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5BQD
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Crystal Structure of TBX5 (1-239) Dimer
分子名称: MAGNESIUM ION, T-box transcription factor TBX5
著者Pradhan, L, Gopal, S, Patel, A, Kasahara, H, Nam, H.J.
登録日2015-05-28
公開日2016-03-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.583 Å)
主引用文献Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.
Biochemistry, 55, 2016
4MVJ
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BU of 4mvj by Molmil
2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.
分子名称: ACETATE ION, ACETYLPHOSPHATE, CHLORIDE ION, ...
著者Minasov, G, Kuhn, M, Dubrovska, I, Winsor, J, Shuvalova, L, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-09-24
公開日2014-04-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.
Plos One, 9, 2014
1ZBA
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Foot-and-Mouth Disease virus serotype A1061 complexed with oligosaccharide receptor.
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Coat protein VP1, Coat protein VP2, ...
著者Fry, E.E, Newman, J.W, Curry, S, Najjam, S, Jackson, T, Blakemore, W, Lea, S.M, Miller, L, Burman, A, King, A.M, Stuart, D.I.
登録日2005-04-08
公開日2005-06-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Foot-and-mouth disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation.
J.Gen.Virol., 86, 2005
1ZBE
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Foot-and Mouth Disease Virus Serotype A1061
分子名称: Coat protein VP1, Coat protein VP2, Coat protein VP3, ...
著者Fry, E.E, Newman, J.W, Curry, S, Najjam, S, Jackson, T, Blakemore, W, Lea, S.M, Miller, L, Burman, A, King, A.M, Stuart, D.I.
登録日2005-04-08
公開日2005-06-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Foot-and-mouth disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation.
J.Gen.Virol., 86, 2005
3IIM
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The structure of hCINAP-dADP complex at 2.0 angstroms resolution
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Zographos, S.E, Drakou, C.E, Leonidas, D.D.
登録日2009-08-02
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies.
Proteins, 80, 2012
3QB7
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BU of 3qb7 by Molmil
Interleukin-4 mutant RGA bound to cytokine receptor common gamma
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ...
著者Bates, D.L, Junttila, I.S, Creusot, R.J, Moraga, I, Lupardus, P, Fathman, C.G, Paul, W.E, Garcia, K.C.
登録日2011-01-12
公開日2012-04-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.245 Å)
主引用文献Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines.
Nat.Chem.Biol., 8, 2012
2XYA
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Non-covalent inhibtors of rhinovirus 3C protease.
分子名称: 2-PHENYLQUINOLIN-4-OL, PICORNAIN 3C
著者Petersen, J, Edman, K, Edfeldt, F, Johansson, C.
登録日2010-11-16
公開日2011-04-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Non-Covalent Inhibitors of Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 21, 2011
3IIJ
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The structure of hCINAP-ADP complex at 1.76 angstroms resolution.
分子名称: ADENOSINE-5'-DIPHOSPHATE, Coilin-interacting nuclear ATPase protein, SULFATE ION
著者Zographos, S.E, Drakou, C.E, Leonidas, D.D.
登録日2009-08-02
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies.
Proteins, 80, 2012
3IIK
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The structure of hCINAP-SO4 complex at 1.95 angstroms resolution
分子名称: Coilin-interacting nuclear ATPase protein, SULFATE ION
著者Zographos, S.E, Drakou, C.E, Leonidas, D.D.
登録日2009-08-02
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies.
Proteins, 80, 2012
6VKQ
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Crystal Structure of human PARP-1 CAT domain bound to inhibitor EB-47
分子名称: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Poly [ADP-ribose] polymerase 1, SULFATE ION
著者Steffen, J.D, Pascal, J.M.
登録日2020-01-21
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
6VKK
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Crystal Structure of human PARP-1 CAT domain bound to inhibitor rucaparib
分子名称: GLYCEROL, Poly [ADP-ribose] polymerase 1, Rucaparib, ...
著者Steffen, J.D, Pascal, J.M.
登録日2020-01-21
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
1PIV
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BU of 1piv by Molmil
BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14
分子名称: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, MYRISTIC ACID, POLIOVIRUS TYPE 3 (SUBUNIT VP1), ...
著者Hiremath, C.N, Grant, R.A, Filman, D.J, Hogle, J.M.
登録日1995-02-02
公開日1995-06-03
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
Acta Crystallogr.,Sect.D, 51, 1995
3IIL
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BU of 3iil by Molmil
The structure of hCINAP-MgADP-Pi complex at 2.0 angstroms resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, Coilin-interacting nuclear ATPase protein, LITHIUM ION, ...
著者Zographos, S.E, Drakou, C.E, Leonidas, D.D.
登録日2009-08-02
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies.
Proteins, 80, 2012
6VKO
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BU of 6vko by Molmil
Crystal Structure of human PARP-1 CAT domain bound to inhibitor UKTT15
分子名称: Poly [ADP-ribose] polymerase 1, SULFATE ION, methyl 2-{4-[4-(7-carbamoyl-1H-benzimidazol-2-yl)benzene-1-carbonyl]piperazin-1-yl}pyrimidine-5-carboxylate
著者Langelier, M.F, Pascal, J.M.
登録日2020-01-21
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
3RI4
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BU of 3ri4 by Molmil
Ets1 cooperative binding to widely separated sites on promoter DNA
分子名称: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA
著者Babayeva, N.D, Mino, K, Tahirov, T.H.
登録日2011-04-12
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA.
Plos One, 7, 2012
1XO1
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T5 5'-EXONUCLEASE MUTANT K83A
分子名称: 5'-EXONUCLEASE
著者Ceska, T.A, Suck, D, Sayers, J.R.
登録日1998-11-19
公開日1999-04-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavage.
Proc.Natl.Acad.Sci.USA, 96, 1999
3QB1
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BU of 3qb1 by Molmil
Interleukin-2 mutant D10
分子名称: Interleukin-2
著者Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Fathman, C.G, Garcia, K.C.
登録日2011-01-12
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
3WE1
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BU of 3we1 by Molmil
Crystal structure of Dengue 4 Envelope protein domain III (ED3)
分子名称: Envelope protein E
著者Elahi, M, Islam, M.M, Noguchi, K, Yohda, M, Toh, H, Kuroda, Y.
登録日2013-06-27
公開日2014-01-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.278 Å)
主引用文献Computational prediction and experimental characterization of a "size switch type repacking" during the evolution of dengue envelope protein domain III (ED3).
Biochim.Biophys.Acta, 1844, 2014
2MXD
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BU of 2mxd by Molmil
Solution structure of VPg of porcine sapovirus
分子名称: Viral protein genome-linked
著者Kim, J, Hwang, H, Min, H, Yun, H, Cho, K, Pelton, J.G, Wemmer, D.E, Lee, C.
登録日2014-12-24
公開日2015-04-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the porcine sapovirus VPg core reveals a stable three-helical bundle with a conserved surface patch.
Biochem.Biophys.Res.Commun., 459, 2015
1SFK
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BU of 1sfk by Molmil
Core (C) protein from West Nile Virus, subtype Kunjin
分子名称: CALCIUM ION, CHLORIDE ION, Core protein, ...
著者Dokland, T, Walsh, M, Mackenzie, J.M, Khromykh, A.A, Ee, K.-H, Wang, S.
登録日2004-02-19
公開日2004-08-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献West nile virus core protein; tetramer structure and ribbon formation
Structure, 12, 2004
2HU2
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CTBP/BARS in ternary complex with NAD(H) and RRTGAPPAL peptide
分子名称: 9-mer peptide from Zinc finger protein 217, C-terminal-binding protein 1, FORMIC ACID, ...
著者Nardini, M, Bolognesi, M, Quinlan, K.G.R, Verger, A, Francescato, P, Crossley, M.
登録日2006-07-26
公開日2006-10-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins
Mol.Cell.Biol., 26, 2006
3JVK
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BU of 3jvk by Molmil
Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, histone H3.3 peptide
著者Vollmuth, F, Blankenfeldt, W, Geyer, M.
登録日2009-09-17
公開日2009-10-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
1KXA
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SINDBIS VIRUS CAPSID, (WILD-TYPE) RESIDUES 106-264, TETRAGONAL CRYSTAL FORM
分子名称: SINDBIS VIRUS CAPSID PROTEIN
著者Choi, H.-K, Rossmann, M.G.
登録日1996-05-05
公開日1996-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis.
J.Mol.Biol., 262, 1996
1F9L
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Solution Structure of a 22-Nucleotide Hairpin Similar to the P5ABC Region of a Group I Ribozyme with Cobalt(III)hexammine Complexed to the GAAA Tetraloop
分子名称: 5'-R(*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*AP*AP*AP*GP*AP*UP*GP*GP*CP*GP*CP*CP*)-3'
著者Rudisser, S, Tinoco Jr, I.
登録日2000-07-11
公開日2000-07-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Cobalt(III)hexammine complexed to the GAAA tetraloop, and metal-ion binding to G.A mismatches.
J.Mol.Biol., 295, 2000
1D4M
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THE CRYSTAL STRUCTURE OF COXSACKIEVIRUS A9 TO 2.9 A RESOLUTION
分子名称: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, MYRISTIC ACID, PROTEIN (COXSACKIEVIRUS A9)
著者Hendry, E, Hatanaka, H, Fry, E, Smyth, M, Tate, J, Stanway, G, Santti, J, Maaronen, M, Hyypia, T, Stuart, D.
登録日1999-10-04
公開日1999-12-23
最終更新日2023-05-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The crystal structure of coxsackievirus A9: new insights into the uncoating mechanisms of enteroviruses.
Structure Fold.Des., 7, 1999

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