PDB: 7990 件ウェブページステータス検索Chemie searchBIRD

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5W7V	CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril 分子名称: TAR DNA-binding protein 43 著者 Guenther, E.L, Ge, P, Eisenberg, D.S. 登録日 2017-06-20 公開日 2018-03-14 最終更新日 2025-05-21 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat. Struct. Mol. Biol., 25, 2018
5T86	Crystal structure of CDI complex from E. coli A0 34/86 分子名称: ACETATE ION, CdiA toxin, CdiI immunity protein 著者 Michalska, K, Stols, L, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) 登録日 2016-09-06 公開日 2017-09-13 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of CDI complex from E. coli A0 34/86 To Be Published
5TJ2	Gasdermin-B C-terminal domain containing the polymorphism residues Gly299:Ser306 fused to maltose binding protein 分子名称: Sugar ABC transporter substrate-binding protein,Gasdermin-B fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Chao, L.K, Herzberg, O. 登録日 2016-10-03 公開日 2017-02-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Human Gasdermin-B and disease: Sulfatide Binding, Caspase cleavage, and Structural impact of Asthma- and IBS-Associated Polymorphism Proc.Natl.Acad.Sci.Usa, 2017
6N3B	SegA-asym, conformation of TDP-43 low complexity domain segment A asym 分子名称: TAR DNA-binding protein 43 著者 Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. 登録日 2018-11-14 公開日 2019-06-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26, 2019
5T8Q	Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to aryl pyrrole fragment 17 分子名称: 1-[(2-chlorophenyl)methyl]pyrrole-2-carboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION 著者 Smith, M.A, McEwan, P.A, Hymowitz, S.G. 登録日 2016-09-08 公開日 2017-01-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Structure-Based Design of Tricyclic NF-kappa B Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K). J. Med. Chem., 60, 2017
8XH1	Orthorhombic crystal structure of green fluorescent protein nowGFP at pH 9.0 分子名称: GLYCEROL, nowGFP 著者 Kim, C.U, Kim, J.K. 登録日 2023-12-16 公開日 2024-09-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparison of two crystal polymorphs of NowGFP reveals a new conformational state trapped by crystal packing. Acta Crystallogr D Struct Biol, 80, 2024
8XH0	Monoclinic crystal structure of green fluorescent protein nowGFP at pH 4.8 分子名称: GLYCEROL, nowGFP 著者 Kim, C.U, Kim, J.K. 登録日 2023-12-16 公開日 2024-09-11 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Comparison of two crystal polymorphs of NowGFP reveals a new conformational state trapped by crystal packing. Acta Crystallogr D Struct Biol, 80, 2024
8XH2	Orthorhombic crystal structure of green fluorescent protein nowGFP at pH 6.0 分子名称: GLYCEROL, nowGFP 著者 Kim, C.U, Kim, J.K. 登録日 2023-12-16 公開日 2024-09-11 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Comparison of two crystal polymorphs of NowGFP reveals a new conformational state trapped by crystal packing. Acta Crystallogr D Struct Biol, 80, 2024
6HGF	Crystal structure of Alpha1-antichymotrypsin variant NewBG-II: a new binding globulin in complex with cortisol 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGG	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with cortisol 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.787 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6HGM	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III-allo: an allosterically controlled new binding globulin with an unprecedentedly high ligand release efficacy 分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CALCIUM ION, ... 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.369 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
5TJ3	Crystal structure of wild type alkaline phosphatase PafA to 1.7A resolution 分子名称: Alkaline phosphatase PafA, ZINC ION 著者 Lyubimov, A.Y, Sunden, F, Ressl, S, Herschlag, D. 登録日 2016-10-03 公開日 2016-11-16 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanistic and Evolutionary Insights from Comparative Enzymology of Phosphomonoesterases and Phosphodiesterases across the Alkaline Phosphatase Superfamily. J.Am.Chem.Soc., 138, 2016
6ARC	Monoclinic EutL - structure determined from merged "Group 1" data 分子名称: CHLORIDE ION, Ethanolamine utilization protein, SODIUM ION 著者 Thompson, M.C, Cascio, D, Yeates, T.O. 登録日 2017-08-22 公開日 2017-10-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism. Acta Crystallogr D Struct Biol, 74, 2018
5T8O	Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to Imidazobenzoxepin Compound 3 分子名称: 10-(3-methyl-3-oxidanyl-but-1-ynyl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2-carboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION 著者 Smith, M.A, McEwan, P, Hymowitz, S.G. 登録日 2016-09-08 公開日 2017-01-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structure-Based Design of Tricyclic NF-kappa B Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K). J. Med. Chem., 60, 2017
6ARD	Monoclinic EutL - structure determined from merged "Group 2" data 分子名称: Ethanolamine utilization protein, SODIUM ION 著者 Thompson, M.C, Cascio, D, Yeates, T.O. 登録日 2017-08-22 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism. Acta Crystallogr D Struct Biol, 74, 2018
6B73	Crystal Structure of a nanobody-stabilized active state of the kappa-opioid receptor 分子名称: CHOLESTEROL, N-[(5alpha,6beta)-17-(cyclopropylmethyl)-3-hydroxy-7,8-didehydro-4,5-epoxymorphinan-6-yl]-3-iodobenzamide, Nanobody, ... 著者 Che, T, Majumdar, S, Zaidi, S.A, Kormos, C, McCorvy, J.D, Wang, S, Mosier, P.D, Uprety, R, Vardy, E, Krumm, B.E, Han, G.W, Lee, M.Y, Pardon, E, Steyaert, J, Huang, X.P, Strachan, R.T, Tribo, A.R, Pasternak, G.W, Carroll, I.F, Stevens, R.C, Cherezov, V, Katritch, V, Wacker, D, Roth, B.L. 登録日 2017-10-03 公開日 2018-01-17 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell, 172, 2018
3D25	Crystal structure of HA-1 minor histocompatibility antigen bound to human class I MHC HLA-A2 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Nicholls, S, Piper, K.P, Mohammed, F, Dafforn, T.R, Tenzer, S, Salim, M, Mahendra, P, Craddock, C, van Endert, P, Schild, H, Cobbold, M, Engelhard, V.H, Moss, P.A.H, Willcox, B.E. 登録日 2008-05-07 公開日 2009-02-10 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition Proc.Natl.Acad.Sci.USA, 106, 2009
5UE3	proMMP-9desFnII 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Matrix metalloproteinase-9, ... 著者 Alexander, R.S, Spurlino, J, Milligan, C. 登録日 2016-12-29 公開日 2017-09-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation. J. Biol. Chem., 292, 2017
5KQY	Protease E35D-DRV 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease E35D-DRV 著者 Liu, Z, Poole, K.M, Mahon, B.P, McKenna, R, Fanucci, G.E. 登録日 2016-07-06 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution. J.Biol.Chem., 291, 2016
5KR1	Protease PR5-DRV 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease PR5-DRV 著者 Liu, Z, Poole, K.M, Mahon, B.P, McKenna, R, Fanucci, G.E. 登録日 2016-07-06 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution. J.Biol.Chem., 291, 2016
3Q2X	Structure of an amyloid forming peptide NKGAII (residues 27-32) from amyloid beta 分子名称: Amyloid beta A4 protein 著者 Soriaga, A.B, Sawaya, M.R, Eisenberg, D. 登録日 2010-12-20 公開日 2011-10-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 Molecular basis for amyloid-beta polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
5KQX	Protease E35D-SQV 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Protease E35D-SQV 著者 Liu, Z, Poole, K.M, Mahon, B.P, McKenna, R, Fanucci, G.E. 登録日 2016-07-06 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution. J.Biol.Chem., 291, 2016
3PZZ	Structure of an amyloid forming peptide GAIIGL (29-34) from amyloid beta 分子名称: Amyloid beta A4 protein 著者 Soriaga, A.B, Laganowsky, A.L, Sawaya, M.R, Eisenberg, D. 登録日 2010-12-14 公開日 2011-10-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Molecular basis for amyloid-beta polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
6VLT	Crystal Structure of Human P450 2C9*2 Genetic Variant in Complex with Losartan 分子名称: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shah, M.B. 登録日 2020-01-25 公開日 2020-09-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Structure of Cytochrome P450 2C9*2 in Complex with Losartan: Insights into the Effect of Genetic Polymorphism. Mol.Pharmacol., 98, 2020
6W3N	APE1 exonuclease substrate complex D148E 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(C7R))-3'), ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-09 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020

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