6BP1
Crystal structure of human KRAS A59G mutant in complex with GCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase KRas | polymer | 169 | 19257.7 | 1 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras |
| 2 | B (A) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 1 | Chemie (GCP) | |||
| 3 | C (A) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 1 - 169 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly 59 | Ala 59 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19257.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 521.2 | |
| All* | Total formula weight | 19778.9 |
