1Z0F
 
 | | GDP-Bound Rab14 GTPase | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAB14, ... | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-01 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
|
|
1Z2A
 | | GDP-Bound Rab23 GTPase crystallized in P2(1)2(1)2(1) space group | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-23 | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-07 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
|
|
1YZQ
 | | GppNHp-Bound Rab6 GTPase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, small GTP binding protein RAB6 isoform | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-02-28 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
|
|
1Z06
 | | GppNHp-Bound Rab33 GTPase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-33B | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-01 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
|
|
1Z0D
 | | GDP-Bound Rab5c GTPase | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-01 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
|
|
1YVD
 | | GppNHp-Bound Rab22 GTPase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-22A | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-02-15 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
|
|
1YZT
 | | GppNHp-Bound Rab21 GTPase at 2.05 A Resolution | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-21 | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-02-28 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
|
|
1XTS
 | |
1ZW6
 | | Crystal Structure of the GTP-bound form of RasQ61G | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Ford, B, Hornak, V, Kleinman, H, Nassar, N. | | 登録日 | 2005-06-03 | | 公開日 | 2006-03-14 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a transient intermediate for GTP hydrolysis by ras.
Structure, 14, 2006
|
|
1ZVQ
 | |
1XJ0
 | |
221P
 | | THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES | | 分子名称: | H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Krengel, U, Scherer, A, Kabsch, W, Wittinghofer, A, Pai, E.F. | | 登録日 | 1991-06-06 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules.
Cell(Cambridge,Mass.), 62, 1990
|
|
2A5J
 | | Crystal Structure of Human RAB2B | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-2B | | 著者 | Dong, A, Wang, J, Shen, Y, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) | | 登録日 | 2005-06-30 | | 公開日 | 2005-07-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Crystal structure of human RAB2B
To be Published
|
|
1Z22
 | | GDP-Bound Rab23 GTPase crystallized in C222(1) space group | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-23 | | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | | 登録日 | 2005-03-07 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
|
|
1XTQ
 | |
6AGP
 | | Structure of Rac1 in the low-affinity state for Mg2+ | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Toyama, Y, Kontani, K, Katada, T, Shimada, I. | | 登録日 | 2018-08-13 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR.
Sci Adv, 5, 2019
|
|
6ARK
 | | Crystal Structure of compound 10 covalently bound to K-Ras G12C | | 分子名称: | (3R)-N-(6-bromonaphthalen-2-yl)-3-hydroxy-1-propanoyl-L-prolinamide, GLYCEROL, GTPase KRas, ... | | 著者 | Nnadi, C.I, Jenkins, M.L, Gentile, D.R, Bateman, L.A, Zaidman, D, Balius, T.E, Nomura, D.K, Burke, J.E, Shokat, K.M, London, N. | | 登録日 | 2017-08-22 | | 公開日 | 2018-01-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Novel K-Ras G12C Switch-II Covalent Binders Destabilize Ras and Accelerate Nucleotide Exchange.
J Chem Inf Model, 58, 2018
|
|
6B0V
 | | Crystal Structure of small molecule ARS-107 covalently bound to K-Ras G12C | | 分子名称: | 1-[3-(4-{[(4,5-dichloro-2-hydroxyphenyl)amino]acetyl}piperazin-1-yl)azetidin-1-yl]propan-1-one, CALCIUM ION, GTPase KRas, ... | | 著者 | Hansen, R, Peters, U, Babbar, A, Chen, Y, Feng, J, Janes, M.R, Li, L.-S, Ren, P, Liu, Y, Zarrinkar, P.P. | | 登録日 | 2017-09-15 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | The reactivity-driven biochemical mechanism of covalent KRASG12Cinhibitors.
Nat. Struct. Mol. Biol., 25, 2018
|
|
6B0Y
 | | Crystal Structure of small molecule ARS-917 covalently bound to K-Ras G12C | | 分子名称: | 1-{4-[6-chloro-7-(2-fluorophenyl)quinazolin-4-yl]piperazin-1-yl}propan-1-one, CALCIUM ION, GLYCEROL, ... | | 著者 | Hansen, R, Peters, U, Babbar, A, Chen, Y, Feng, J, Janes, M.R, Li, L.-S, Ren, P, Liu, Y, Zarrinkar, P.P. | | 登録日 | 2017-09-15 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | The reactivity-driven biochemical mechanism of covalent KRASG12Cinhibitors.
Nat. Struct. Mol. Biol., 25, 2018
|
|
6BP1
 | |
6BT0
 | | CRYSTAL STRUCTURE OF RHEB IN COMPLEX WITH COMPOUND NR1 | | 分子名称: | 4-bromo-6-[(3,4-dichlorophenyl)sulfanyl]-1-{[4-(dimethylcarbamoyl)phenyl]methyl}-1H-indole-2-carboxylic acid, GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Mahoney, S.J. | | 登録日 | 2017-12-04 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.
Nat Commun, 9, 2018
|
|
6CU6
 | |
6ASA
 | | KRAS mutant-D33E in GDP-bound | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Lu, J, Westover, K. | | 登録日 | 2017-08-24 | | 公開日 | 2018-01-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.545 Å) | | 主引用文献 | KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation.
Biochemistry, 57, 2018
|
|
6ASE
 | | KRAS mutant-A59G in GDP-bound | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Westover, K, Lu, J. | | 登録日 | 2017-08-24 | | 公開日 | 2018-01-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.554 Å) | | 主引用文献 | KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation.
Biochemistry, 57, 2018
|
|
6BOF
 | |
