7R7J
Crystal structure of RadD with ADP
Summary for 7R7J
| Entry DOI | 10.2210/pdb7r7j/pdb |
| Related | 6JDE |
| Descriptor | Putative DNA repair helicase RadD, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | atpase, sf2, dna binding protein |
| Biological source | Escherichia coli (strain K12) |
| Total number of polymer chains | 2 |
| Total formula weight | 134182.73 |
| Authors | Osorio Garcia, M.A.,Satyshur, K.A.,Keck, J.L.,Cox, M.M. (deposition date: 2021-06-24, release date: 2022-04-13, Last modification date: 2023-10-18) |
| Primary citation | Osorio Garcia, M.A.,Satyshur, K.A.,Cox, M.M.,Keck, J.L. X-ray crystal structure of the Escherichia coli RadD DNA repair protein bound to ADP reveals a novel zinc ribbon domain. Plos One, 17:e0266031-e0266031, 2022 Cited by PubMed Abstract: Genome maintenance is an essential process in all cells. In prokaryotes, the RadD protein is important for survival under conditions that include DNA-damaging radiation. Precisely how RadD participates in genome maintenance remains unclear. Here we present a high-resolution X-ray crystal structure of ADP-bound Escherichia coli RadD, revealing a zinc-ribbon element that was not modelled in a previous RadD crystal structure. Insights into the mode of nucleotide binding and additional structure refinement afforded by the new RadD model will help to drive investigations into the activity of RadD as a genome stability and repair factor. PubMed: 35482735DOI: 10.1371/journal.pone.0266031 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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