6H7O
 
 | | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND WEAK PARTIAL AGONIST CYANOPINDOLOL AND NANOBODY Nb6B9 | | 分子名称: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, ... | | 著者 | Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. | | 登録日 | 2018-07-31 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
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6H7L
 | | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST DOBUTAMINE AND NANOBODY Nb6B9 | | 分子名称: | Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, DOBUTAMINE, ... | | 著者 | Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. | | 登録日 | 2018-07-31 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
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6H7J
 | | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST ISOPRENALINE AND NANOBODY Nb80 | | 分子名称: | Beta-1 adrenergic receptor, Camelid antibody fragment Nb80, HEGA-10, ... | | 著者 | Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. | | 登録日 | 2018-07-31 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
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6IBL
 | | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST FORMOTEROL AND NANOBODY Nb80 | | 分子名称: | Camelid antibody fragment Nb80, HEGA-10, SODIUM ION, ... | | 著者 | Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. | | 登録日 | 2018-11-30 | | 公開日 | 2019-01-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor.
Nature, 583, 2020
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6J11
 | | MERS-CoV spike N-terminal domain and 7D10 scFv complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-terminal domain of Spike glycoprotein, ... | | 著者 | Zhou, H, Zhang, S, Zhang, S, Tang, W, Wang, X. | | 登録日 | 2018-12-27 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein.
Nat Commun, 10, 2019
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7DQ7
 | | Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 5F5 | | 分子名称: | 5F5 VH, 5F5 VL, Capsid protein VP4, ... | | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | | 登録日 | 2020-12-22 | | 公開日 | 2021-05-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
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5HM1
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6MHR
 | | Structure of the human 4-1BB / Urelumab Fab complex | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, MALONATE ION, ... | | 著者 | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | | 登録日 | 2018-09-18 | | 公開日 | 2018-11-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.
Nat Commun, 9, 2018
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6MI2
 | | Structure of the human 4-1BB / Utomilumab Fab complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... | | 著者 | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | | 登録日 | 2018-09-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.
Nat Commun, 9, 2018
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2VQ1
 | | anti trimeric Lewis X Fab54-5C10-A | | 分子名称: | ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION, AZIDE ION, GLYCEROL, ... | | 著者 | de Geus, D.C, van Roon, A.M.M, Thomassen, E.A.J, Hokke, C.H, Deelder, A.M, Abrahams, J.P. | | 登録日 | 2008-03-10 | | 公開日 | 2009-01-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Characterization of a Diagnostic Fab Fragment Binding Trimeric Lewis X.
Proteins, 76, 2009
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7FIG
 | | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid antibody VHH fragment Nb35, Choriogonadotropin subunit beta 3, ... | | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | | 登録日 | 2021-07-31 | | 公開日 | 2021-09-29 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
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6Y0L
 | | Crystal structure of human CD23 lectin domain N225D, K229E, S252N, T251N, R253G, S254G mutant | | 分子名称: | GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, SULFATE ION | | 著者 | Ilkow, V.F, Davies, A.M, Sutton, B.J, McDonnell, J.M. | | 登録日 | 2020-02-09 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Reviving lost binding sites: Exploring calcium-binding site transitions between human and murine CD23.
Febs Open Bio, 11, 2021
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6Y0M
 | | Crystal structure of human CD23 lectin domain N225D, K229E, S252N, T251N mutant | | 分子名称: | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | | 著者 | Ilkow, V.F, Davies, A.M, Sutton, B.J, McDonnell, J.M. | | 登録日 | 2020-02-09 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Reviving lost binding sites: Exploring calcium-binding site transitions between human and murine CD23.
Febs Open Bio, 11, 2021
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6Z6V
 | | Globular head of C1q in complex with the nanobody C1qNb75 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, ... | | 著者 | Laursen, N.S, Andersen, G.R. | | 登録日 | 2020-05-29 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System.
Front Immunol, 11, 2020
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2OCW
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6ZXN
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6ZLR
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6PXR
 | | Anti-TAU BIIB092 FAB with TAU peptide | | 分子名称: | Microtubule-associated protein tau, gosuranemab Fab, heavy chain, ... | | 著者 | Arndt, J.W, Quan, C. | | 登録日 | 2019-07-26 | | 公開日 | 2020-07-29 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (1.556 Å) | | 主引用文献 | Characterization of tau binding by gosuranemab.
Neurobiol.Dis., 146, 2020
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6SVL
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7UIJ
 | | Structural studies of B5-OspC complex | | 分子名称: | 1,2-ETHANEDIOL, Monoclonal B5 Fab Heavy Chain, Monoclonal B5 Fab Light Chain, ... | | 著者 | Rudolph, M.J, Mantis, N. | | 登録日 | 2022-03-29 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.
Mbio, 14, 2023
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6SUZ
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7VNG
 | | Crystal structure of human coronavirus 229E spike protein receptor-binding domain in complex with S11 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S11 Fab heavy chain, S11 Fab light chain, ... | | 著者 | Xiang, J.C, Zhao, W.W, Yang, B. | | 登録日 | 2021-10-11 | | 公開日 | 2022-10-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.
Commun Biol, 5, 2022
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7VN9
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1S6Q
 | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R147681 | | 分子名称: | 4-[4-(2,4,6-TRIMETHYL-PHENYLAMINO)-PYRIMIDIN-2-YLAMINO]-BENZONITRILE, POL polyprotein [Contains: Reverse transcriptase] | | 著者 | Das, K, Arnold, E. | | 登録日 | 2004-01-26 | | 公開日 | 2004-05-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants.
J.Med.Chem., 47, 2004
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1S6P
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