PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4WAE	Phosphatidylinositol 4-kinase III beta crystallized with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta 著者 Chalupska, D, Boura, E. 登録日 2014-08-29 公開日 2015-05-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.318 Å) 主引用文献 Highly Selective Phosphatidylinositol 4-Kinase III beta Inhibitors and Structural Insight into Their Mode of Action. J.Med.Chem., 58, 2015
4WBA	Q/E mutant SA11 NSP4_CCD 分子名称: GLYCEROL, Non-structural glycoprotein NSP4, PHOSPHATE ION 著者 Viskovska, M, Sastri, N.P, Hyser, J.M, Tanner, M.R, Horton, L.B, Sankaran, B, Prasad, B.V.V, Estes, M.K. 登録日 2014-09-02 公開日 2014-09-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4. J.Virol., 88, 2014
7RAG	Structure of the CwlD amidase from Clostridioides difficile in complex with the GerS lipoprotein 分子名称: 1,2-ETHANEDIOL, Germination-specific N-acetylmuramoyl-L-alanine amidase, Autolysin, ... 著者 Eckenroth, B.E, Doublie, S. 登録日 2021-07-01 公開日 2021-09-08 最終更新日 2021-10-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A lipoprotein allosterically activates the CwlD amidase during Clostridioides difficile spore formation. Plos Genet., 17, 2021
2G19	Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) 分子名称: Egl nine homolog 1, FE (II) ION, N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE 著者 Syed, R.S, Li, V. 登録日 2006-02-14 公開日 2006-06-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2). Proc.Natl.Acad.Sci.Usa, 103, 2006
4WCV	Haloalkane dehalogenase DhaA mutant from Rhodococcus rhodochrous (T148L+G171Q+A172V+C176G) 分子名称: ACETATE ION, CHLORIDE ION, Haloalkane dehalogenase, ... 著者 Holubeva, T, Prudnikova, T, Kuta-Smatanova, I, Rezacova, P. 登録日 2014-09-05 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Balancing the stability-activity trade-off by fine-tuning dehalogenase access tunnels Chemcatchem, 2015
4WD1	Acetoacetyl-CoA Synthetase from Streptomyces lividans 分子名称: 1,2-ETHANEDIOL, Acetoacetate-CoA ligase, CALCIUM ION 著者 Gulick, A.M, Mitchell, C.A. 登録日 2014-09-05 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 The structure of S. lividans acetoacetyl-CoA synthetase shows a novel interaction between the C-terminal extension and the N-terminal domain. Proteins, 83, 2015
2G1M	Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) 分子名称: Egl nine homolog 1, FE (II) ION, N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE 著者 Mcdonough, M.A, Schofield, C.J. 登録日 2006-02-14 公開日 2006-06-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2). Proc.Natl.Acad.Sci.Usa, 103, 2006
4W8Y	Structure of full length Cmr2 from Pyrococcus furiosus (Manganese bound form) 分子名称: CRISPR system Cmr subunit Cmr2, MANGANESE (II) ION, ZINC ION 著者 Benda, C, Ebert, J, Baumgaertner, M, Conti, E. 登録日 2014-08-26 公開日 2014-10-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4. Mol.Cell, 56, 2014
4WA0	The structure of a possible adhesin C-terminal domain from Caldicellulosiruptor kronotskyensis 分子名称: MAGNESIUM ION, possible adhesin 著者 Alahuhta, P.M, Lunin, V.V. 登録日 2014-08-28 公開日 2015-03-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discrete and Structurally Unique Proteins (Tapirins) Mediate Attachment of Extremely Thermophilic Caldicellulosiruptor Species to Cellulose. J.Biol.Chem., 290, 2015
4F9V	Structure of C113A/C136A mutant variant of glycosylated glutaminyl cyclase from Drosophila melanogaster 分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, CG32412, DI(HYDROXYETHYL)ETHER, ... 著者 Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T. 登録日 2012-05-21 公開日 2012-08-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs. Biochemistry, 51, 2012
4WA9	The crystal structure of human abl1 wild type kinase domain in complex with axitinib 分子名称: AXITINIB, Tyrosine-protein kinase ABL1 著者 Johnson, E, McTigue, M, Cronin, C.N. 登録日 2014-08-28 公開日 2015-02-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation. Nature, 519, 2015
7LDF	High resolution NMR solution structure of a de novo designed minimal thioredoxin fold protein 分子名称: Minimal thioredoxin fold protein, ems_thioM_802 著者 Urbauer, J.L, Strauch, E.M. 登録日 2021-01-13 公開日 2022-07-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Sampling of structure and sequence space of small protein folds. Nat Commun, 13, 2022
4WAU	Crystal structure of CENP-M solved by native-SAD phasing 分子名称: Centromere protein M 著者 Weinert, T, Basilico, F, Cecatiello, V, Pasqualato, S, Wang, M. 登録日 2014-09-01 公開日 2014-12-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015
7LRW	Structure of Hact-2 分子名称: Hact-2 著者 Schmidt, C.A, Daly, N.L. 登録日 2021-02-17 公開日 2022-08-03 実験手法 SOLUTION NMR 主引用文献 Diversity of coral derived peptides To Be Published
7YCK	Crystal structure of SARS-CoV-2 Spike RBD in complex with FP-12A Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FP-12A Fab heavy chain, FP-12A Fab light chain, ... 著者 Nguyen, V.H.T, Chen, X. 登録日 2022-07-01 公開日 2023-02-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2. Nat Commun, 14, 2023
7LT7	Structure of Hact-3 分子名称: Hact-3 著者 Schmidt, C.A, Daly, N.L. 登録日 2021-02-19 公開日 2022-08-03 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Diversity of coral derived peptides To Be Published
7YCL	Crystal structure of SARS-CoV-2 Spike RBD in complex with IS-9A Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IS-9A Fab heavy chain, IS-9A Fab light chain, ... 著者 Mohapatra, A, Chen, X. 登録日 2022-07-01 公開日 2023-02-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2. Nat Commun, 14, 2023
7LX4	Structure of Hact-SCRiP1 分子名称: Hact-SCRiP1 著者 Schmidt, C.A, Daly, N.L. 登録日 2021-03-03 公開日 2022-08-03 実験手法 SOLUTION NMR 主引用文献 Diversity of coral derived peptides To Be Published
7LMX	A HIGHLY SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 WITH A DISULFIDE 分子名称: Integrin inhibitor 著者 Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D. 登録日 2021-02-06 公開日 2022-08-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
7RMR	Crystal structure of [I11L]cycloviolacin O2 分子名称: D-[I11L]cycloviolacin O2, THIOCYANATE ION, [I11L]cycloviolacin O2 著者 Huang, Y.H, Du, Q, Craik, D.J. 登録日 2021-07-28 公開日 2021-09-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides. Molecules, 26, 2021
4WD7	Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae by Zn-SAD phasing 分子名称: Bestrophin domain protein, ZINC ION 著者 Yang, T, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2014-09-08 公開日 2014-10-01 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure and selectivity in bestrophin ion channels. Science, 346, 2014
7RS8	Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with DMERI-16 分子名称: (1R,2S,4R)-5-(4-hydroxyphenyl)-N-(4-methoxyphenyl)-6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor 著者 Min, J, Nwachukwu, J.C, Min, C.K, Njeri, J.W, Srinivasan, S, Rangarajan, E.S, Nettles, C.C, Yan, S, Houtman, R, Griffin, P.R, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. 登録日 2021-08-11 公開日 2021-09-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Dual-mechanism estrogen receptor inhibitors. Proc.Natl.Acad.Sci.USA, 118, 2021
7LMV	SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 分子名称: Integrin inhibitor 著者 Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D. 登録日 2021-02-05 公開日 2022-08-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
4WB4	wt SA11 NSP4_CCD 分子名称: CALCIUM ION, Non-structural glycoprotein NSP4 著者 Viskovska, M, Sastri, N.P, Hyser, J.M, Tanner, M.R, Horton, L.B, Sankaran, B, Prasad, B.V.V, Estes, M.K. 登録日 2014-09-02 公開日 2014-09-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4. J.Virol., 88, 2014
7RRX	Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with DMERI-19 分子名称: (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-N-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, CHLORIDE ION, Estrogen receptor 著者 Min, J, Nwachukwu, J.C, Min, C.K, Njeri, J.W, Srinivasan, S, Rangarajan, E.S, Nettles, C.C, Yan, S, Houtman, R, Griffin, P.R, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. 登録日 2021-08-10 公開日 2021-09-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Dual-mechanism estrogen receptor inhibitors. Proc.Natl.Acad.Sci.USA, 118, 2021

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