8Z9E
 
 | | Cryo-EM structure of NTR-bound type VII CRISPR-Cas complex at substrate-engaged state II | | 分子名称: | Protein structure, RNA (34-MER), RNA (39-MER), ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-04-23 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
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8Z9C
 | | Cryo-EM structure of NTR-bound type VII CRISPR-Cas complex at substrate-engaged state I | | 分子名称: | Protein structure, RNA (41-MER), RNA (48-MER), ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-04-23 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
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9RSA
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8ZLI
 | | BTA-2-bound E46K alpha-synuclein fibrils | | 分子名称: | Alpha-synuclein, ~{N},~{N}-dimethyl-4-(6-methyl-1,3-benzothiazol-2-yl)aniline | | 著者 | Liu, K.E, Tao, Y.Q, Li, D, Liu, C. | | 登録日 | 2024-05-20 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8Z4J
 | | Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at substrate-engaged state II | | 分子名称: | Protein structure, RNA (34-MER), RNA (38-MER), ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-04-17 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
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8ZLO
 | | F0502B-bound E46K alpha-synuclein fibril | | 分子名称: | 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein | | 著者 | Liu, K.E, Tao, Y.Q, Li, D, Liu, C. | | 登録日 | 2024-05-20 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9AT8
 | | Fab 77-stabilized MeV F ectodomain fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAB 77 heavy chain, ... | | 著者 | Zyla, D, Saphire, E.O. | | 登録日 | 2024-02-26 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
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9FII
 | | Crystal Structure of oxidized NuoEF variant E222K(NuoF) from Aquifex aeolicus | | 分子名称: | CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Wohlwend, D, Friedrich, T, Goeppert-Asadollahpour, S. | | 登録日 | 2024-05-29 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I).
Biochim Biophys Acta Bioenerg, 1865, 2024
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9CSG
 | | Human Serum Albumin Bound to Cerastecin Compound 5e | | 分子名称: | 2-(4-butylbenzene-1-sulfonamido)-5-(4-{3-carboxy-4-[4-(2-methoxyethyl)benzene-1-sulfonamido]anilino}-4-oxobutanamido)benzoic acid, Albumin, MYRISTIC ACID | | 著者 | Hruza, A, Klein, D.J, Ishchenko, A. | | 登録日 | 2024-07-23 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.914 Å) | | 主引用文献 | Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy.
J.Med.Chem., 67, 2024
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8ZMY
 | | F0502B-bound WT polymorph 5a alpha-synuclein fibril | | 分子名称: | 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein | | 著者 | Liu, K.E, Tao, Y.Q, Li, D, Liu, C. | | 登録日 | 2024-05-24 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8ZLP
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9B3P
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9AZ4
 | | INF2 at the Barbed End of F-Actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Palmer, N.J, Barrie, K.R, Dominguez, R. | | 登録日 | 2024-03-10 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Mechanisms of actin filament severing and elongation by formins.
Nature, 632, 2024
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2BCV
 | | DNA polymerase lambda in complex with Dttp and a DNA duplex containing an unpaired Dtmp | | 分子名称: | 5'-D(*CP*AP*GP*TP*AP*(O2C))-3', 5'-D(*CP*GP*GP*CP*AP*GP*TP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | | 登録日 | 2005-10-19 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase
Cell(Cambridge,Mass.), 124, 2006
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9AZQ
 | | INF2 at the Barbed End of F-Actin with Incoming Actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Palmer, N.J, Barrie, K.R, Dominguez, R. | | 登録日 | 2024-03-11 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | Mechanisms of actin filament severing and elongation by formins.
Nature, 632, 2024
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9EO2
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9CLP
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8XVI
 | | Cryo-EM structure of ETAR bound with Endothelin1 | | 分子名称: | Endoglucanase H,Endothelin-1 receptor, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
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8XVL
 | | Cryo-EM structure of ETAR bound with Zibotentan | | 分子名称: | Endoglucanase H,Endothelin-1 receptor,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
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8XVJ
 | | Cryo-EM structure of ETAR bound with Macitentan | | 分子名称: | 6-[2-(5-bromanylpyrimidin-2-yl)oxyethoxy]-5-(4-bromophenyl)-~{N}-(propylsulfamoyl)pyrimidin-4-amine, Endoglucanase H,Endothelin-1 receptor,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
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9B0K
 | | INF2 in the Middle of F-Actin (Down state) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Palmer, N.J, Barrie, K.R, Dominguez, R. | | 登録日 | 2024-03-12 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Mechanisms of actin filament severing and elongation by formins.
Nature, 632, 2024
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9ENZ
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8XVK
 | | Cryo-EM structure of ETAR bound with Ambrisentan | | 分子名称: | (2~{S})-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenyl-propanoic acid, Endoglucanase H,Endothelin-1 receptor,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
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8XVE
 | | Cryo-EM structure of ETBR bound with BQ3020 | | 分子名称: | BQ3020, Exo-alpha-sialidase,Endothelin receptor type B, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
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8XVH
 | | Cryo-EM structure of ETBR bound with Endothelin1 | | 分子名称: | Endothelin-1, Exo-alpha-sialidase,Endothelin receptor type B, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Hou, J.Y, Liu, S.H, Wu, L.J, Liu, Z.J, Hua, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural basis of antagonist selectivity in endothelin receptors.
Cell Discov, 10, 2024
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