4UPN
 
 | | Structure of rat neuronal nitric oxide synthase heme domain in complex with N,N''-{[(2S)-3-aminopropane-1,2-diyl]bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximidamide | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N,N''-{[(2S)-3-aminopropane-1,2-diyl]bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximidamide, ... | | 著者 | Li, H, Poulos, T.L. | | 登録日 | 2014-06-17 | | 公開日 | 2014-08-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Combination of Chiral Linkers with Thiophenecarboximidamide Heads to Improve the Selectivity of Inhibitors of Neuronal Nitric Oxide Synthase.
Bioorg.Med.Chem.Lett., 24, 2014
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1XUT
 | | Solution structure of TACI-CRD2 | | 分子名称: | Tumor necrosis factor receptor superfamily member 13B | | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | | 登録日 | 2004-10-26 | | 公開日 | 2004-11-09 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding.
J.Biol.Chem., 280, 2005
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7ORB
 | | Crystal structure of the L452R mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-75 and COVOX-253 Fabs | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhou, D, Ren, J, Stuart, D.I. | | 登録日 | 2021-06-04 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum.
Cell, 184, 2021
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1YZL
 | | GppNHp-Bound Rab9 GTPase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-9A | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-02-28 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z0I
 | | GDP-Bound Rab21 GTPase | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-21 | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-01 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z0F
 | | GDP-Bound Rab14 GTPase | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAB14, ... | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-01 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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8HTU
 | | Cryo-EM structure of PpPSI-L | | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | 著者 | Li, M, Pan, X.W, Sun, H.Y. | | 登録日 | 2022-12-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Structural insights into the assembly and energy transfer of the Lhcb9-dependent photosystem I from moss Physcomitrium patens.
Nat.Plants, 9, 2023
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1Z2A
 | | GDP-Bound Rab23 GTPase crystallized in P2(1)2(1)2(1) space group | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-23 | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-07 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1XU1
 | | The crystal structure of APRIL bound to TACI | | 分子名称: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 13B | | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | | 登録日 | 2004-10-25 | | 公開日 | 2004-11-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
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1XUX
 | | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogs | | 分子名称: | DNA (5'-D(*GP*CP*GP*TP*AP*(NMS)P*AP*CP*GP*C)-3') | | 著者 | Pattanayek, R, Sethaphong, L, Pan, C, Prhavc, M, Prakash, T.P, Manoharan, M, Egli, M. | | 登録日 | 2004-10-26 | | 公開日 | 2004-12-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.
J.Am.Chem.Soc., 126, 2004
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1XU2
 | | The crystal structure of APRIL bound to BCMA | | 分子名称: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 17 | | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | | 登録日 | 2004-10-25 | | 公開日 | 2004-11-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
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1XT9
 | | Crystal Structure of Den1 in complex with Nedd8 | | 分子名称: | Neddylin, Sentrin-specific protease 8 | | 著者 | Reverter, D, Wu, K, Erdene, T.G, Pan, Z.Q, Wilkinson, K.D, Lima, C.D. | | 登録日 | 2004-10-21 | | 公開日 | 2004-12-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a Complex between Nedd8 and the Ulp/Senp Protease Family Member Den1.
J.Mol.Biol., 345, 2005
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1YVD
 | | GppNHp-Bound Rab22 GTPase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-22A | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-02-15 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1YZT
 | | GppNHp-Bound Rab21 GTPase at 2.05 A Resolution | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-21 | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-02-28 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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6WTT
 | | Crystals Structure of the SARS-CoV-2 (COVID-19) main protease with inhibitor GC-376 | | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ... | | 著者 | Sacco, M, Ma, C, Chen, Y, Wang, J. | | 登録日 | 2020-05-03 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
Cell Res., 30, 2020
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1Z0K
 | | Structure of GTP-Bound Rab4Q67L GTPase in complex with the central Rab binding domain of Rabenosyn-5 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FYVE-finger-containing Rab5 effector protein rabenosyn-5, GTP-binding protein, ... | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-01 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1Z22
 | | GDP-Bound Rab23 GTPase crystallized in C222(1) space group | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-23 | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-07 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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2A2E
 | | Crystal structure of the RNA subunit of Ribonuclease P. Bacterial A-type. | | 分子名称: | OSMIUM ION, RNA subunit of RNase P | | 著者 | Torres-Larios, A, Swinger, K.K, Krasilnikov, A.S, Pan, T, Mondragon, A. | | 登録日 | 2005-06-22 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | Crystal structure of the RNA component of bacterial ribonuclease P.
Nature, 437, 2005
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1YU9
 | | GppNHp-Bound Rab4A | | 分子名称: | GTP-binding protein, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-02-13 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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1XUW
 | | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogs | | 分子名称: | DNA (5'-D(*GP*CP*GP*TP*AP*(NMT)P*AP*CP*GP*C)-3') | | 著者 | Pattanayek, R, Sethaphong, L, Pan, C, Prhavc, M, Prakash, T.P, Manoharan, M, Egli, M. | | 登録日 | 2004-10-26 | | 公開日 | 2004-12-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.
J.Am.Chem.Soc., 126, 2004
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2ZNQ
 | | Human PPAR delta ligand binding domain in complex with a synthetic agonist TIPP401 | | 分子名称: | (2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid, Peroxisome proliferator-activated receptor delta, heptyl beta-D-glucopyranoside | | 著者 | Oyama, T, Hirakawa, Y, Nagasawa, N, Miyachi, H, Morikawa, K. | | 登録日 | 2008-04-30 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures
Acta Crystallogr.,Sect.D, 65, 2009
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2ZNP
 | | Human PPAR delta ligand binding domain in complex with a synthetic agonist TIPP204 | | 分子名称: | (2S)-2-{4-butoxy-3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]benzyl}butanoic acid, Peroxisome proliferator-activated receptor delta, heptyl beta-D-glucopyranoside | | 著者 | Oyama, T, Hirakawa, Y, Nagasawa, N, Miyachi, H, Morikawa, K. | | 登録日 | 2008-04-30 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures
Acta Crystallogr.,Sect.D, 65, 2009
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1Z07
 | | GppNHp-Bound Rab5c G55Q mutant GTPase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-5C | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-01 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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5X0W
 | | Molecular mechanism for the binding between Sharpin and HOIP | | 分子名称: | E3 ubiquitin-protein ligase RNF31, Sharpin | | 著者 | Liu, J, Li, F, Cheng, X, Pan, L. | | 登録日 | 2017-01-23 | | 公開日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Cell Rep, 21, 2017
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1YZK
 | | GppNHp bound Rab11 GTPase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-11A | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-02-28 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
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