PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

---

4OD2	Crystal structure of the Fab fragment of an anti-DR5 antibody bound to DR5 分子名称: Fab fragment of drozitumab, heavy chain, light chain, ... 著者 Hymowitz, S.G, Compaan, D. 登録日 2014-01-09 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5. Cell Death Differ., 15, 2008
4YCE	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y mutant of human cellular retinoic acid binding proteinii with retinal at 1.95 angstrom- visible light irradiated crystal for 1 hour - 2nd cycle 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-02-19 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.953 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
4YCT	Endothiapepsin in complex with fragment 216 分子名称: 1,2-ETHANEDIOL, 4-(trifluoromethyl)benzenecarboximidamide, ACETATE ION, ... 著者 Stieler, M, Heine, A, Klebe, G. 登録日 2015-02-20 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
4YD3	Endothiapepsin in complex with fragment 224 分子名称: 2-(1H-indol-3-yl)-N-[(1-methyl-1H-pyrrol-2-yl)methyl]ethanamine, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Stieler, M, Heine, A, Klebe, G. 登録日 2015-02-20 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.248 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
4OWB	Cisplatin binding to HEWL under sodium bromide crystallisation conditions 分子名称: 2-methylprop-1-ene, ACETATE ION, BROMIDE ION, ... 著者 Tanley, S.W.M, Helliwell, J.R. 登録日 2014-01-31 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Chemical conversion of cisplatin and carboplatin with histidine in a model protein crystallized under sodium iodide conditions. Acta Crystallogr.,Sect.F, 70, 2014
4OWH	PtBr6 binding to HEWL 分子名称: ACETATE ION, BROMIDE ION, CHLORIDE ION, ... 著者 Tanley, S.W.M, Starkey, V.L, Lamplough, L, Kaenket, S, Helliwell, J.R. 登録日 2014-02-02 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.484 Å) 主引用文献 The binding of platinum hexahalides (Cl, Br and I) to hen egg-white lysozyme and the chemical transformation of the PtI6 octahedral complex to a PtI3 moiety bound to His15. Acta Crystallogr.,Sect.F, 70, 2014
6SFJ	Crystal structure of p38 alpha in complex with compound 77 (MCP41) 分子名称: Mitogen-activated protein kinase 14, ~{N}-[5-[[(2~{S})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]-2-methyl-phenyl]-1-(2-methylphenyl)pyrazole-4-carboxamide 著者 Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2019-08-01 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors. J.Med.Chem., 62, 2019
4YFR	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Y:R59Y mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.95 Angstrom Resolution - UV irradiated crystal for 30 minutes - 1st Cycle 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-02-25 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.952 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
6SGK	Nek2 kinase bound to inhibitor 102 分子名称: 2-phenylazanyl-9~{H}-purine-6-carbonitrile, Serine/threonine-protein kinase Nek2 著者 Richards, M.W, Mas-Droux, C.P, Bayliss, R. 登録日 2019-08-05 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase. Rsc Med Chem, 11, 2020
4YO4	Crystal Structure of DAPK1 catalytic domain in complex with the hinge binding fragment phthalazine 分子名称: ACETATE ION, CHLORIDE ION, Death-associated protein kinase 1, ... 著者 Grum-Tokars, V.L, Roy, S.M, Minasov, G, Anderson, W.F, Watterson, D.M. 登録日 2015-03-11 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of DAPK1 catalytic domain in complex with hinge binding fragments To Be Published
6F4V	Crystal structure of cleaved Kallistatin complexed with heparin at 1.8 Angstrom resolution 分子名称: 1,2-ETHANEDIOL, 3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, CHLORIDE ION, ... 著者 Zhou, A, Wei, Z. 登録日 2017-11-30 公開日 2018-12-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of human Kallistatin To Be Published
4YOA	Crsystal structure HIV-1 Protease MDR769 L33F Complexed with darunavir 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, HIV-1 Protease 著者 Kuiper, B.D, Keusch, B, Dewdney, T.G, Chordia, P, Brunzelle, J.S, Ross, K, Kovari, I.A, MacArthur, R, Salimnia, H, Kovari, L.C. 登録日 2015-03-11 公開日 2015-07-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.697 Å) 主引用文献 The L33F darunavir resistance mutation acts as a molecular anchor reducing the flexibility of the HIV-1 protease 30s and 80s loops. Biochem Biophys Rep, 2, 2015
6ETM	Atomic resolution structure of RNase A (data collection 3) 分子名称: ISOPROPYL ALCOHOL, Ribonuclease pancreatic 著者 Caterino, M, Vergara, A, Merlino, A. 登録日 2017-10-27 公開日 2018-02-21 実験手法 X-RAY DIFFRACTION (0.92 Å) 主引用文献 Raman-markers of X-ray radiation damage of proteins. Int. J. Biol. Macromol., 111, 2018
5T2E	Crystal Structure of multi-drug resistant HIV-1 protease PR-S17 分子名称: CHLORIDE ION, Protease 著者 Agniswamy, J, Weber, I.T. 登録日 2016-08-23 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics. PLoS ONE, 11, 2016
4YIA	Structural mechanism of hormone release in thyroxine binding globulin 分子名称: CALCIUM ION, CHLORIDE ION, INDOMETHACIN, ... 著者 Zheng, Y. 登録日 2015-03-01 公開日 2016-03-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structural mechanism of hormone release in thyroxine Binding globulin To Be Published
6SIJ	SAD structure of Hen Egg White Lysozyme recovered by continuous rotation data collection and multivariate analysis of Friedel pairs 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Garcia-Bonete, M.J, Katona, G. 登録日 2019-08-10 公開日 2019-11-06 最終更新日 2019-11-13 実験手法 X-RAY DIFFRACTION (1.61018026 Å) 主引用文献 Bayesian machine learning improves single-wavelength anomalous diffraction phasing. Acta Crystallogr.,Sect.A, 75, 2019
5T4S	Novel Approach of Fragment-Based Lead Discovery applied to Renin Inhibitors 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-N-[(furan-2-yl)methyl]pyrazin-2-amine, ... 著者 Snell, G.P, Behnke, C.A, Okada, K, Oki, H, Sang, B.C, Lane, W. 登録日 2016-08-30 公開日 2016-10-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Novel approach of fragment-based lead discovery applied to renin inhibitors. Bioorg.Med.Chem., 24, 2016
6R6X	Crystal structure of di-phosphorylated human CLK1 in complex with 5-(1-methyl-1H-indol-3-yl)pyrimidin-4-amine 分子名称: 5-(1-methylindol-3-yl)pyrimidin-4-amine, Dual specificity protein kinase CLK1 著者 Livnah, O, Domovich, Y. 登録日 2019-03-28 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of di-phosphorylated human CLK1 in complex with 5-(1-methyl-1H-indol-3-yl)pyrimidin-4-amine To Be Published
4YKM	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32W:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-03-04 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
5SW7	Structure of the Human Hemoglobin Mutant Hb Providence (A-Gly-C:V1M; B,D:V1M,K82D; Ferrous, carbonmonoxy bound) 分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Soman, J, Olson, J.S. 登録日 2016-08-08 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Structure of the Human Hemoglobin Mutant Hb Providence (A-Gly-C:V1M; B,D:V1M,K82D; Ferrous, carbonmonoxy bound) To Be Published
6F9M	The LIPY/F-motif in an intracellular subtilisin protease is involved in inhibition 分子名称: ACETATE ION, SODIUM ION, Serine protease, ... 著者 Bjerga, G.E.K, Larsen, O, Arsin, H, Williamson, A.K, Garcia-Moyano, A, Leiros, I, Puntervoll, P. 登録日 2017-12-14 公開日 2018-06-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.298 Å) 主引用文献 Mutational analysis of the pro-peptide of a marine intracellular subtilisin protease supports its role in inhibition. Proteins, 86, 2018
7R3U	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: 1-[4-(1,2,3-thiadiazol-4-yl)phenyl]methanamine, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Snee, M, Katariya, M, Leys, D, Levy, C. 登録日 2022-02-07 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7RSA	STRUCTURE OF PHOSPHATE-FREE RIBONUCLEASE A REFINED AT 1.26 ANGSTROMS 分子名称: RIBONUCLEASE A, TERTIARY-BUTYL ALCOHOL 著者 Wlodawer, A, Gilliland, G.L. 登録日 1988-06-10 公開日 1988-10-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Structure of phosphate-free ribonuclease A refined at 1.26 A. Biochemistry, 27, 1988
6RAV	Complement factor B protease domain in complex with the reversible inhibitor 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic acid 分子名称: 4-[(2~{S},4~{S})-4-ethoxy-1-[(5-methoxy-7-methyl-1~{H}-indol-4-yl)methyl]piperidin-2-yl]benzoic acid, Complement factor B, SULFATE ION, ... 著者 Adams, C.M, Sellner, H, Ehara, T, Mac Sweeney, A, Crowley, M, Anderson, K, Karki, R, Mainolfi, N, Valeur, E, Sirockin, F, Gerhartz, B, Erbel, P, Hughes, N, Smith, T.M, Cumin, F, Argikar, U, Mogi, M, Sedrani, R, Wiesmann, C, Jaffee, B, Maibaum, J, Flohr, S, Harrison, R, Eder, J. 登録日 2019-04-08 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Small-molecule factor B inhibitor for the treatment of complement-mediated diseases. Proc.Natl.Acad.Sci.USA, 116, 2019
6F02	Crystal structure of human glycosylated kallistatin at 3.0 Angstrom resolution 分子名称: Kallistatin, SULFATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zhou, A, Ma, L. 登録日 2017-11-17 公開日 2018-12-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of human Kallistatin To Be Published

<245246247248249250251252253254255256257258259260>