6BP1
Crystal structure of human KRAS A59G mutant in complex with GCP
Summary for 6BP1
Entry DOI | 10.2210/pdb6bp1/pdb |
Descriptor | GTPase KRas, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER (3 entities in total) |
Functional Keywords | hydrolase, small gtpase, signal transduction, gdp binding |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01116 |
Total number of polymer chains | 1 |
Total formula weight | 19778.94 |
Authors | Bera, A.K.,Lu, J.,Westover, K.D. (deposition date: 2017-11-21, release date: 2018-01-24, Last modification date: 2023-10-04) |
Primary citation | Lu, J.,Bera, A.K.,Gondi, S.,Westover, K.D. KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation. Biochemistry, 57:324-333, 2018 Cited by PubMed: 29235861DOI: 10.1021/acs.biochem.7b00974 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.001 Å) |
Structure validation
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