4U6P
Structural mechanism of error-free bypass of major benzo[a]pyrene adduct by human polymerase kappa
Summary for 4U6P
Entry DOI | 10.2210/pdb4u6p/pdb |
Related | 4U7C |
Descriptor | DNA polymerase kappa, DNA (5'-D(P*GP*CP*GP*GP*AP*TP*CP*AP*C)-3'), DNA (5'-D(*TP*AP*TP*GP*GP*TP*GP*AP*TP*CP*CP*GP*C)-3'), ... (7 entities in total) |
Functional Keywords | benzo[a]pyrene-n2-guanine, dna replication, dna damage tolerance, polymerase kappa, environment pollution, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9UBT6 |
Total number of polymer chains | 6 |
Total formula weight | 135014.63 |
Authors | |
Primary citation | Jha, V.,Bian, C.,Xing, G.,Ling, H. Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase kappa. Nucleic Acids Res., 44:4957-4967, 2016 Cited by PubMed: 27034468DOI: 10.1093/nar/gkw204 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.593 Å) |
Structure validation
Download full validation report