4RVR
| Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801 | 分子名称: | 1,2-ETHANEDIOL, 1-{1-[2-(methylsulfonyl)phenyl]-7-propoxyindolizin-3-yl}ethanone, Bromodomain adjacent to zinc finger domain protein 2B | 著者 | Chaikuad, A, Felletar, I, Chung, C.W, Drewry, D, Chen, P, Filippakopoulos, P, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2014-11-27 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. J.Med.Chem., 59, 2016
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4R6D
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4NDK
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4NDJ
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4PPR
| Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein DacB1 | 著者 | Prigozhin, D.M, Huizar, J.P, Mavrici, D, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2014-02-27 | 公開日 | 2014-11-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis. Plos One, 9, 2014
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4WFD
| Structure of the Rrp6-Rrp47-Mtr4 interaction | 分子名称: | ATP-dependent RNA helicase DOB1, Exosome complex exonuclease RRP6, Exosome complex protein LRP1, ... | 著者 | Schuch, B, Conti, E. | 登録日 | 2014-09-14 | 公開日 | 2014-10-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase. Embo J., 33, 2014
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4WFC
| Structure of the Rrp6-Rrp47 interaction | 分子名称: | Exosome complex exonuclease RRP6, Exosome complex protein LRP1, SULFATE ION | 著者 | Schuch, B, Conti, E. | 登録日 | 2014-09-14 | 公開日 | 2014-10-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase. Embo J., 33, 2014
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4U2V
| Bak BH3-in-Groove dimer (GFP) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Green fluorescent protein,Bcl-2 homologous antagonist/killer | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2014-07-18 | 公開日 | 2014-09-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers. Mol.Cell, 55, 2014
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4N3D
| Crystal structure of the dimeric variant EGFP-K162Q in P61 space group | 分子名称: | GLYCEROL, Green fluorescent protein, PHOSPHATE ION, ... | 著者 | Pletneva, N.V, Pletnev, V.Z, Pletnev, S.V. | 登録日 | 2013-10-07 | 公開日 | 2014-08-27 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Three dimensional structure of the dimeric gene-engineered variant of green fluorescent protein egfp-K162Q in P61 crystal space group Rus.J.Bioorg.Chem., 40, 2014
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4U5T
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4KAG
| Crystal structure analysis of a single amino acid deletion mutation in EGFP | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ... | 著者 | Arpino, J.A.J, Rizkallah, P.J. | 登録日 | 2013-04-22 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein. Acta Crystallogr.,Sect.D, 70, 2014
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4KEX
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4TPS
| Sporulation Inhibitor of DNA Replication, SirA, in complex with Domain I of DnaA | 分子名称: | ACETATE ION, BETA-MERCAPTOETHANOL, Chromosomal replication initiator protein DnaA, ... | 著者 | Jameson, K.H, Turkenburg, J.P, Fogg, M.J, Grahl, A, Wilkinson, A.J. | 登録日 | 2014-06-09 | 公開日 | 2014-07-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure and interactions of the Bacillus subtilis sporulation inhibitor of DNA replication, SirA, with domain I of DnaA. Mol.Microbiol., 93, 2014
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4TS2
| Crystal structure of the Spinach RNA aptamer in complex with DFHBI, magnesium ions | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Warner, K.D, Chen, M.C, Song, W, Strack, R.L, Thorn, A, Jaffrey, S.R, Ferre-D'Amare, A.R. | 登録日 | 2014-06-18 | 公開日 | 2014-07-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.884 Å) | 主引用文献 | Structural basis for activity of highly efficient RNA mimics of green fluorescent protein. Nat.Struct.Mol.Biol., 21, 2014
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4TS0
| Crystal structure of the Spinach RNA aptamer in complex with DFHBI, barium ions | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, BARIUM ION, POTASSIUM ION, ... | 著者 | Warner, K.D, Chen, M.C, Song, W, Strack, R.L, Thorn, A, Jaffrey, S.R, Ferre-D'Amare, A.R. | 登録日 | 2014-06-18 | 公開日 | 2014-07-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for activity of highly efficient RNA mimics of green fluorescent protein. Nat.Struct.Mol.Biol., 21, 2014
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4P1Q
| GREEN FLUORESCENT PROTEIN E222H VARIANT | 分子名称: | Green fluorescent protein, SODIUM ION | 著者 | Klein, M, Carius, Y, Auerbach, D, Franz, S, Jung, G, Lancaster, C.R.D. | 登録日 | 2014-02-27 | 公開日 | 2014-07-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Replacement of Highly Conserved E222 by the Photostable Non-photoconvertible Histidine in GFP. Chembiochem, 15, 2014
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4PQI
| Crystal structure of glutathione transferase lambda3 from Populus trichocarpa | 分子名称: | CALCIUM ION, GLUTATHIONE, In2-1 family protein, ... | 著者 | Lallement, P.A, Meux, E, Gualberto, J.M, Prosper, P, Didierjean, C, Haouz, A, Saul, F, Rouhier, N, Hecker, A. | 登録日 | 2014-03-03 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and enzymatic insights into Lambda glutathione transferases from Populus trichocarpa, monomeric enzymes constituting an early divergent class specific to terrestrial plants. Biochem.J., 462, 2014
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4PQH
| Crystal structure of glutathione transferase lambda1 from Populus trichocarpa | 分子名称: | GLUTATHIONE, SODIUM ION, glutathione transferase lambda1 | 著者 | Lallement, P.A, Meux, E, Gualberto, J.M, Prosper, P, Didierjean, C, Haouz, A, Saul, F, Rouhier, N, Hecker, A. | 登録日 | 2014-03-03 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural and enzymatic insights into Lambda glutathione transferases from Populus trichocarpa, monomeric enzymes constituting an early divergent class specific to terrestrial plants. Biochem.J., 462, 2014
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4Q9Q
| Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab | 分子名称: | (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | 著者 | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | 登録日 | 2014-05-01 | 公開日 | 2014-06-18 | 最終更新日 | 2017-07-26 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4Q9R
| Crystal structure of an RNA aptamer bound to trifluoroethyl-ligand analog in complex with Fab | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | 著者 | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | 登録日 | 2014-05-01 | 公開日 | 2014-06-18 | 最終更新日 | 2017-07-26 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4KZD
| Crystal structure of an RNA aptamer in complex with fluorophore and Fab | 分子名称: | 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ... | 著者 | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | 登録日 | 2013-05-29 | 公開日 | 2014-06-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.186 Å) | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4KZE
| Crystal structure of an RNA aptamer in complex with Fab | 分子名称: | BL3-6 Fab antibody, heavy chain, light chain, ... | 著者 | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | 登録日 | 2013-05-29 | 公開日 | 2014-06-18 | 最終更新日 | 2014-07-30 | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4CQH
| Structure of Infrared Fluorescent Protein IFP2.0 | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, BACTERIOPHYTOCHROME, SODIUM ION | 著者 | Lafaye, C, Yu, D, Noirclerc-Savoye, M, Shu, X, Royant, A. | 登録日 | 2014-02-17 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | An Improved Monomeric Infrared Fluorescent Protein for Neuronal and Tumour Brain Imaging. Nat.Commun., 5, 2014
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4P7H
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4Q9W
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