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1NHA
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Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP-Binding Sites of RAP74 and CTD of RAP74, the subunit of Human TFIIF
分子名称: Transcription initiation factor IIF, alpha subunit
著者Nguyen, B.D, Chen, H.T, Kobor, M.S, Greenblatt, J, Legault, P, Omichinski, J.G.
登録日2002-12-19
公開日2003-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP1-Binding Sites of RAP74 and Human TFIIB.
Biochemistry, 42, 2003
3BEP
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BU of 3bep by Molmil
Structure of a sliding clamp on DNA
分子名称: 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ...
著者Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M.
登録日2007-11-19
公開日2008-01-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure of a sliding clamp on DNA
Cell(Cambridge,Mass.), 132, 2008
1NG0
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The three-dimensional structure of Cocksfoot mottle virus at 2.7A resolution
分子名称: CALCIUM ION, coat protein
著者Tars, K, Zeltins, A, Liljas, L.
登録日2002-12-16
公開日2003-02-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The three-dimensional structure of cocksfoot mottle virus at 2.7 A resolution.
Virology, 310, 2003
6VCD
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BU of 6vcd by Molmil
Cryo-EM structure of IRP2-FBXL5-SKP1 complex
分子名称: F-box/LRR-repeat protein 5, FE2/S2 (INORGANIC) CLUSTER, Iron-responsive element binding protein 2, ...
著者Wang, H, Shi, H, Zheng, N.
登録日2019-12-20
公開日2020-08-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster.
Mol.Cell, 78, 2020
6W4S
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BU of 6w4s by Molmil
Structure of apo human ferroportin in lipid nanodisc
分子名称: Fab45D8 Heavy Chain, Fab45D8 Light Chain, Solute carrier family 40 member 1
著者Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A.
登録日2020-03-11
公開日2020-09-09
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
1TIV
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BU of 1tiv by Molmil
STRUCTURAL STUDIES OF HIV-1 TAT PROTEIN
分子名称: HIV-1 TRANSACTIVATOR PROTEIN
著者Bayer, P, Kraft, M, Frank, R, Roesch, P.
登録日1995-02-14
公開日1995-07-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural studies of HIV-1 Tat protein.
J.Mol.Biol., 247, 1995
1ROQ
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BU of 1roq by Molmil
Extending the Family of UNCG-like Tetraloop Motifs: NMR Structure of a CACG Tetraloop from Coxsackievirus B3
分子名称: 5'-R(*GP*GP*UP*AP*UP*CP*AP*CP*GP*GP*UP*AP*CP*C)-3'
著者Du, Z, Yu, J, Andino, R, James, T.L.
登録日2003-12-02
公開日2004-05-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Extending the Family of UNCG-like Tetraloop Motifs: NMR Structure of a CACG Tetraloop from Coxsackievirus B3
Biochemistry, 42, 2003
4DG2
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Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20
分子名称: MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
著者Bastidas, A.C, Steichen, J.M, Taylor, S.S.
登録日2012-01-24
公開日2012-06-06
最終更新日2013-01-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
4DFX
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Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP
分子名称: GLYCEROL, MAGNESIUM ION, MYRISTIC ACID, ...
著者Bastidas, A.C, Steichen, J.M, Taylor, S.S.
登録日2012-01-24
公開日2012-06-06
最終更新日2013-01-02
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
8T2S
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BU of 8t2s by Molmil
Structure of a group II intron ribonucleoprotein in the pre-branching (pre-1F) state
分子名称: AMMONIUM ION, CALCIUM ION, Group II intron reverse transcriptase/maturase, ...
著者Xu, L, Liu, T, Chung, K, Pyle, A.M.
登録日2023-06-06
公開日2023-11-22
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
4DFZ
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Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20
分子名称: MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
著者Bastidas, A.C, Steichen, J.M, Taylor, S.S.
登録日2012-01-24
公開日2012-06-06
最終更新日2013-01-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
5FX5
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BU of 5fx5 by Molmil
Novel inhibitors of human rhinovirus 3C protease
分子名称: GLYCEROL, RHINOVIRUS 3C PROTEASE, TETRAETHYLENE GLYCOL, ...
著者Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q.
登録日2016-02-24
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
4DG0
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BU of 4dg0 by Molmil
Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP
分子名称: MAGNESIUM ION, MYRISTIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Bastidas, A.C, Steichen, J.M, Taylor, S.S.
登録日2012-01-24
公開日2012-06-06
最終更新日2013-01-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
5FX6
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BU of 5fx6 by Molmil
Novel inhibitors of human rhinovirus 3C protease
分子名称: RHINOVIRUS 3C PROTEASE, ethyl (4R)-4-[[(2S,4S)-1-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)carbonylamino]butanoyl]-4-phenyl-pyrrolidin-2-yl]carbonylamino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate
著者Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q.
登録日2016-02-24
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
2BHG
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BU of 2bhg by Molmil
3C protease from type A10(61) foot-and-mouth disease virus
分子名称: FOOT-AND-MOUTH DISEASE VIRUS 3C PROTEASE
著者Birtley, J.R, Brick, P, Curry, S.
登録日2005-01-10
公開日2005-02-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease: New Insights Into Catalytic Mechanism and Cleavage Specificity
J.Biol.Chem., 280, 2005
1ZH1
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BU of 1zh1 by Molmil
Structure of the zinc-binding domain of HCV NS5A
分子名称: ZINC ION, non-structural polyprotein
著者Tellinghuisen, T.L, Marcotrigiano, J, Rice, C.M.
登録日2005-04-22
公開日2005-05-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase.
Nature, 435, 2005
4ZZZ
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BU of 4zzz by Molmil
Structure of human PARP1 catalytic domain bound to an isoindolinone inhibitor
分子名称: 2-(3-methoxypropyl)-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide, GLYCEROL, POLY [ADP-RIBOSE] POLYMERASE 1, ...
著者Casale, E, Fasolini, M, Papeo, G, Posteri, H, Borghi, D, Busel, A.A, Caprera, F, Ciomei, M, Cirla, A, Corti, E, DAnello, M, Fasolini, M, Felder, E.R, Forte, B, Galvani, A, Isacchi, A, Khvat, A, Krasavin, M.Y, Lupi, R, Orsini, P, Perego, R, Pesenti, E, Pezzetta, D, Rainoldi, S, RiccardiSirtori, F, Scolaro, A, Sola, F, Zuccotto, F, Donati, D, Montagnoli, A.
登録日2015-04-15
公開日2015-08-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of 2-[1-(4,4-Difluorocyclohexyl)Piperidin-4-Yl]-6-Fluoro-3-Oxo-2,3-Dihydro-1H-Isoindole-4-Carboxamide (Nms-P118): A Potent, Orally Available and Highly Selective Parp- 1 Inhibitor for Cancer Therapy.
J.Med.Chem., 58, 2015
1S9S
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BU of 1s9s by Molmil
SOLUTION STRUCTURE OF MLV PSI SITE
分子名称: MLV Psi encapsidation site
著者D'Souza, V, Dey, A, Habib, D, Summers, M.F.
登録日2004-02-05
公開日2004-04-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the 101-nucleotide core encapsidation signal of the Moloney Murine Leukemia Virus.
J.Mol.Biol., 337, 2004
4QJH
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BU of 4qjh by Molmil
Crystal Structure of the Twister Ribozyme with the Nucleotide 5'- to the Cleavage Site Ordered at 4.1 A Resolution
分子名称: MAGNESIUM ION, Twister Ribozyme
著者Eiler, D.R, Wang, J, Steitz, T.A.
登録日2014-06-03
公開日2014-09-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.88 Å)
主引用文献Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
7KSE
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BU of 7kse by Molmil
Crystal structure of Prototype Foamy Virus Protease-Reverse Transcriptase CSH mutant (selenomethionine-labeled)
分子名称: CALCIUM ION, Peptidase A9/Reverse transcriptase/RNase H
著者Harrison, J.J.E.K, Das, K, Ruiz, F.X, Arnold, E.
登録日2020-11-21
公開日2021-08-11
最終更新日2021-09-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT).
Viruses, 13, 2021
3FJ9
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Crystal structure of F85W mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3FJB
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Crystal structure of V31I mutant of Human acidic fibroblast growth factor
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
2WV9
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Crystal Structure of the NS3 protease-helicase from Murray Valley encephalitis virus
分子名称: FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT, FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT
著者Assenberg, R, Mastrangelo, E, Walter, T.S, Verma, A, Milani, M, Owens, R.J, Stuart, D.I, Grimes, J.M, Mancini, E.J.
登録日2009-10-15
公開日2009-12-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal Structure of a Novel Conformational State of the Flavivirus Ns3 Protein: Implications for Polyprotein Processing and Viral Replication.
J.Virol., 83, 2009
5NAN
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Crystal Structure of human IL-17AF in complex with human IL-17RA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-galactopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Rondeau, J.-M, Goepfert, A.
登録日2017-02-28
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties.
Sci Rep, 7, 2017
5N92
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Crystal Structure of Human IL-17AF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17A, Interleukin-17F
著者Rondeau, J.-M, Goepfert, A.
登録日2017-02-24
公開日2017-09-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties.
Sci Rep, 7, 2017

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