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6DIH
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BU of 6dih by Molmil
Crystal structure of Tdp1 catalytic domain in complex with Sigma Aldrich compound PH004941
分子名称: 1,2-ETHANEDIOL, 4-hydroxybenzene-1,2-dicarboxylic acid, Tyrosyl-DNA phosphodiesterase 1
著者Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S.
登録日2018-05-23
公開日2019-05-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening.
Nucleic Acids Res., 47, 2019
4UNO
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BU of 4uno by Molmil
Crystal structure of the ETS domain of human ETV5 in complex with DNA
分子名称: 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP)-3', CALCIUM ION, ...
著者Newman, J.A, Aitkenhead, H, Cooper, C.D.O, Pinkas, D.M, Shrestha, L, Burgess-Brown, N, Kopec, J, Fitzpatrick, F, Tallant, C, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Gileadi, O.
登録日2014-05-29
公開日2014-06-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
J.Biol.Chem., 290, 2015
4V5X
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BU of 4v5x by Molmil
The cryo-EM structure of a 3D DNA-origami object
分子名称: SCAFFOLD STRAND,SCAFFOLD STRAND, STAPLE STRAND
著者Bai, X.C, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2012-10-09
公開日2014-07-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (11.5 Å)
主引用文献Cryo-Em Structure of a 3D DNA-Origami Object.
Proc.Natl.Acad.Sci.USA, 109, 2012
7M5W
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BU of 7m5w by Molmil
Crystal structure of the HMG-C1 domain of human capicua bound to DNA
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*TP*TP*TP*TP*CP*AP*TP*TP*CP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*AP*TP*GP*AP*AP*TP*GP*AP*AP*AP*AP*AP*GP*C)-3'), ...
著者Webb, J.P, Liew, J.J.M, Gnann, A.D, Dowling, D.P.
登録日2021-03-25
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular basis of DNA recognition by the HMG-box-C1 module of Capicua
Biorxiv, 2022
8RM6
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BU of 8rm6 by Molmil
Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: C3(1)ARE
分子名称: C3(1)ARE_Chain C, C3(1)ARE_Chain D, Isoform 2 of Androgen receptor, ...
著者Lee, X.Y, Helsen, C, Van Eynde, W, Voet, A, Claessens, F.
登録日2024-01-05
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural mechanism underlying variations in DNA binding by the androgen receptor.
J.Steroid Biochem.Mol.Biol., 241, 2024
6R14
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BU of 6r14 by Molmil
Structure of kiteplatinated dsDNA
分子名称: Kiteplatin, Kiteplatinated DNA oligomer, chain A, ...
著者Margiotta, N, Papadia, P, Kubicek, K, Krejcikova, M, Gkionis, K, Sponer, J.
登録日2019-03-13
公開日2020-04-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of kiteplatinated DNA
To Be Published
4OGC
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BU of 4ogc by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
分子名称: ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ...
著者Jiang, F, Ma, E, Lin, S, Doudna, J.A.
登録日2014-01-15
公開日2014-02-12
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
7R08
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BU of 7r08 by Molmil
Abortive infection DNA polymerase Abi-P2
分子名称: Reverse transcriptase
著者Gapinska, M.A, Figiel, M, Czarnocki Cieciura, M, Nowotny, M, Zajko, W.
登録日2022-02-01
公開日2022-09-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
8G8J
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BU of 8g8j by Molmil
Crystal structure of human DNA polymerase eta incorporating ITP across dT
分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*TP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ...
著者Jung, H.
登録日2023-02-17
公開日2024-02-21
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of human DNA polymerase eta incorporating ITP across dT
To Be Published
8GBF
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BU of 8gbf by Molmil
Crystal structure of human DNA polymerase eta incorporating syn-ITP across dT
分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*TP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ...
著者Jung, H.
登録日2023-02-25
公開日2024-02-28
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal structure of human DNA polymerase eta incorporating syn-ITP across dT
To Be Published
6LBM
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BU of 6lbm by Molmil
Crystal Structure of FOXC2-DBD bound to a palindromic DNA sequence
分子名称: Forkhead box protein C2, IRE0, MAGNESIUM ION
著者Li, J, Dai, S.Y.
登録日2019-11-14
公開日2021-02-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.841 Å)
主引用文献Mechanism of forkhead transcription factors binding to a novel palindromic DNA site.
Nucleic Acids Res., 49, 2021
1VRO
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BU of 1vro by Molmil
Selenium-Assisted Nucleic Acid Crystallography: Use of Phosphoroselenoates for MAD Phasing of a DNA Structure
分子名称: 5'-D(*CP*(GMS)P*CP*GP*CP*G)-3', MAGNESIUM ION, SPERMINE
著者Wilds, C.J, Pattanayek, R, Pan, C, Wawrzak, Z, Egli, M.
登録日2005-04-14
公開日2005-04-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Selenium-Assisted Nucleic Acid Crystallography: Use of Phosphoroselenoates for MAD Phasing of a DNA Structure
J.Am.Chem.Soc., 124, 2002
4U6P
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BU of 4u6p by Molmil
Structural mechanism of error-free bypass of major benzo[a]pyrene adduct by human polymerase kappa
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*TP*AP*TP*GP*GP*TP*GP*AP*TP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*TP*CP*AP*C)-3'), ...
著者Jha, V.K, Ling, H.
登録日2014-07-29
公開日2016-01-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.593 Å)
主引用文献Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase kappa.
Nucleic Acids Res., 44, 2016
3UN0
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BU of 3un0 by Molmil
Crystal Structure of MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1, SULFATE ION
著者Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J.
登録日2011-11-15
公開日2011-12-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Nucleic Acids Res., 40, 2012
7R7J
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BU of 7r7j by Molmil
Crystal structure of RadD with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative DNA repair helicase RadD, ...
著者Osorio Garcia, M.A, Satyshur, K.A, Keck, J.L, Cox, M.M.
登録日2021-06-24
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献X-ray crystal structure of the Escherichia coli RadD DNA repair protein bound to ADP reveals a novel zinc ribbon domain.
Plos One, 17, 2022
1I0T
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BU of 1i0t by Molmil
0.6 A STRUCTURE OF Z-DNA CGCGCG
分子名称: 5'-D(*CP*GP*CP*GP*CP*G)-3', SPERMINE
著者Tereshko, V, Wilds, C.J, Minasov, G, Prakash, T.P, Maier, M.A, Howard, A, Wawrzak, Z, Manoharan, M, Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (0.6 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
7OPD
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BU of 7opd by Molmil
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5)
分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
著者Kokic, G, Cramer, P.
登録日2021-05-31
公開日2021-10-06
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7OPC
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BU of 7opc by Molmil
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4)
分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
著者Kokic, G, Cramer, P.
登録日2021-05-31
公開日2021-10-13
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
6R6D
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BU of 6r6d by Molmil
[Ru(TAP)2(11,12-CN2-dppz)]2+ bound to d(TCGGCGCCGA)2
分子名称: BARIUM ION, DNA (5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3'), Ruthenium (bis-(tetraazaphenanthrene)) (11,12-dicyano-dipyridophenazine), ...
著者McQuaid, K.T, Hall, J.P, Cardin, C.J.
登録日2019-03-27
公開日2020-05-06
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.838 Å)
主引用文献X-ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru-dppz Complexes.
Chemistry, 24, 2018
7R8I
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BU of 7r8i by Molmil
Crystal structure of Pseudooceanicola lipolyticus Argonaute bound to 5' OH guide DNA in the presence of Mg2+
分子名称: Argonaute, DNA (5'-D(*TP*TP*AP*CP*TP*GP*CP*AP*CP*AP*GP*GP*TP*GP*AP*CP*GP*A), MAGNESIUM ION
著者Shin, Y, Murakami, K.S.
登録日2021-06-26
公開日2022-11-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of Pseudooceanicola lipolyticus Argonaute bound to 5' OH guide DNA in the presence of Mg2+
To be published
7OO3
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BU of 7oo3 by Molmil
Pol II-CSB-CSA-DDB1-UVSSA (Structure1)
分子名称: CSB element, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
著者Kokic, G, Cramer, P.
登録日2021-05-26
公開日2021-10-06
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7OOB
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BU of 7oob by Molmil
Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ...
著者Kokic, G, Cramer, P.
登録日2021-05-27
公開日2021-10-13
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7O4I
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BU of 7o4i by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
著者Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
登録日2021-04-06
公開日2021-06-16
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O4J
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BU of 7o4j by Molmil
Yeast RNA polymerase II transcription pre-initiation complex (consensus)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
著者Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
登録日2021-04-06
公開日2021-06-16
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
8SKI
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BU of 8ski by Molmil
Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across HX
分子名称: 2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate), CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ...
著者Jung, H.
登録日2023-04-19
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.163 Å)
主引用文献Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA
To Be Published

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件を2024-09-04に公開中

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