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2JY7
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BU of 2jy7 by Molmil
NMR structure of the ubiquitin associated (UBA) domain of p62 (SQSTM1). RDC refined
分子名称: Ubiquitin-binding protein p62
著者Long, J.E, Layfield, R, Searle, M.S.
登録日2007-12-07
公開日2007-12-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Ubiquitin Recognition by the Ubiquitin-associated Domain of p62 Involves a Novel Conformational Switch
J.Biol.Chem., 283, 2008
2K07
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BU of 2k07 by Molmil
Solution NMR structure of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1). Northeast Structural Genomics Consortium target HR41
分子名称: Ufm1-conjugating enzyme 1
著者Liu, G, Eletsky, A, Atreya, H.S, Aramini, J.M, Xiao, R, Acton, T, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2008-01-25
公開日2008-02-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway.
J.STRUCT.FUNCT.GENOM., 10, 2009
2JHL
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BU of 2jhl by Molmil
Structure of globular heads of M-ficolin complexed with sialic acid
分子名称: CALCIUM ION, FICOLIN-1, N-acetyl-beta-neuraminic acid
著者Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C.
登録日2007-02-22
公開日2007-10-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
J.Biol.Chem., 282, 2007
2JUL
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BU of 2jul by Molmil
NMR Structure of DREAM
分子名称: CALCIUM ION, Calsenilin
著者Ames, J.
登録日2007-08-30
公開日2008-04-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR structure of DREAM: Implications for Ca(2+)-dependent DNA binding and protein dimerization.
Biochemistry, 47, 2008
2JW5
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BU of 2jw5 by Molmil
Polymerase Lambda BRCT domain
分子名称: DNA polymerase lambda
著者Mueller, G.A, Moon, A.F, DeRose, E.F, Pedersen, L.C, London, R.E.
登録日2007-10-05
公開日2007-10-23
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Polymerase Lambda BRCT domain
To be Published
2JYU
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BU of 2jyu by Molmil
Human Granulin C, isomer 2
分子名称: Granulin-5
著者Tolkatchev, D, Wang, P, Chen, Z, Xu, P, Ni, F.
登録日2007-12-19
公開日2008-04-22
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities.
Protein Sci., 17, 2008
2K40
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BU of 2k40 by Molmil
NMR structure of HESX-1 homeodomain double mutant R31L/E42L
分子名称: Homeobox expressed in ES cells 1
著者Asensio, J, Torrado, M, Gonzalez, C, Bastida, A.
登録日2008-05-26
公開日2009-05-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The role of conserved salt-bridges on homeodomain stability
To be Published
2K4A
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BU of 2k4a by Molmil
FGF-1-C2A binary complex structure: a key component in the fibroblast growthfactor non-classical pathway
分子名称: Heparin-binding growth factor 1, Synaptotagmin-1
著者Yu, C, Mohan, S.K.
登録日2008-06-02
公開日2009-06-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release
To be Published
2JK7
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BU of 2jk7 by Molmil
XIAP BIR3 bound to a Smac Mimetic
分子名称: (3S,6S,7Z,10AS)-N-(DIPHENYLMETHYL)-6-{[(2S)-2-(METHYLIDENEAMINO)BUTANOYL]AMINO}-5-OXO-1,2,3,5,6,9,10,10A-OCTAHYDROPYRROLO[1,2-A]AZOCINE-3-CARBOXAMIDE, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, ZINC ION
著者Saito, N.G, Meagher, J.L, Stuckey, J.A.
登録日2008-08-21
公開日2008-11-04
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (Xiap).
J.Med.Chem., 51, 2008
2K3G
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BU of 2k3g by Molmil
NMR structure analysis of a BMP receptor
分子名称: Bone morphogenetic protein receptor type-1A
著者Klages, J, Kotzsch, A, Mueller, T, Kessler, H.
登録日2008-05-07
公開日2008-12-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding.
Biochemistry, 47, 2008
2JT0
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BU of 2jt0 by Molmil
Solution structure of F104W cardiac troponin C
分子名称: Troponin C, slow skeletal and cardiac muscles
著者Wang, X, Mercier, P, Letourneau, P.-J, Sykes, B.D.
登録日2007-07-17
公開日2008-05-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies.
Protein Sci., 14, 2005
2JW2
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BU of 2jw2 by Molmil
Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
分子名称: StAR-related lipid transfer protein 13
著者Li, H, Sze, K, Fung, K.
登録日2007-10-03
公開日2008-10-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
To be Published
2JXO
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BU of 2jxo by Molmil
Structure of the second PDZ domain of NHERF-1
分子名称: Ezrin-radixin-moesin-binding phosphoprotein 50
著者Cheng, H, Li, J, Dai, Z, Bu, Z, Roder, H.
登録日2007-11-27
公開日2008-12-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Autoinhibitory Interactions between the PDZ2 and C-terminal Domains in the Scaffolding Protein NHERF1
Structure, 17, 2009
2L1D
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BU of 2l1d by Molmil
Mouse prion protein (121-231) containing the substitution Y169G
分子名称: Major prion protein
著者Christen, B, Damberger, F.F, Perez, D.R, Hornemann, S, Wuthrich, K.
登録日2010-07-28
公開日2011-08-10
最終更新日2011-11-09
実験手法SOLUTION NMR
主引用文献Cellular prion protein conformation and function.
Proc.Natl.Acad.Sci.USA, 108, 2011
2LAI
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BU of 2lai by Molmil
Hyaloperonospora arabidopsidis Effector Protein ATR13
分子名称: Avirulence protein ATR13
著者Leonelli, L, Pelton, J.G, Wemmer, D.E, Staskawicz, B.J.
登録日2011-03-15
公開日2012-01-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Elucidation and Functional Characterization of the Hyaloperonospora arabidopsidis Effector Protein ATR13.
Plos Pathog., 7, 2011
3I7O
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BU of 3i7o by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of IQWD1
分子名称: DNA damage-binding protein 1, IQ motif and WD repeat-containing protein 1
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3IC2
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BU of 3ic2 by Molmil
Crystal Structure of liganded hemoglobin in complex with a potent antisickling agent, INN-266
分子名称: 4-[(5-methoxy-2-methylphenoxy)methyl]pyridine, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Safo, M.K, Musayev, F.N, Gandhi, A.K, Jorge, P.
登録日2009-07-17
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and in Vitro Chracterization of Pyridyl Derivatives of Benzaldehydes: Highly Potent Antisickling Agents
To be Published
3I97
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BU of 3i97 by Molmil
B1 domain of human Neuropilin-1 bound with small molecule EG00229
分子名称: (S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)thiophene-2-carboxamido)-5-guanidinopentanoic acid, GLYCEROL, Neuropilin-1
著者Allerston, C.K, Djordjevic, S.
登録日2009-07-10
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.
J.Med.Chem., 53, 2010
3IF8
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BU of 3if8 by Molmil
Crystal Structure of ZWILCH, a member of the RZZ kinetochore complex
分子名称: Protein zwilch homolog
著者Wehenkel, A, Civril, F, Musacchio, A.
登録日2009-07-24
公開日2010-06-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery.
Structure, 18, 2010
3IGP
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BU of 3igp by Molmil
Structure of inhibitor binding to Carbonic Anhydrase II
分子名称: 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
著者Gitto, R, Agnello, S, Brynda, J, Mader, P, Supuran, C.T, Chimirri, A.
登録日2009-07-28
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme-Ligand X-ray Studies.
J.Med.Chem., 2010
3II5
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BU of 3ii5 by Molmil
The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor
分子名称: B-Raf proto-oncogene serine/threonine-protein kinase, N-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide, PHOSPHATE ION
著者Xu, W, Breger, D, Torres, N, Dutia, M, Powell, D, Ciszewski, G.
登録日2009-07-31
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
3IFQ
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BU of 3ifq by Molmil
Interction of plakoglobin and beta-catenin with desmosomal cadherins
分子名称: E-cadherin, SULFATE ION, plakoglobin
著者Choi, H.-J, Gross, J.C, Pokutta, S, Weis, W.I.
登録日2009-07-24
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
J.Biol.Chem., 284, 2009
3DE6
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BU of 3de6 by Molmil
Proteinase K by Classical hanging drop method after the third step of high X-Ray dose on ESRF ID23-1 beamline
分子名称: CALCIUM ION, Proteinase K
著者Pechkova, E, Tripathi, S.K, Nicolini, C.
登録日2008-06-08
公開日2009-06-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Radiation stability of proteinase K crystals grown by LB nanotemplate method
J.Struct.Biol., 168, 2009
2RB8
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High resolution design of a protein loop
分子名称: Tenascin
著者Hu, X, Wang, H, Ke, H, Kuhlman, B.
登録日2007-09-18
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献High-resolution design of a protein loop.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3IMW
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BU of 3imw by Molmil
Transthyretin in complex with (E)-2,6-dibromo-4-(2,6-dimethoxystyryl)aniline
分子名称: 2,6-dibromo-4-[(E)-2-(2,6-dimethoxyphenyl)ethenyl]aniline, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010

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