7OW7
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6KL7
| Beta-arrestin 1 mutant S13D/T275D | 分子名称: | 1,2-ETHANEDIOL, BARIUM ION, Beta-arrestin-1 | 著者 | Kang, H, Choi, H.J. | 登録日 | 2019-07-29 | 公開日 | 2020-01-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Conformational Dynamics and Functional Implications of Phosphorylated beta-Arrestins. Structure, 28, 2020
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7WTW
| Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
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7WTT
| Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1) | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
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6KDK
| HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | 著者 | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | 登録日 | 2019-07-02 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
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7WTU
| Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (without CK1) | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
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1KXA
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7WTV
| Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A2 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
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9EQJ
| Crystal structure of pVHL:EloB:EloC in complex with MP-1-39 | 分子名称: | (2S,4R)-1-[(2R)-2-[(1-fluoranylcyclopropyl)carbonylamino]-3-methyl-3-[[cis-4-(morpholin-4-ylmethyl)cyclohexyl]methylsulfanyl]butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Kroupova, A, Pierri, M, Liu, X, Ciulli, A. | 登録日 | 2024-03-21 | 公開日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity. Bioorg.Med.Chem.Lett., 110, 2024
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9EQM
| Crystal structure of pVHL:EloB:EloC in complex with MP-1-21 | 分子名称: | (2S,4R)-1-[(2R)-2-[(1-fluoranylcyclopropyl)carbonylamino]-3-methyl-3-[[trans-4-(morpholin-4-ylmethyl)cyclohexyl]methylsulfanyl]butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Kroupova, A, Pierri, M, Liu, X, Ciulli, A. | 登録日 | 2024-03-21 | 公開日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity. Bioorg.Med.Chem.Lett., 110, 2024
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6ZDU
| Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric RNA | 分子名称: | Chains: C,D, Telomerase reverse transcriptase | 著者 | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | 登録日 | 2020-06-15 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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6ZDP
| Structure of telomerase from Candida Tropicalis in complexe with TWJ fragment of telomeric RNA | 分子名称: | Chains: B, POTASSIUM ION, Telomerase reverse transcriptase | 著者 | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | 登録日 | 2020-06-15 | 公開日 | 2021-04-28 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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8IFD
| Dibekacin-added human 80S ribosome | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8IFE
| Arbekacin-added human 80S ribosome | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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5XQM
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8R1G
| Dimeric ternary structure of E6AP-E6-p53 | 分子名称: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | 著者 | Sandate, C.R, Chakrabory, D, Kater, L, Kempf, G, Thoma, N.H. | 登録日 | 2023-11-01 | 公開日 | 2023-12-06 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | 主引用文献 | Structural insights into viral hijacking of p53 by E6 and E6AP Biorxiv, 2023
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8R1F
| Monomeric E6AP-E6-p53 ternary complex | 分子名称: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | 著者 | Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H. | 登録日 | 2023-11-01 | 公開日 | 2023-12-06 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Structural insights into viral hijacking of p53 by E6 and E6AP Biorxiv, 2023
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4DQY
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7ONB
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7CPV
| Cryo-EM structure of 80S ribosome from mouse testis | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | 著者 | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | 登録日 | 2020-08-08 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
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8YFE
| Cryo EM structure of Komagataella phaffii Rat1-Rai1 complex | 分子名称: | 5'-3' exoribonuclease, Decapping nuclease | 著者 | Yanagisawa, T, Murayama, Y, Ehara, H, Sekine, S.I. | 登録日 | 2024-02-24 | 公開日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024
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7CPU
| Cryo-EM structure of 80S ribosome from mouse kidney | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | 著者 | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | 登録日 | 2020-08-08 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
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6SWA
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8XXM
| Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | 登録日 | 2024-01-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXN
| Cryo-EM structure of the human 43S ribosome with PDCD4 | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | 登録日 | 2024-01-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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