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6BP1

Crystal structure of human KRAS A59G mutant in complex with GCP

Summary for 6BP1
Entry DOI10.2210/pdb6bp1/pdb
DescriptorGTPase KRas, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER (3 entities in total)
Functional Keywordshydrolase, small gtpase, signal transduction, gdp binding
Biological sourceHomo sapiens (Human)
Cellular locationCell membrane ; Lipid-anchor ; Cytoplasmic side : P01116
Total number of polymer chains1
Total formula weight19778.94
Authors
Bera, A.K.,Lu, J.,Westover, K.D. (deposition date: 2017-11-21, release date: 2018-01-24, Last modification date: 2023-10-04)
Primary citationLu, J.,Bera, A.K.,Gondi, S.,Westover, K.D.
KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation.
Biochemistry, 57:324-333, 2018
Cited by
PubMed: 29235861
DOI: 10.1021/acs.biochem.7b00974
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.001 Å)
Structure validation

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