8OLM
| Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI1 | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{S},5~{S},8~{S},13~{R},14~{R})-5,14-dimethyl-16-oxidanylidene-1,2,3,4,6,7,8,11,12,13,15,17-dodecahydrocyclopenta[a]phenanthren-3-yl] sulfamate | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | 登録日 | 2023-03-30 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl To Be Published
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8OMP
| Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI33 | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},15~{R})-10,13,15-trimethyl-17-oxidanylidene-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl] sulfamate | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | 登録日 | 2023-03-31 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl To Be Published
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8OKO
| Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_2 | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{S},8~{S},9~{S},10~{R},13~{S},14~{S})-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | 登録日 | 2023-03-28 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
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8OO8
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8OLI
| Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI_12 | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{S},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | 登録日 | 2023-03-30 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl To Be Published
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8OMB
| Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl VK42 | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(8~{R},9~{S},13~{S},14~{S})-13-methyl-17-oxidanylidene-7,8,9,11,12,14,15,16-octahydro-6~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | 登録日 | 2023-03-31 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl To Be Published
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8OMH
| Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl (BS1982) | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(8~{S},9~{S},13~{S},14~{S})-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfamate | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | 登録日 | 2023-03-31 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
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1RAY
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1RJ6
| Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV in Complex with Acetazolamide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase XIV, ... | 著者 | Whittington, D.A, Grubb, J.H, Waheed, A, Shah, G.N, Sly, W.S, Christianson, D.W. | 登録日 | 2003-11-18 | 公開日 | 2004-03-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes. J.Biol.Chem., 279, 2004
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8OKG
| Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_13 | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{S},8~{S},9~{S},10~{R},13~{S},14~{S},17~{S})-17-methanoyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | 登録日 | 2023-03-28 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
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8OTP
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3D9Z
| Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties | 分子名称: | 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | 著者 | Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. | 登録日 | 2008-05-28 | 公開日 | 2009-03-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
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8OUB
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3DCS
| Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties | 分子名称: | Carbonic anhydrase 2, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ZINC ION | 著者 | Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. | 登録日 | 2008-06-04 | 公開日 | 2009-03-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
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3D92
| Human carbonic anhydrase II bound with substrate carbon dioxide | 分子名称: | CARBON DIOXIDE, GLYCEROL, ZINC ION, ... | 著者 | Domsic, J.F, Avvaru, B.S, McKenna, R. | 登録日 | 2008-05-26 | 公開日 | 2008-09-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Entrapment of carbon dioxide in the active site of carbonic anhydrase II J.Biol.Chem., 283, 2008
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3DA2
| X-ray structure of human carbonic anhydrase 13 in complex with inhibitor | 分子名称: | CHLORIDE ION, Carbonic anhydrase 13, N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide, ... | 著者 | Pilka, E.S, Picaud, S.S, Yue, W.W, King, O.N.F, Bray, J.E, Filippakopoulos, P, Roos, A.K, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Wikstrom, M, Edwards, A.M, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2008-05-28 | 公開日 | 2008-07-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | X-ray structure of human carbonic anhydrase 13 in complex with inhibitor. To be Published
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1LG5
| Crystal Structure Analysis of the HCA II Mutant T199P in complex with beta-mercaptoethanol | 分子名称: | BETA-MERCAPTOETHANOL, Carbonic anhydrase II, ZINC ION | 著者 | Huang, S, Sjoblom, B, Sauer-Eriksson, A.E, Jonsson, B.-H. | 登録日 | 2002-04-15 | 公開日 | 2002-07-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant. Biochemistry, 41, 2002
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6IM1
| Crystal structure of a highly thermostable carbonic anhydrase from Persephonella marina EX-H1 | 分子名称: | CALCIUM ION, Carbonic anhydrase (Carbonate dehydratase), TETRAETHYLENE GLYCOL, ... | 著者 | Jin, M.S, Kim, S, Sung, J, Yeon, J, Choi, S.H. | 登録日 | 2018-10-21 | 公開日 | 2019-07-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of a Highly Thermostable alpha-Carbonic Anhydrase from Persephonella marina EX-H1. Mol.Cells, 42, 2019
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6HXD
| Human Carbonic Anhydrase II in complex with 4-Butylbenzenesulfonamide | 分子名称: | 4-butylbenzenesulfonamide, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... | 著者 | Gloeckner, S, Heine, A, Klebe, G. | 登録日 | 2018-10-17 | 公開日 | 2019-10-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.119 Å) | 主引用文献 | Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors. Acs Chem.Biol., 15, 2020
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1KEQ
| Crystal Structure of F65A/Y131C Carbonic Anhydrase V, covalently modified with 4-chloromethylimidazole | 分子名称: | 4-METHYLIMIDAZOLE, ACETIC ACID, F65A/Y131C-MI Carbonic Anhydrase V, ... | 著者 | Jude, K.M, Wright, S.K, Tu, C, Silverman, D.N, Viola, R.E, Christianson, D.W. | 登録日 | 2001-11-16 | 公開日 | 2002-03-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle. Biochemistry, 41, 2002
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1LGD
| Crystal Structure Analysis of HCA II Mutant T199P in Complex with Bicarbonate | 分子名称: | BICARBONATE ION, Carbonic anhydrase II, ZINC ION | 著者 | Huang, S, Sjoblom, B, Sauer-Eriksson, A.E, Jonsson, B.-H. | 登録日 | 2002-04-15 | 公開日 | 2002-07-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant. Biochemistry, 41, 2002
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8Q3U
| Crystal structure of a fentanyl derivative in complex with human CA VII | 分子名称: | Carbonic anhydrase 7, GLYCEROL, ZINC ION, ... | 著者 | Alterio, V, Di Fiore, A, De Simone, G. | 登録日 | 2023-08-04 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for mu Opioid receptor for Safer and long-lasting analgesia. Eur.J.Med.Chem., 260, 2023
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3DVB
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6HR3
| Human Carbonic Anhydrase II in complex with 4-Propylbenzenesulfonamide | 分子名称: | 4-propylbenzenesulfonamide, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... | 著者 | Gloeckner, S, Heine, A, Klebe, G. | 登録日 | 2018-09-26 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors. Acs Chem.Biol., 15, 2020
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3CZV
| Crystal structure of the human carbonic anhydrase XIII in complex with acetazolamide | 分子名称: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 13, GLYCEROL, ... | 著者 | Di Fiore, A, De Simone, G. | 登録日 | 2008-04-30 | 公開日 | 2008-07-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide. Proteins, 74, 2008
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