6H7J
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST ISOPRENALINE AND NANOBODY Nb80
Summary for 6H7J
Entry DOI | 10.2210/pdb6h7j/pdb |
Descriptor | Thioredoxin 1, Beta-1 adrenergic receptor, Camelid antibody fragment Nb80, ... (7 entities in total) |
Functional Keywords | beta1 adrenoceptor, activated, agonist, nanobody, immune system |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 6 |
Total formula weight | 122024.98 |
Authors | Warne, T.,Edwards, P.C.,Dore, A.S.,Leslie, A.G.W.,Tate, C.G. (deposition date: 2018-07-31, release date: 2018-10-17, Last modification date: 2024-01-17) |
Primary citation | Warne, T.,Edwards, P.C.,Dore, A.S.,Leslie, A.G.W.,Tate, C.G. Molecular basis for high-affinity agonist binding in GPCRs. Science, 364:775-778, 2019 Cited by PubMed: 31072904DOI: 10.1126/science.aau5595 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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