3J99
 
 | | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIb) | | 分子名称: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | 著者 | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | 登録日 | 2014-12-05 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | | 主引用文献 | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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2VGQ
 | | Crystal Structure of Human IPS-1 CARD | | 分子名称: | SULFATE ION, Sugar ABC transporter substrate-binding protein,Mitochondrial antiviral-signaling protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Potter, J.A, Randall, R.E, Taylor, G.L. | | 登録日 | 2007-11-15 | | 公開日 | 2007-12-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of Human Ips-1 Caspase Activation Recruitment Domain
Bmc Struct.Biol., 8, 2008
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3J96
 | | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State I) | | 分子名称: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | 著者 | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | 登録日 | 2014-12-05 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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5UDR
 | | LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with nicotinamide mononucleotid NMN | | 分子名称: | ATP-utilizing enzyme of the PP-loopsuperfamily, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, MANGANESE (II) ION | | 著者 | Fellner, M, Desguin, B, Hausinger, R.P, Hu, J. | | 登録日 | 2016-12-28 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3JC1
 | | Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer | | 分子名称: | Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1) | | 著者 | McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A. | | 登録日 | 2015-11-09 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure and membrane remodeling activity of ESCRT-III helical polymers.
Science, 350, 2015
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3BGQ
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3J98
 | | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa) | | 分子名称: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | 著者 | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | 登録日 | 2014-12-05 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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3J94
 | | Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vesicle-fusing ATPase | | 著者 | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | 登録日 | 2014-12-05 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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3JR6
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3BGZ
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1UNE
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5UNM
 | | LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, substrate free form with flexible loop | | 分子名称: | ATP-utilizing enzyme of the PP-loopsuperfamily, PHOSPHATE ION | | 著者 | Fellner, M, Desguin, B, Hausinger, R.P, Hu, J. | | 登録日 | 2017-01-31 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3J9B
 | | Electron cryo-microscopy of an RNA polymerase | | 分子名称: | Polymerase, Polymerase basic protein 2, RNA (5'-R(*UP*UP*UP*UP*UP*A)-3'), ... | | 著者 | Chang, S.H, Sun, D.P, Liang, H.H, Wang, J, Li, J, Guo, L, Wang, X.L, Guan, C.C, Boruah, B.M, Yuan, L.M, Feng, F, Yang, M.R, Wojdyla, J, Wang, J.W, Wang, M.T, Wang, H.W, Liu, Y.F. | | 登録日 | 2014-12-16 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution.
Mol.Cell, 2015
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3JA6
 | | Cryo-electron Tomography and All-atom Molecular Dynamics Simulations Reveal a Novel Kinase Conformational Switch in Bacterial Chemotaxis Signaling | | 分子名称: | Chemotaxis protein CheA, Chemotaxis protein CheW, Methyl-accepting chemotaxis protein 2 | | 著者 | Cassidy, C.K, Himes, B.A, Alvarez, F.J, Ma, J, Zhao, G, Perilla, J.R, Schulten, K, Zhang, P. | | 登録日 | 2015-04-21 | | 公開日 | 2015-12-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (12.7 Å) | | 主引用文献 | CryoEM and computer simulations reveal a novel kinase conformational switch in bacterial chemotaxis signaling.
Elife, 4, 2015
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2K7S
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2GRT
 | | HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, OXIDIZED GLUTATHIONE COMPLEX | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, OXIDIZED GLUTATHIONE DISULFIDE | | 著者 | Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F. | | 登録日 | 1997-02-12 | | 公開日 | 1997-08-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
Biochemistry, 36, 1997
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3AKZ
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2GYP
 | | Diabetes mellitus due to a frustrated Schellman motif in HNF-1a | | 分子名称: | Hepatocyte nuclear factor 1-alpha | | 著者 | Narayana, N, Phillips, N.B, Hua, Q.X, Jia, W, Weiss, M.A. | | 登録日 | 2006-05-09 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Diabetes mellitus due to misfolding of a beta-cell transcription factor: stereospecific frustration of a Schellman motif in HNF-1alpha.
J.Mol.Biol., 362, 2006
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1SHL
 | | CASPASE-7 IN COMPLEX WITH FICA ALLOSTERIC INHIBITOR | | 分子名称: | 5-FLUORO-1H-INDOLE-2-CARBOXYLIC ACID-(2-MERCAPTO-ETHYL)-AMIDE, Caspase-7 | | 著者 | Hardy, J.A, Lam, J, Nguyen, J.T, O'Brien, T, Wells, J.A. | | 登録日 | 2004-02-25 | | 公開日 | 2004-08-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Discovery of an allosteric site in the caspases
Proc.Natl.Acad.Sci.USA, 101, 2004
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1HZI
 | | INTERLEUKIN-4 MUTANT E9A | | 分子名称: | INTERLEUKIN-4, SULFATE ION | | 著者 | Hulsmeyer, M, Scheufler, C, Dreyer, M.K. | | 登録日 | 2001-01-25 | | 公開日 | 2001-08-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of interleukin 4 mutant E9A suggests polar steering in receptor-complex formation.
Acta Crystallogr.,Sect.D, 57, 2001
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1DGK
 | | MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH GLUCOSE AND ADP IN THE ACTIVE SITE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, HEXOKINASE TYPE I, PHOSPHATE ION, ... | | 著者 | Aleshin, A.E, Liu, X, Kirby, C, Bourenkov, G.P, Bartunik, H.D, Fromm, H.J, Honzatko, R.B. | | 登録日 | 1999-11-24 | | 公開日 | 2000-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation.
J.Mol.Biol., 296, 2000
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4OCC
 | | co-crystal structure of MDM2(17-111) in complex with compound 48 | | 分子名称: | E3 ubiquitin-protein ligase Mdm2, [(2R,5R,6R)-4-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid | | 著者 | Huang, X. | | 登録日 | 2014-01-08 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres.
J.Med.Chem., 57, 2014
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3LDH
 | | A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes | | 分子名称: | LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID | | 著者 | White, J.L, Hackert, M.L, Buehner, M, Adams, M.J, Ford, G.C, Lentzjunior, P.J, Smiley, I.E, Steindel, S.J, Rossmann, M.G. | | 登録日 | 1974-06-06 | | 公開日 | 1977-04-29 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes.
J.Mol.Biol., 102, 1976
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1NTL
 | | Model of mouse Crry-Ig determined by solution scattering, curve fitting and homology modelling | | 分子名称: | Complement component receptor 1-like protein,Ig gamma-1 chain C region secreted form | | 著者 | Aslam, M, Guthridge, J.M, Hack, B.K, Quigg, R.J, Holers, V.M, Perkins, S.J. | | 登録日 | 2003-01-30 | | 公開日 | 2004-02-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING (30 Å) | | 主引用文献 | The extended multidomain solution structures of the complement protein Crry
and its chimaeric conjugate Crry-Ig by scattering, analytical ultracentrifugation
and constrained modelling: implications for function and therapy
J.Mol.Biol., 329, 2003
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1EN6
 | | CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146L MUTANT | | 分子名称: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | | 著者 | Edwards, R.A, Whittaker, M.M, Baker, E.N, Whittaker, J.W, Jameson, G.B. | | 登録日 | 2000-03-20 | | 公開日 | 2001-06-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Biochemistry, 40, 2001
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