PDB: 245663 件ウェブページステータス検索Chemie searchBIRD

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3OGQ	Crystal Structure of 6s-98S FIV Protease with Lopinavir bound 分子名称: DIMETHYL SULFOXIDE, FIV protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE 著者 Lin, Y.-C, Perryman, A.L, Elder, J.H, Stout, C.D. 登録日 2010-08-17 公開日 2011-06-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease. Acta Crystallogr.,Sect.D, 67, 2011
1Z7C	Crystal Structure of Human Placental Lactogen 分子名称: Chorionic somatomammotropin hormone 著者 Walsh, S.T.R, Kossiakoff, A.A. 登録日 2005-03-24 公開日 2006-03-07 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure and Site 1 Binding Energetics of Human Placental Lactogen. J.Mol.Biol., 358, 2006
1AZM	DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE I, ZINC ION 著者 Chakravarty, S, Kannan, K.K. 登録日 1993-11-28 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme. J.Mol.Biol., 243, 1994
4HZ0	Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. 分子名称: 7-(1H-imidazol-1-yl)-2-(pyridin-3-yl)[1,3]thiazolo[5,4-d]pyrimidin-5-amine, DNA topoisomerase 4 subunit B, MAGNESIUM ION 著者 Bensen, D.C, Trzoss, M, Tari, L.W. 登録日 2012-11-14 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. Bioorg.Med.Chem.Lett., 23, 2013
1IN4	THERMOTOGA MARITIMA RUVB HOLLIDAY JUNCTION BRANCH MIGRATION MOTOR 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ... 著者 Putnam, C.D, Tainer, J.A. 登録日 2001-05-12 公開日 2001-08-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure and mechanism of the RuvB Holliday junction branch migration motor. J.Mol.Biol., 311, 2001
1U7C	Crystal Structure of AmtB from E.Coli with Methyl Ammonium. 分子名称: METHYLAMINE, Probable ammonium transporter 著者 Khademi, S, O'Connell III, J, Remis, J, Robles-Colmenares, Y, Miercke, L.J.W, Stroud, R.M. 登録日 2004-08-03 公開日 2004-09-21 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A Science, 305, 2004
3CGX	Crystal structure of putative nucleotide-diphospho-sugar transferase (YP_389115.1) from Desulfovibrio desulfuricans G20 at 1.90 A resolution 分子名称: IMIDAZOLE, Putative nucleotide-diphospho-sugar transferase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2008-03-06 公開日 2008-03-18 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of putative Nucleotide-diphospho-sugar Transferase (YP_389115.1) from Desulfovibrio desulfuricans G20 at 1.90 A resolution To be published
4HXF	Acylaminoacyl peptidase in complex with Z-Gly-Gly-Phe-chloromethyl ketone 分子名称: CHLORIDE ION, HEXANE-1,6-DIOL, MAGNESIUM ION, ... 著者 Kiss-Szeman, A, Menyhard, D.K, Tichy-Racs, E, Hornung, B, Radi, K, Szeltner, Z, Domokos, K, Szamosi, I, Naray-Szabo, G, Polgar, L, Harmat, V. 登録日 2012-11-09 公開日 2013-05-08 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION. J.Biol.Chem., 288, 2013
6M4Y	Structure of a R371A mutant of a Group II PLP dependent decarboxylase from Methanocaldococcus jannaschii 分子名称: GLYCEROL, L-tyrosine/L-aspartate decarboxylase, SULFATE ION 著者 Manoj, N, Chellam Gayathri, S. 登録日 2020-03-09 公開日 2020-12-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic Snapshots of the Dunathan and Quinonoid Intermediates provide Insights into the Reaction Mechanism of Group II Decarboxylases. J.Mol.Biol., 432, 2020
2QXF	Product bound structure of exonuclease I at 1.5 angstrom resolution 分子名称: Exodeoxyribonuclease I, MAGNESIUM ION, SODIUM ION, ... 著者 Busam, R.D. 登録日 2007-08-11 公開日 2008-01-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of Escherichia coli exonuclease I in complex with thymidine 5'-monophosphate. Acta Crystallogr.,Sect.D, 64, 2008
2MHG	NMR structure of protein NP_254181.1 from Pseudomonas aeruginosa PA01 分子名称: Uncharacterized protein 著者 Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG) 登録日 2013-11-22 公開日 2014-01-01 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure of protein NP_254181.1 from Pseudomonas aeruginosa PA01 To be Published
2ZBD	Crystal Structure of the SR Calcium Pump with Bound Aluminium Fluoride, ADP and Calcium 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... 著者 Toyoshima, C, Nomura, H, Tsuda, T, Ogawa, H, Norimatsu, Y. 登録日 2007-10-20 公開日 2007-11-20 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues Nature, 432, 2004
4I73	Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 分子名称: (2R,3R,4S)-2-(hydroxymethyl)-1-[(4-hydroxythieno[3,2-d]pyrimidin-7-yl)methyl]pyrrolidine-3,4-diol, CALCIUM ION, Inosine-adenosine-guanosine-nucleoside hydrolase, ... 著者 Giannese, F, Degano, M. 登録日 2012-11-30 公開日 2013-08-07 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor Acta Crystallogr.,Sect.D, 69, 2013
4I71	Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with a trypanocidal compound 分子名称: (2R,3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-2-(hydroxymethyl)pyrrolidine-3,4-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... 著者 Giannese, F, Degano, M. 登録日 2012-11-30 公開日 2013-08-07 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor Acta Crystallogr.,Sect.D, 69, 2013
3OF9	Structural Basis for Irreversible Inhibition of Human Cathepsin L by a Diazomethylketone Inhibitor 分子名称: Cathepsin L1, Nalpha-[(benzyloxy)carbonyl]-N-[(1S)-1-(4-tert-butoxybenzyl)-3-diazo-2-oxopropyl]-L-phenylalaninamide 著者 Shenoy, R.T, Sivaraman, J. 登録日 2010-08-14 公開日 2010-12-08 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.761 Å) 主引用文献 Structural basis for reversible and irreversible inhibition of human cathepsin L by their respective dipeptidyl glyoxal and diazomethylketone inhibitors. J.Struct.Biol., 173, 2011
2RCB	Crystal structure of the NR3B ligand binding core complex with D-serine at 1.62 Angstrom resolution 分子名称: D-SERINE, GLYCEROL, Glutamate [NMDA] receptor subunit 3B 著者 Yao, Y, Mayer, M.L. 登録日 2007-09-19 公開日 2008-08-05 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors. Embo J., 27, 2008
4HLD	Sulfonylpiperidines as Novel, Antibacterial Inhibitors of Gram-Positive Thymidylate Kinase (TMK): Compound 11 分子名称: 1-[(3S)-1-{[3-(3-chlorophenoxy)-4-hydroxyphenyl]sulfonyl}piperidin-3-yl]-5-methylpyrimidine-2,4(1H,3H)-dione, Thymidylate kinase 著者 Olivier, N. 登録日 2012-10-16 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Sulfonylpiperidines as novel, antibacterial inhibitors of Gram-positive thymidylate kinase (TMK). Bioorg.Med.Chem.Lett., 23, 2013
1SW1	Crystal structure of ProX from Archeoglobus fulgidus in complex with proline betaine 分子名称: 1,1-DIMETHYL-PROLINIUM, ZINC ION, osmoprotection protein (proX) 著者 Schiefner, A, Holtmann, G, Diederichs, K, Welte, W, Bremer, E. 登録日 2004-03-30 公開日 2004-09-14 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for the binding of compatible solutes by ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus. J.Biol.Chem., 279, 2004
3S68	Rat COMT in complex with SAM and Tolcapone at 1.85A, P3221, Rfree=22.0 分子名称: CHLORIDE ION, Catechol O-methyltransferase, MAGNESIUM ION, ... 著者 Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G. 登録日 2011-05-25 公開日 2012-02-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Catechol-O-methyltransferase in complex with substituted 3'-deoxyribose bisubstrate inhibitors Acta Crystallogr.,Sect.D, 68, 2012
4KOY	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cephalosporin C 分子名称: 1,2-ETHANEDIOL, 4-(3-ACETOXYMETHYL-2-CARBOXY-8-OXO-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2-EN-7-YLCARBAMOYL)-1-CARBOXY-BUTYL-AMMONIUM, SULFATE ION, ... 著者 Majorek, K.A, Porebski, P.J, Chruszcz, M, Cymborowski, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2013-05-12 公開日 2013-06-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA. J.Biol.Chem., 288, 2013
1E0F	Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor 分子名称: HAEMADIN, THROMBIN 著者 Richardson, J.L, Kroeger, B, Hoefken, W, Pereira, P, Huber, R, Bode, W, Fuentes-Prior, P. 登録日 2000-03-27 公開日 2000-11-03 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of the Human Alpha-Thrombin-Haemadin Complex: An Exosite II-Binding Inhibitor Embo J., 19, 2000
4KRA	Salmonella typhi OmpF complex with Ciprofloxacin 分子名称: 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Outer membrane protein F 著者 Madhuranayaki, T, Balasubramaniam, D, Krishnaswamy, S. 登録日 2013-05-16 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 Salmonella typhi OmpF complex with Ciprofloxacin To be published
2RJ4	B-specific alpha-1,3-galactosyltransferase G176R +UDP+ADA 分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... 著者 Evans, S.V, Alfaro, J.A. 登録日 2007-10-14 公開日 2008-02-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes. J.Biol.Chem., 283, 2008
2EG7	The crystal structure of E. coli dihydroorotase complexed with HDDP 分子名称: 2-OXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4,6-DICARBOXYLIC ACID, Dihydroorotase, ZINC ION 著者 Lee, M, Maher, M.J, Guss, J.M. 登録日 2007-02-28 公開日 2007-07-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of Ligand-free and Inhibitor Complexes of Dihydroorotase from Escherichia coli: Implications for Loop Movement in Inhibitor Design J.Mol.Biol., 370, 2007
3SGH	Crystal structure of a SusD-like protein (BT_3752) from Bacteroides thetaiotaomicron VPI-5482 at 1.70 A resolution 分子名称: CHLORIDE ION, SusD homolog 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-06-14 公開日 2011-07-06 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of a Hypothetical SusD-like protein (BT_3752) from Bacteroides thetaiotaomicron VPI-5482 at 1.70 A resolution To be published

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