BU of 5qsd by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z54571979
分子名称: N-{4-[(pyrimidin-2-yl)oxy]phenyl}acetamide, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QS9
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BU of 5qs9 by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z48847594
分子名称: N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QSC
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BU of 5qsc by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z300245038
分子名称: N-[(3-fluorophenyl)methyl]-N-methylsulfuric diamide, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献PanDDA analysis group deposition
To Be Published
7CTG
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BU of 7ctg by Molmil
Human Origin Recognition Complex, ORC1-5 State I
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
著者Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
登録日2020-08-18
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
4YOZ
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BU of 4yoz by Molmil
p107 pocket domain in complex with HPV E7 peptide
分子名称: HPV E7 peptide, Retinoblastoma-like protein 1,Retinoblastoma-like protein 1, SULFATE ION
著者Liban, T.J, Guiley, K.Z, Felthousen, J.G, Ramanan, P, Litovchick, L, Rubin, S.M.
登録日2015-03-12
公開日2015-06-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.245 Å)
主引用文献Structural mechanisms of DREAM complex assembly and regulation.
Genes Dev., 29, 2015
5QSE
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BU of 5qse by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2017168803
分子名称: (2S)-2-[(3-fluoropyridin-2-yl)(methyl)amino]propan-1-ol, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献PanDDA analysis group deposition
To Be Published
4YOS
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BU of 4yos by Molmil
p107 pocket domain complexed with LIN52 peptide
分子名称: 1,2-ETHANEDIOL, Protein lin-52 homolog, Retinoblastoma-like protein 1,Retinoblastoma-like protein 1, ...
著者Guiley, K.Z, Liban, T.J, Felthousen, J.G, Ramanan, P, Tripathi, S, Litovchick, L, Rubin, S.M.
登録日2015-03-12
公開日2015-05-27
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural mechanisms of DREAM complex assembly and regulation.
Genes Dev., 29, 2015
5QSF
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BU of 5qsf by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434814
分子名称: 3-(diethylamino)phenol, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QSI
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BU of 5qsi by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z933326822
分子名称: 3-(benzyloxy)aniline, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献PanDDA analysis group deposition
To Be Published
4P2P
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BU of 4p2p by Molmil
AN INDEPENDENT CRYSTALLOGRAPHIC REFINEMENT OF PORCINE PHOSPHOLIPASE A2 AT 2.4 ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Finzel, B.C, Ohlendorf, D.H, Weber, P.C, Salemme, F.R.
登録日1991-10-22
公開日1992-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An independent crystallographic refinement of porcine phospholipase A2 at 2.4 A resolution
Acta Crystallogr.,Sect.B, 47, 1991
5QSB
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BU of 5qsb by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434874
分子名称: 1-{[4-(propan-2-yl)phenyl]methyl}piperidin-4-ol, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献PanDDA analysis group deposition
To Be Published
4A1X
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BU of 4a1x by Molmil
Co-Complex structure of NS3-4A protease with the inhibitory peptide CP5-46-A (Synchrotron data)
分子名称: CHLORIDE ION, CP5-46-A PEPTIDE, NONSTRUCTURAL PROTEIN 4A, ...
著者Schmelz, S, Kuegler, J, Collins, J, Heinz, D.
登録日2011-09-20
公開日2012-09-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants.
J.Biol.Chem., 287, 2012
5QSH
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BU of 5qsh by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434868
分子名称: 1-ethyl-N-(2-fluorophenyl)piperidin-4-amine, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5QT0
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BU of 5qt0 by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z321318226
分子名称: N-(4-methoxyphenyl)-N'-pyridin-4-ylurea, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-26
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献PanDDA analysis group deposition
To Be Published
6ZFD
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BU of 6zfd by Molmil
14-3-3 zeta bound to the phosphorylated 18E6 C-terminus
分子名称: 14-3-3 protein zeta/delta,Protein E6, GLYCEROL
著者Gogl, G, Tugaeva, K.V, Sluchanko, N.N, Trave, G.
登録日2020-06-17
公開日2021-02-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms.
Nat Commun, 12, 2021
5QSA
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BU of 5qsa by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434778
分子名称: 2-(trifluoromethoxy)benzoic acid, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献PanDDA analysis group deposition
To Be Published
6UHC
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BU of 6uhc by Molmil
CryoEM structure of human Arp2/3 complex with bound NPFs
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
著者Zimmet, A, van Eeuwen, T, Dominguez, R.
登録日2019-09-27
公開日2020-07-01
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.
Sci Adv, 6, 2020
4A1V
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BU of 4a1v by Molmil
Co-Complex structure of NS3-4A protease with the optimized inhibitory peptide CP5-46A-4D5E
分子名称: CHLORIDE ION, CP5-46A-4D5E, NON-STRUCTURAL PROTEIN 4A, ...
著者Schmelz, S, Kuegler, J, Collins, J, Heinz, D.W.
登録日2011-09-20
公開日2012-09-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants.
J.Biol.Chem., 287, 2012
6ZFG
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BU of 6zfg by Molmil
14-3-3 zeta chimera with 18E6 and fusicoccin
分子名称: 14-3-3 protein zeta/delta,Protein E6, FUSICOCCIN, GLYCEROL
著者Gogl, G, Tugaeva, K, Sluchanko, N.N, Trave, G.
登録日2020-06-17
公開日2021-02-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms.
Nat Commun, 12, 2021
5QSG
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BU of 5qsg by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434903
分子名称: N-[4-(4-methylpiperazin-1-yl)phenyl]acetamide, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献PanDDA analysis group deposition
To Be Published
6QHL
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BU of 6qhl by Molmil
14-3-3 sigma with RelA/p65 binding site pS45
分子名称: 14-3-3 protein sigma, GLYCEROL, Transcription factor p65
著者Wolter, M, Ottmann, C.
登録日2019-01-16
公開日2020-05-13
最終更新日2020-12-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products.
J.Am.Chem.Soc., 142, 2020
5QS8
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BU of 5qs8 by Molmil
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z1432018343
分子名称: (2S)-2-[(5-chloro-3-fluoropyridin-2-yl)amino]propan-1-ol, T-box transcription factor T
著者Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-05-25
公開日2019-08-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献PanDDA analysis group deposition
To Be Published
4ZLT
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BU of 4zlt by Molmil
Crystal structure of viral chemokine binding protein R17 in complex with CCL3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 3, Putative uncharacterized protein
著者Lubman, O.Y, Fremont, D.H.
登録日2015-05-01
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Structure, 24, 2016

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件を2024-08-07に公開中

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