PDB: 35439 件ウェブページステータス検索Chemie searchBIRD

---

5QQM	PanDDA analysis group deposition -- Crystal Structure of Kalirin/Rac1 in complex with MolPort-009-565-325 分子名称: 1,2-ETHANEDIOL, Kalirin, N-(1-benzyl-1H-pyrazol-4-yl)-N'-(5-methyl-1,2-oxazol-3-yl)urea, ... 著者 Gray, J.L, Krojer, T, Talon, R, Douangamath, A, Jimenez Antunez, C, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P.E, von Delft, F. 登録日 2019-05-03 公開日 2019-12-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QQF	PanDDA analysis group deposition -- Crystal Structure of Kalirin/Rac1 in complex with MolPort-004-412-710 分子名称: 1,2-ETHANEDIOL, Kalirin, N-ethyl-N'-1,3-thiazol-2-ylurea, ... 著者 Gray, J.L, Krojer, T, Talon, R, Douangamath, A, Jimenez Antunez, C, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P.E, von Delft, F. 登録日 2019-05-03 公開日 2019-12-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QQJ	PanDDA analysis group deposition -- Crystal Structure of Kalirin/Rac1 in complex with MolPort-009-587-558 分子名称: 1,2-ETHANEDIOL, Kalirin, N-{1-[(imidazo[1,2-a]pyridin-2-yl)methyl]-1H-pyrazol-4-yl}-N'-(5-methyl-1,2-oxazol-3-yl)urea, ... 著者 Gray, J.L, Krojer, T, Talon, R, Douangamath, A, Jimenez Antunez, C, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P.E, von Delft, F. 登録日 2019-05-03 公開日 2019-12-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QQL	PanDDA analysis group deposition -- Crystal Structure of Kalirin/Rac1 in complex with MolPort-009-565-301 分子名称: 1,2-ETHANEDIOL, Kalirin, N-(5-methyl-1,2-oxazol-3-yl)-N'-[2-(phenylsulfonyl)ethyl]urea, ... 著者 Gray, J.L, Krojer, T, Talon, R, Douangamath, A, Jimenez Antunez, C, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P.E, von Delft, F. 登録日 2019-05-03 公開日 2019-12-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5K5F	NMR structure of the HLTF HIRAN domain 分子名称: Helicase-like transcription factor 著者 Bezsonova, I, Neculai, D, Korzhnev, D, Weigelt, J, Bountra, C, Edwards, A, Arrowsmith, C, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2016-05-23 公開日 2016-06-08 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure of the HLTF HIRAN domain To Be Published
5QQH	PanDDA analysis group deposition -- Crystal Structure of Kalirin/Rac1 in complex with MolPort-020-096-465 分子名称: 1,2-ETHANEDIOL, Kalirin, N-methyl-5-({[(5-methyl-1,2-oxazol-3-yl)carbamoyl]amino}methyl)thiophene-2-sulfonamide, ... 著者 Gray, J.L, Krojer, T, Talon, R, Douangamath, A, Jimenez Antunez, C, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P.E, von Delft, F. 登録日 2019-05-03 公開日 2019-12-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QQI	PanDDA analysis group deposition -- Crystal Structure of Kalirin/Rac1 in complex with MolPort-009-178-994 分子名称: 1,2-ETHANEDIOL, Kalirin, N-[3-(methoxymethyl)phenyl]-N'-(5-methyl-1,2-oxazol-3-yl)urea, ... 著者 Gray, J.L, Krojer, T, Talon, R, Douangamath, A, Jimenez Antunez, C, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P.E, von Delft, F. 登録日 2019-05-03 公開日 2019-12-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QU9	PanDDA analysis group deposition of ground-state model of Kalirin/Rac1 screened against a customized urea fragment library by X-ray Crystallography at the XChem facility of Diamond Light Source beamline I04-1 分子名称: 1,2-ETHANEDIOL, Kalirin, Ras-related C3 botulinum toxin substrate 1 著者 Gray, J.L, Krojer, T, Talon, R, Douangamath, A, Jimenez Antunez, C, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P.E, von Delft, F. 登録日 2019-12-13 公開日 2020-01-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 PanDDA analysis group deposition of ground-state model To Be Published
5QQD	PanDDA analysis group deposition -- Crystal Structure of Kalirin/Rac1 in complex with Z56880342 分子名称: 1,2-ETHANEDIOL, Kalirin, N-ethyl-N'-(5-methyl-1,2-oxazol-3-yl)urea, ... 著者 Gray, J.L, Krojer, T, Talon, R, Douangamath, A, Jimenez Antunez, C, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P.E, von Delft, F. 登録日 2019-05-03 公開日 2019-12-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5L0C	Human metavinculin (residues 959-1134) in complex with PIP2 分子名称: PHOSPHATE ION, Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0F	Human metavinculin quadruple mutant (residues 959-1134) 分子名称: GLYCEROL, Vinculin 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5FEF	Crystal structure of the allergen profilin (Zea m 12) 分子名称: GLYCEROL, Profilin-5 著者 Mares-Mejia, I, Rodriguez-Romero, A. 登録日 2015-12-16 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms. Sci Rep, 6, 2016
5L0G	Human metavinculin MVt Q971R, R975D, T978R mutant (residues 959-1134) in complex with PIP2 分子名称: Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0D	Human Metavinculin(residues 959-1130) in complex with PIP2 分子名称: Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5L0H	Human metavinculin MVt cardiomyopathy-associated mutant R975W (residues 959-1134) in complex with PIP2 分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Vinculin, ... 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
6AJ4	Crystal structure of the DHR-2 domain of DOCK7 in complex with Cdc42 分子名称: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 著者 Kukimoto-Niino, M, Shirouzu, M. 登録日 2018-08-27 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.256 Å) 主引用文献 Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
6AJL	DOCK7 mutant I1836Y complexed with Cdc42 分子名称: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 著者 Kukimoto-Niino, M, Shirouzu, M. 登録日 2018-08-28 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
2K3T	Solution Structure of IG-Like Domain 23 from Human Filamin A 分子名称: Filamin-A 著者 Heikkinen, O.K, Ylanne, J, Kilpelainen, I, Kupiainen, O. 登録日 2008-05-16 公開日 2009-03-31 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Molecular basis of filamin A-FilGAP interaction and its impairment in congenital disorders associated with filamin A mutations Plos One, 4, 2009
1E96	Structure of the Rac/p67phox complex 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ... 著者 Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K. 登録日 2000-10-10 公開日 2000-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the TPR domain of p67phox in complex with Rac.GTP. Mol.Cell, 6, 2000
1T3X	Three Crystal Structures of Human Coactosin-like Protein 分子名称: Coactosin-like protein 著者 Liu, L, Wei, Z, Chen, Z, Wang, Y. 登録日 2004-04-28 公開日 2005-08-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Three Crystal Structures of Human Coactosin-like Protein TO BE PUBLISHED
1T3Y	Three Crystal Structures of Human Coactosin-like Protein 分子名称: Coactosin-like protein 著者 Liu, L, Wei, Z, Chen, Z, Wang, Y. 登録日 2004-04-28 公開日 2005-08-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Three Crystal Structures of Human Coactosin-like Protein To be Published
1FOE	CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1 分子名称: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE, SULFATE ION, T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1 著者 Worthylake, D.K, Rossman, K.L, Sondek, J. 登録日 2000-08-27 公開日 2001-01-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1. Nature, 408, 2000
4XSH	The complex structure of C3cer exoenzyme and GTP bound RhoA (NADH-bound state) 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... 著者 Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H. 登録日 2015-01-22 公開日 2015-06-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. J.Biol.Chem., 290, 2015
4XSG	The complex structure of C3cer exoenzyme and GTP bound RhoA (NADH-free state) 分子名称: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ADP-ribosyltransferase, ... 著者 Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H. 登録日 2015-01-22 公開日 2015-06-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. J.Biol.Chem., 290, 2015
4YKN	Pi3K alpha lipid kinase with Active Site Inhibitor 分子名称: 3-(6-methoxypyridin-3-yl)-5-[({4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}amino)methyl]benzoic acid, Phosphatidylinositol 3-kinase regulatory subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform fusion protein 著者 Elkins, P.A. 登録日 2015-03-04 公開日 2015-06-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery of a Potent Class of PI3K alpha Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT). Acs Med.Chem.Lett., 6, 2015

<264265266267268269270271272273274275276277278279>