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4U6P

Structural mechanism of error-free bypass of major benzo[a]pyrene adduct by human polymerase kappa

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DNA polymerase kappapolymer52660184.72UniProt (Q9UBT6)
Pfam (PF00817)
Pfam (PF11798)
Pfam (PF11799)
Homo sapiens (Human)DINB protein,DINP
2C, E
(C, P)
DNA (5'-D(P*GP*CP*GP*GP*AP*TP*CP*AP*C)-3')polymer92740.82unidentified
3D, F
(D, T)
DNA (5'-D(*TP*AP*TP*GP*GP*TP*GP*AP*TP*CP*CP*GP*C)-3')polymer133982.62unidentified
4G, H, I, L, M...
(A, B)
MAGNESIUM IONnon-polymer24.36Chemie (MG)
5J, O
(A, B)
2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATEnon-polymer451.22Chemie (DCT)
6K
(B)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
7P, Q, R, S, T...
(A, B, C, D, P...)
waterwater18.0103Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight133816.3
Non-Polymers*Number of molecules9
Total formula weight1198.3
All*Total formula weight135014.6
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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