5TJ2
Gasdermin-B C-terminal domain containing the polymorphism residues Gly299:Ser306 fused to maltose binding protein
Summary for 5TJ2
| Entry DOI | 10.2210/pdb5tj2/pdb |
| Related | 5TIB 5TJ4 |
| Related PRD ID | PRD_900001 |
| Descriptor | Sugar ABC transporter substrate-binding protein,Gasdermin-B fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (3 entities in total) |
| Functional Keywords | alpha helices, fusion protein, c-terminal domain, 1 snp, lipid binding protein |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 4 |
| Total formula weight | 243215.41 |
| Authors | Chao, L.K.,Herzberg, O. (deposition date: 2016-10-03, release date: 2017-02-01, Last modification date: 2023-10-04) |
| Primary citation | Chao, L.K.,Kulakova, L.,Herzberg, O. Human Gasdermin-B and disease: Sulfatide Binding, Caspase cleavage, and Structural impact of Asthma- and IBS-Associated Polymorphism Proc.Natl.Acad.Sci.Usa, 2017 Cited by DOI: 10.1073/pnas.1616783114PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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